@article{ WOS:000371103600011,
Author = {Bavetsias, Vassilios and Lanigan, Rachel M. and Ruda, Gian Filippo and
   Atrash, Butrus and McLaughlin, Mark G. and Tumber, Anthony and Mok, N.
   Yi and Le Bihan, Yann-Vai and Dempster, Sally and Boxall, Katherine J.
   and Jeganathan, Fiona and Hatch, Stephanie B. and Savitsky, Pavel and
   Velupillai, Srikannathasan and Krojer, Tobias and England, Katherine S.
   and Sejberg, Jimmy and Thai, Ching and Donovan, Adam and Pal, Akos and
   Scozzafava, Giuseppe and Bennett, James M. and Kawamura, Akane and
   Johansson, Catrine and Szykowska, Aleksandra and Gileadi, Carina and
   Burgess-Brown, Nicola A. and von Delft, Frank and Oppermann, Udo and
   Walters, Zoe and Shipley, Janet and Raynaud, Florence I. and Westaway,
   Susan M. and Prinjha, Rab K. and Fedorov, Oleg and Burke, Rosemary and
   Schofield, Christopher J. and Westwood, Isaac M. and Bountra, Chas and
   Mueller, Susanne and van Montfort, Rob L. M. and Brennan, Paul E. and
   Blagg, Julian},
Title = {8-Substituted Pyrido{[}3,4-d]pyrimidin-4(3H)-one
   Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1)
   Histone Lysine Demethylase Inhibitors},
Journal = {JOURNAL OF MEDICINAL CHEMISTRY},
Year = {2016},
Volume = {59},
Number = {4, SI},
Pages = {1388-1409},
Month = {FEB 25},
DOI = {10.1021/acs.jmedchem.5b01635},
ISSN = {0022-2623},
EISSN = {1520-4804},
ResearcherID-Numbers = {Krojer, Tobias/ABE-3829-2021
   Lanigan, Rachel/B-4830-2015
   Fedorov, Oleg/B-6412-2014
   McLaughlin, Mark/N-8192-2019
   Knapp, Stefan/AAG-2347-2019
   Kawamura, Akane/I-4047-2018
   },
ORCID-Numbers = {Brennan, Paul/0000-0002-8950-7646
   Muller-Knapp, Susanne/0000-0003-2402-4157
   Raynaud, Florence/0000-0003-0957-6279
   Bennett, James/0000-0003-1396-8400
   Hatch, Stephanie/0000-0002-7401-9279
   England, Katherine/0000-0002-4921-7505
   Le Bihan, Yann-Vai/0000-0002-6850-9706
   McLaughlin, Mark/0000-0002-5999-4703
   Walters, Zoe/0000-0002-1835-5868
   Schofield, Christopher/0000-0002-0290-6565
   Savitsky, Pavel/0000-0001-8584-7750
   Kawamura, Akane/0000-0003-1169-5082
   Ruda, Gian Filippo/0000-0001-6150-2715
   von Delft, Frank/0000-0003-0378-0017
   Shipley, Janet/0000-0001-6748-8678
   Krojer, Tobias/0000-0003-0661-0814
   Schofield, Chris/0009-0008-4988-0199},
Unique-ID = {WOS:000371103600011},
}

{"_id":"iDoEyom6W5qFTkuKE","bibbaseid":"bavetsias-lanigan-ruda-atrash-mclaughlin-tumber-mok-lebihan-etal-8substitutedpyrido34dpyrimidin43honederivativesaspotentcellpermeablekdm4jmjd2andkdm5jarid1histonelysinedemethylaseinhibitors-2016","author_short":["Bavetsias, V.","Lanigan, R. M.","Ruda, G. F.","Atrash, B.","McLaughlin, M. G.","Tumber, A.","Mok, N. Y.","Le Bihan, Y.","Dempster, S.","Boxall, K. J.","Jeganathan, F.","Hatch, S. B.","Savitsky, P.","Velupillai, S.","Krojer, T.","England, K. S.","Sejberg, J.","Thai, C.","Donovan, A.","Pal, A.","Scozzafava, G.","Bennett, J. M.","Kawamura, A.","Johansson, C.","Szykowska, A.","Gileadi, C.","Burgess-Brown, N. A.","von Delft, F.","Oppermann, U.","Walters, Z.","Shipley, J.","Raynaud, F. I.","Westaway, S. M.","Prinjha, R. K.","Fedorov, O.","Burke, R.","Schofield, C. J.","Westwood, I. M.","Bountra, C.","Mueller, S.","van Montfort, R. L. M.","Brennan, P. E.","Blagg, J."],"bibdata":{"bibtype":"article","type":"article","author":[{"propositions":[],"lastnames":["Bavetsias"],"firstnames":["Vassilios"],"suffixes":[]},{"propositions":[],"lastnames":["Lanigan"],"firstnames":["Rachel","M."],"suffixes":[]},{"propositions":[],"lastnames":["Ruda"],"firstnames":["Gian","Filippo"],"suffixes":[]},{"propositions":[],"lastnames":["Atrash"],"firstnames":["Butrus"],"suffixes":[]},{"propositions":[],"lastnames":["McLaughlin"],"firstnames":["Mark","G."],"suffixes":[]},{"propositions":[],"lastnames":["Tumber"],"firstnames":["Anthony"],"suffixes":[]},{"propositions":[],"lastnames":["Mok"],"firstnames":["N.","Yi"],"suffixes":[]},{"propositions":[],"lastnames":["Le","Bihan"],"firstnames":["Yann-Vai"],"suffixes":[]},{"propositions":[],"lastnames":["Dempster"],"firstnames":["Sally"],"suffixes":[]},{"propositions":[],"lastnames":["Boxall"],"firstnames":["Katherine","J."],"suffixes":[]},{"propositions":[],"lastnames":["Jeganathan"],"firstnames":["Fiona"],"suffixes":[]},{"propositions":[],"lastnames":["Hatch"],"firstnames":["Stephanie","B."],"suffixes":[]},{"propositions":[],"lastnames":["Savitsky"],"firstnames":["Pavel"],"suffixes":[]},{"propositions":[],"lastnames":["Velupillai"],"firstnames":["Srikannathasan"],"suffixes":[]},{"propositions":[],"lastnames":["Krojer"],"firstnames":["Tobias"],"suffixes":[]},{"propositions":[],"lastnames":["England"],"firstnames":["Katherine","S."],"suffixes":[]},{"propositions":[],"lastnames":["Sejberg"],"firstnames":["Jimmy"],"suffixes":[]},{"propositions":[],"lastnames":["Thai"],"firstnames":["Ching"],"suffixes":[]},{"propositions":[],"lastnames":["Donovan"],"firstnames":["Adam"],"suffixes":[]},{"propositions":[],"lastnames":["Pal"],"firstnames":["Akos"],"suffixes":[]},{"propositions":[],"lastnames":["Scozzafava"],"firstnames":["Giuseppe"],"suffixes":[]},{"propositions":[],"lastnames":["Bennett"],"firstnames":["James","M."],"suffixes":[]},{"propositions":[],"lastnames":["Kawamura"],"firstnames":["Akane"],"suffixes":[]},{"propositions":[],"lastnames":["Johansson"],"firstnames":["Catrine"],"suffixes":[]},{"propositions":[],"lastnames":["Szykowska"],"firstnames":["Aleksandra"],"suffixes":[]},{"propositions":[],"lastnames":["Gileadi"],"firstnames":["Carina"],"suffixes":[]},{"propositions":[],"lastnames":["Burgess-Brown"],"firstnames":["Nicola","A."],"suffixes":[]},{"propositions":["von"],"lastnames":["Delft"],"firstnames":["Frank"],"suffixes":[]},{"propositions":[],"lastnames":["Oppermann"],"firstnames":["Udo"],"suffixes":[]},{"propositions":[],"lastnames":["Walters"],"firstnames":["Zoe"],"suffixes":[]},{"propositions":[],"lastnames":["Shipley"],"firstnames":["Janet"],"suffixes":[]},{"propositions":[],"lastnames":["Raynaud"],"firstnames":["Florence","I."],"suffixes":[]},{"propositions":[],"lastnames":["Westaway"],"firstnames":["Susan","M."],"suffixes":[]},{"propositions":[],"lastnames":["Prinjha"],"firstnames":["Rab","K."],"suffixes":[]},{"propositions":[],"lastnames":["Fedorov"],"firstnames":["Oleg"],"suffixes":[]},{"propositions":[],"lastnames":["Burke"],"firstnames":["Rosemary"],"suffixes":[]},{"propositions":[],"lastnames":["Schofield"],"firstnames":["Christopher","J."],"suffixes":[]},{"propositions":[],"lastnames":["Westwood"],"firstnames":["Isaac","M."],"suffixes":[]},{"propositions":[],"lastnames":["Bountra"],"firstnames":["Chas"],"suffixes":[]},{"propositions":[],"lastnames":["Mueller"],"firstnames":["Susanne"],"suffixes":[]},{"propositions":["van"],"lastnames":["Montfort"],"firstnames":["Rob","L.","M."],"suffixes":[]},{"propositions":[],"lastnames":["Brennan"],"firstnames":["Paul","E."],"suffixes":[]},{"propositions":[],"lastnames":["Blagg"],"firstnames":["Julian"],"suffixes":[]}],"title":"8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors","journal":"JOURNAL OF MEDICINAL CHEMISTRY","year":"2016","volume":"59","number":"4, SI","pages":"1388-1409","month":"FEB 25","doi":"10.1021/acs.jmedchem.5b01635","issn":"0022-2623","eissn":"1520-4804","researcherid-numbers":"Krojer, Tobias/ABE-3829-2021 Lanigan, Rachel/B-4830-2015 Fedorov, Oleg/B-6412-2014 McLaughlin, Mark/N-8192-2019 Knapp, Stefan/AAG-2347-2019 Kawamura, Akane/I-4047-2018 ","orcid-numbers":"Brennan, Paul/0000-0002-8950-7646 Muller-Knapp, Susanne/0000-0003-2402-4157 Raynaud, Florence/0000-0003-0957-6279 Bennett, James/0000-0003-1396-8400 Hatch, Stephanie/0000-0002-7401-9279 England, Katherine/0000-0002-4921-7505 Le Bihan, Yann-Vai/0000-0002-6850-9706 McLaughlin, Mark/0000-0002-5999-4703 Walters, Zoe/0000-0002-1835-5868 Schofield, Christopher/0000-0002-0290-6565 Savitsky, Pavel/0000-0001-8584-7750 Kawamura, Akane/0000-0003-1169-5082 Ruda, Gian Filippo/0000-0001-6150-2715 von Delft, Frank/0000-0003-0378-0017 Shipley, Janet/0000-0001-6748-8678 Krojer, Tobias/0000-0003-0661-0814 Schofield, Chris/0009-0008-4988-0199","unique-id":"WOS:000371103600011","bibtex":"@article{ WOS:000371103600011,\nAuthor = {Bavetsias, Vassilios and Lanigan, Rachel M. and Ruda, Gian Filippo and\n Atrash, Butrus and McLaughlin, Mark G. and Tumber, Anthony and Mok, N.\n Yi and Le Bihan, Yann-Vai and Dempster, Sally and Boxall, Katherine J.\n and Jeganathan, Fiona and Hatch, Stephanie B. and Savitsky, Pavel and\n Velupillai, Srikannathasan and Krojer, Tobias and England, Katherine S.\n and Sejberg, Jimmy and Thai, Ching and Donovan, Adam and Pal, Akos and\n Scozzafava, Giuseppe and Bennett, James M. and Kawamura, Akane and\n Johansson, Catrine and Szykowska, Aleksandra and Gileadi, Carina and\n Burgess-Brown, Nicola A. and von Delft, Frank and Oppermann, Udo and\n Walters, Zoe and Shipley, Janet and Raynaud, Florence I. and Westaway,\n Susan M. and Prinjha, Rab K. and Fedorov, Oleg and Burke, Rosemary and\n Schofield, Christopher J. and Westwood, Isaac M. and Bountra, Chas and\n Mueller, Susanne and van Montfort, Rob L. M. and Brennan, Paul E. and\n Blagg, Julian},\nTitle = {8-Substituted Pyrido{[}3,4-d]pyrimidin-4(3H)-one\n Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1)\n Histone Lysine Demethylase Inhibitors},\nJournal = {JOURNAL OF MEDICINAL CHEMISTRY},\nYear = {2016},\nVolume = {59},\nNumber = {4, SI},\nPages = {1388-1409},\nMonth = {FEB 25},\nDOI = {10.1021/acs.jmedchem.5b01635},\nISSN = {0022-2623},\nEISSN = {1520-4804},\nResearcherID-Numbers = {Krojer, Tobias/ABE-3829-2021\n Lanigan, Rachel/B-4830-2015\n Fedorov, Oleg/B-6412-2014\n McLaughlin, Mark/N-8192-2019\n Knapp, Stefan/AAG-2347-2019\n Kawamura, Akane/I-4047-2018\n },\nORCID-Numbers = {Brennan, Paul/0000-0002-8950-7646\n Muller-Knapp, Susanne/0000-0003-2402-4157\n Raynaud, Florence/0000-0003-0957-6279\n Bennett, James/0000-0003-1396-8400\n Hatch, Stephanie/0000-0002-7401-9279\n England, Katherine/0000-0002-4921-7505\n Le Bihan, Yann-Vai/0000-0002-6850-9706\n McLaughlin, Mark/0000-0002-5999-4703\n Walters, Zoe/0000-0002-1835-5868\n Schofield, Christopher/0000-0002-0290-6565\n Savitsky, Pavel/0000-0001-8584-7750\n Kawamura, Akane/0000-0003-1169-5082\n Ruda, Gian Filippo/0000-0001-6150-2715\n von Delft, Frank/0000-0003-0378-0017\n Shipley, Janet/0000-0001-6748-8678\n Krojer, Tobias/0000-0003-0661-0814\n Schofield, Chris/0009-0008-4988-0199},\nUnique-ID = {WOS:000371103600011},\n}\n\n","author_short":["Bavetsias, V.","Lanigan, R. M.","Ruda, G. F.","Atrash, B.","McLaughlin, M. G.","Tumber, A.","Mok, N. Y.","Le Bihan, Y.","Dempster, S.","Boxall, K. J.","Jeganathan, F.","Hatch, S. B.","Savitsky, P.","Velupillai, S.","Krojer, T.","England, K. S.","Sejberg, J.","Thai, C.","Donovan, A.","Pal, A.","Scozzafava, G.","Bennett, J. M.","Kawamura, A.","Johansson, C.","Szykowska, A.","Gileadi, C.","Burgess-Brown, N. A.","von Delft, F.","Oppermann, U.","Walters, Z.","Shipley, J.","Raynaud, F. I.","Westaway, S. M.","Prinjha, R. K.","Fedorov, O.","Burke, R.","Schofield, C. J.","Westwood, I. M.","Bountra, C.","Mueller, S.","van Montfort, R. L. M.","Brennan, P. E.","Blagg, J."],"key":"WOS:000371103600011","id":"WOS:000371103600011","bibbaseid":"bavetsias-lanigan-ruda-atrash-mclaughlin-tumber-mok-lebihan-etal-8substitutedpyrido34dpyrimidin43honederivativesaspotentcellpermeablekdm4jmjd2andkdm5jarid1histonelysinedemethylaseinhibitors-2016","role":"author","urls":{},"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://bibbase.org/network/files/HECPruWhe6gDg5ZWN","dataSources":["qhzgQBKWKwmm6xY73","NBNKNR2KcNSWDgFcf","4mccB2G6uYe3AhfDs"],"keywords":[],"search_terms":["substituted","pyrido","pyrimidin","one","derivatives","potent","cell","permeable","kdm4","jmjd2","kdm5","jarid1","histone","lysine","demethylase","inhibitors","bavetsias","lanigan","ruda","atrash","mclaughlin","tumber","mok","le bihan","dempster","boxall","jeganathan","hatch","savitsky","velupillai","krojer","england","sejberg","thai","donovan","pal","scozzafava","bennett","kawamura","johansson","szykowska","gileadi","burgess-brown","von delft","oppermann","walters","shipley","raynaud","westaway","prinjha","fedorov","burke","schofield","westwood","bountra","mueller","van montfort","brennan","blagg"],"title":"8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors","year":2016}