Fabrication of calcium phosphate microcapsules using emulsion droplets stabilized with branched copolymers as templates. Bell, R. V., Rochford, L. A., Rosales, R. T. M. D., Stevens, M., Weaver, J. V. M., & Bon, S. A. F. Journal of Materials Chemistry B, 3(3):5544–5552, 2015. Publisher: Royal Society of Chemistry
Paper doi abstract bibtex We report on a versatile and time-efficient method to fabricate calcium phosphate (CaP) microcapsules by utilizing oil-in-water emulsion droplets stabilized with synthetic branched copolymer (BCP) as templates. The BCP was designed to provide a suitable architecture and functionality to produce stable emulsion droplets, and to permit the mineralization of CaP at the surface of the oil droplet when incubated in a solution containing calcium and phosphate ions. The CaP shells of the microcapsules were established to be calcium deficient hydroxyapatite with incorporated chlorine and carbonate species. These capsule walls were made fluorescent by decoration with a fluorescein–bisphosphonate conjugate.
@article{bell_fabrication_2015,
title = {Fabrication of calcium phosphate microcapsules using emulsion droplets stabilized with branched copolymers as templates},
volume = {3},
issn = {2050-750X},
url = {http://dx.doi.org/10.1039/C5TB00893J},
doi = {10.1039/c5tb00893j},
abstract = {We report on a versatile and time-efficient method to fabricate calcium phosphate (CaP) microcapsules by utilizing oil-in-water emulsion droplets stabilized with synthetic branched copolymer (BCP) as templates. The BCP was designed to provide a suitable architecture and functionality to produce stable emulsion droplets, and to permit the mineralization of CaP at the surface of the oil droplet when incubated in a solution containing calcium and phosphate ions. The CaP shells of the microcapsules were established to be calcium deficient hydroxyapatite with incorporated chlorine and carbonate species. These capsule walls were made fluorescent by decoration with a fluorescein–bisphosphonate conjugate.},
number = {3},
journal = {Journal of Materials Chemistry B},
author = {Bell, Robert V. and Rochford, Luke A. and Rosales, Rafael T. M. De and Stevens, Molly and Weaver, Jonathan V. M. and Bon, Stefan A. F.},
year = {2015},
note = {Publisher: Royal Society of Chemistry},
pages = {5544--5552},
}
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