The α2β1 isoform of guanylyl cyclase mediates plasma membrane localized nitric oxide signalling. Bellingham, M. & Evans, T. Cellular Signalling, 19:2183-2193, 2007.
The α2β1 isoform of guanylyl cyclase mediates plasma membrane localized nitric oxide signalling [link]Paper  doi  abstract   bibtex   
S2 TL;DR: It is found that cGMP generated by NO activation of the α 2 β 1 isoform of guanylyl cyclase is an exceptionally efficient mediator of nitric oxide action on membrane targets, activating CFTR far more effectively than the cytoplasmically located α 1 β 1 guanyli cyclase isoform.
@article{3d9fa10d14c0f0085140fe27200f6c30e6429ec2,
title = {The α2β1 isoform of guanylyl cyclase mediates plasma membrane localized nitric oxide signalling},
year = {2007},
url = {https://www.semanticscholar.org/paper/3d9fa10d14c0f0085140fe27200f6c30e6429ec2},
abstract = {S2 TL;DR: It is found that cGMP generated by NO activation of the α 2 β 1 isoform of guanylyl cyclase is an exceptionally efficient mediator of nitric oxide action on membrane targets, activating CFTR far more effectively than the cytoplasmically located α 1 β 1 guanyli cyclase isoform.},
author = {M. Bellingham and T. Evans},
journal = {Cellular Signalling},
volume = {19},
pages = {2183-2193},
doi = {10.1016/J.CELLSIG.2007.06.017},
}

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