@article{ belzung_benzodiazepine_1988-1,
  title = {Benzodiazepine antagonist {RO} 15-1788 partly reverses some anxiolytic effects of ethanol in the mouse},
  volume = {95},
  issn = {0033-3158},
  abstract = {The effects of the benzodiazepine ({BZD}) receptor antagonist {RO} 15-1788 (3 mg/kg) on the anxiolytic properties of ethanol in mice confronted with a light/dark choice procedure and with the staircase test were investigated. {RO} 15-1788 reversed the effects of ethanol on some of the behavioural parameters without eliciting intrinsic effects when given alone. These data closely resemble those we previously obtained with several {BZD} receptor inverse agonists such as {RO} 15-3505, {RO} 15-4513 or beta-{CCM}. Since anxiogenic-like properties of low doses of {RO} 15-1788 have been identified by other authors, it is suggested that the antagonistic action of this drug against some of the behavioural effects of ethanol could be due to its being a partial {BZD} inverse agonist.},
  language = {eng},
  number = {4},
  journal = {Psychopharmacology},
  author = {Belzung, C. and Vogel, E. and Misslin, R.},
  year = {1988},
  pmid = {2905501},
  keywords = {Animals, Anti-Anxiety Agents, Behavior, Animal, Ethanol, Flumazenil, Male, Mice},
  pages = {516--519}
}

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