Rapid and accurate T $_{\textrm{2}}$ mapping from multi-spin-echo data using Bloch-simulation-based reconstruction: Mapping Using Bloch-Simulation-Based Reconstruction. Ben-Eliezer, N., Sodickson, D. K., & Block, K. T. Magnetic Resonance in Medicine, 73(2):809–817, February, 2015. ![Rapid and accurate T $_{\textrm{2}}$ mapping from multi-spin-echo data using Bloch-simulation-based reconstruction: Mapping Using Bloch-Simulation-Based Reconstruction [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex Purpose: Quantitative T2-relaxation-based contrast has the potential to provide valuable clinical information. Practical T2mapping, however, is impaired either by prohibitively long acquisition times or by contamination of fast multiecho protoand imaging device. Quantitative T2 mapping has demonstrated merit for various applications including neurodegenerative diseases (1,2), characterization of cancerous lesions (3–5), detection of biochemical and biophysical cols by stimulated and indirect echoes. This work presents a changes in hip and knee cartilage (6–9), diagnosis of novel postprocessing approach aiming to overcome the common penalties associated with multiecho protocols, and enabling rapid and accurate mapping of T2 relaxation values. Methods: Bloch simulations are used to estimate the actual echo-modulation curve (EMC) in a multi–spin-echo experiment. Simulations are repeated for a range of T2 values and transmit field scales, yielding a database of simulated EMCs, which is then used to identify the T2 value whose EMC most closely matches the experimentally measured data at each stroke (10), assessment of diseased and posttransplant myocardial edema (11,12), and investigation of muscle physiology (13). Nevertheless, genuine quantification of T2 relaxation values remains challenging in clinical practice, mainly due to the extremely long scan times associated with single spin-echo (SE) acquisitions. These scans extend on the order of tens of minutes, a factor which not only affects patient comfort and throughput but also voxel. makes the scans highly vulnerable to motion artifacts. Results: T2 maps of both phantom and in vivo scans were successfully reconstructed, closely matching maps produced from single spin-echo data. Results were consistent over the physiological range of T2 values and across different experimental settings. Conclusion: The proposed technique allows accurate T2 mapping in clinically feasible scan times, free of user- and scanner-dependent variations, while providing a comprehensive framework that can be extended to model other parameters (e.g., T1, B1þ, B0, diffusion) and support arbitrary acquisition schemes. Magn Reson Med 73:809–817, 2015.
@article{ben-eliezer_rapid_2015,
title = {Rapid and accurate {T} $_{\textrm{2}}$ mapping from multi-spin-echo data using {Bloch}-simulation-based reconstruction: {Mapping} {Using} {Bloch}-{Simulation}-{Based} {Reconstruction}},
volume = {73},
issn = {07403194},
shorttitle = {Rapid and accurate {T} $_{\textrm{2}}$ mapping from multi-spin-echo data using {Bloch}-simulation-based reconstruction},
url = {http://doi.wiley.com/10.1002/mrm.25156},
doi = {10.1002/mrm.25156},
abstract = {Purpose: Quantitative T2-relaxation-based contrast has the potential to provide valuable clinical information. Practical T2mapping, however, is impaired either by prohibitively long acquisition times or by contamination of fast multiecho protoand imaging device. Quantitative T2 mapping has demonstrated merit for various applications including neurodegenerative diseases (1,2), characterization of cancerous lesions (3–5), detection of biochemical and biophysical cols by stimulated and indirect echoes. This work presents a changes in hip and knee cartilage (6–9), diagnosis of novel postprocessing approach aiming to overcome the common penalties associated with multiecho protocols, and enabling rapid and accurate mapping of T2 relaxation values.
Methods: Bloch simulations are used to estimate the actual echo-modulation curve (EMC) in a multi–spin-echo experiment. Simulations are repeated for a range of T2 values and transmit field scales, yielding a database of simulated EMCs, which is then used to identify the T2 value whose EMC most closely matches the experimentally measured data at each stroke (10), assessment of diseased and posttransplant myocardial edema (11,12), and investigation of muscle physiology (13). Nevertheless, genuine quantification of T2 relaxation values remains challenging in clinical practice, mainly due to the extremely long scan times associated with single spin-echo (SE) acquisitions. These scans extend on the order of tens of minutes, a factor which not only affects patient comfort and throughput but also voxel. makes the scans highly vulnerable to motion artifacts.
Results: T2 maps of both phantom and in vivo scans were successfully reconstructed, closely matching maps produced from single spin-echo data. Results were consistent over the physiological range of T2 values and across different experimental settings.
Conclusion: The proposed technique allows accurate T2 mapping in clinically feasible scan times, free of user- and scanner-dependent variations, while providing a comprehensive framework that can be extended to model other parameters (e.g., T1, B1þ, B0, diffusion) and support arbitrary acquisition schemes. Magn Reson Med 73:809–817, 2015.},
language = {en},
number = {2},
urldate = {2021-02-12},
journal = {Magnetic Resonance in Medicine},
author = {Ben-Eliezer, Noam and Sodickson, Daniel K. and Block, Kai Tobias},
month = feb,
year = {2015},
pages = {809--817},
}
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Practical T2mapping, however, is impaired either by prohibitively long acquisition times or by contamination of fast multiecho protoand imaging device. Quantitative T2 mapping has demonstrated merit for various applications including neurodegenerative diseases (1,2), characterization of cancerous lesions (3–5), detection of biochemical and biophysical cols by stimulated and indirect echoes. This work presents a changes in hip and knee cartilage (6–9), diagnosis of novel postprocessing approach aiming to overcome the common penalties associated with multiecho protocols, and enabling rapid and accurate mapping of T2 relaxation values. Methods: Bloch simulations are used to estimate the actual echo-modulation curve (EMC) in a multi–spin-echo experiment. Simulations are repeated for a range of T2 values and transmit field scales, yielding a database of simulated EMCs, which is then used to identify the T2 value whose EMC most closely matches the experimentally measured data at each stroke (10), assessment of diseased and posttransplant myocardial edema (11,12), and investigation of muscle physiology (13). Nevertheless, genuine quantification of T2 relaxation values remains challenging in clinical practice, mainly due to the extremely long scan times associated with single spin-echo (SE) acquisitions. These scans extend on the order of tens of minutes, a factor which not only affects patient comfort and throughput but also voxel. makes the scans highly vulnerable to motion artifacts. Results: T2 maps of both phantom and in vivo scans were successfully reconstructed, closely matching maps produced from single spin-echo data. Results were consistent over the physiological range of T2 values and across different experimental settings. Conclusion: The proposed technique allows accurate T2 mapping in clinically feasible scan times, free of user- and scanner-dependent variations, while providing a comprehensive framework that can be extended to model other parameters (e.g., T1, B1þ, B0, diffusion) and support arbitrary acquisition schemes. 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