Against Quantiles: Categorization of Continuous Variables in Epidemiologic Research, and Its Discontents. Bennette, C. & Vickers, A. BMC Med Res Methodol, 12(1):21+, February, 2012. doi abstract bibtex Quantiles are a staple of epidemiologic research: in contemporary epidemiologic practice, continuous variables are typically categorized into tertiles, quartiles and quintiles as a means to illustrate the relationship between a continuous exposure and a binary outcome. In this paper we argue that this approach is highly problematic and present several potential alternatives. We also discuss the perceived drawbacks of these newer statistical methods and the possible reasons for their slow adoption by epidemiologists. The use of quantiles is often inadequate for epidemiologic research with continuous variables.
@article{ben12aga,
title = {Against Quantiles: Categorization of Continuous Variables in Epidemiologic Research, and Its Discontents},
volume = {12},
issn = {1471-2288},
abstract = {Quantiles are a staple of epidemiologic research: in contemporary epidemiologic practice, continuous variables are typically categorized into tertiles, quartiles and quintiles as a means to illustrate the relationship between a continuous exposure and a binary outcome. In this paper we argue that this approach is highly problematic and present several potential alternatives. We also discuss the perceived drawbacks of these newer statistical methods and the possible reasons for their slow adoption by epidemiologists. The use of quantiles is often inadequate for epidemiologic research with continuous variables.},
number = {1},
journal = {BMC Med Res Methodol},
doi = {10.1186/1471-2288-12-21},
author = {Bennette, Caroline and Vickers, Andrew},
month = feb,
year = {2012},
keywords = {epidemiology,teaching-mds,cutpoints,categorization,dichotomization},
pages = {21+},
citeulike-article-id = {10398554},
citeulike-attachment-1 = {ben12aga.pdf; /pdf/user/harrelfe/article/10398554/1105032/ben12aga.pdf; 30d8b922169fca1fda79552f2539c4c5b4a6a32f},
citeulike-linkout-0 = {http://dx.doi.org/10.1186/1471-2288-12-21},
citeulike-linkout-1 = {http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353173/},
citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/22375553},
citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=22375553},
day = {29},
pmcid = {PMC3353173},
pmid = {22375553},
posted-at = {2017-03-18 15:24:49},
priority = {0},
annote = {terrific graphical examples; nice display of outcome heterogeneity within quantile groups of PSA}
}
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