{"_id":"uCMiMJYvDifFihW2L","bibbaseid":"benson-fernandez-barth-demoliner-horrocks-herrington-abad-delgado-etal-scotfluorssmallconjugatableorthogonalandtunablefluorophoresforinvivoimagingofcellmetabolism-2019","author_short":["Benson, S.","Fernandez, A.","Barth, N. D","de Moliner, F.","Horrocks, M. H","Herrington, C S.","Abad, J. L.","Delgado, A.","Kelly, L.","Chang, Z.","Feng, Y.","Nishiura, M.","Hori, Y.","Kikuchi, K.","Vendrell, M."],"bibdata":{"bibtype":"article","type":"article","title":"SCOTfluors: Small, conjugatable, orthogonal, and tunable fluorophores for in vivo imaging of cell metabolism","author":[{"propositions":[],"lastnames":["Benson"],"firstnames":["Sam"],"suffixes":[]},{"propositions":[],"lastnames":["Fernandez"],"firstnames":["Antonio"],"suffixes":[]},{"propositions":[],"lastnames":["Barth"],"firstnames":["Nicole","D"],"suffixes":[]},{"propositions":["de"],"lastnames":["Moliner"],"firstnames":["Fabio"],"suffixes":[]},{"propositions":[],"lastnames":["Horrocks"],"firstnames":["Mathew","H"],"suffixes":[]},{"propositions":[],"lastnames":["Herrington"],"firstnames":["C","Simon"],"suffixes":[]},{"propositions":[],"lastnames":["Abad"],"firstnames":["Jose","Luis"],"suffixes":[]},{"propositions":[],"lastnames":["Delgado"],"firstnames":["Antonio"],"suffixes":[]},{"propositions":[],"lastnames":["Kelly"],"firstnames":["Lisa"],"suffixes":[]},{"propositions":[],"lastnames":["Chang"],"firstnames":["Ziyuan"],"suffixes":[]},{"propositions":[],"lastnames":["Feng"],"firstnames":["Yi"],"suffixes":[]},{"propositions":[],"lastnames":["Nishiura"],"firstnames":["Miyako"],"suffixes":[]},{"propositions":[],"lastnames":["Hori"],"firstnames":["Yuichiro"],"suffixes":[]},{"propositions":[],"lastnames":["Kikuchi"],"firstnames":["Kazuya"],"suffixes":[]},{"propositions":[],"lastnames":["Vendrell"],"firstnames":["Marc"],"suffixes":[]}],"abstract":"The transport and trafficking of metabolites are critical for the correct functioning of live cells. However, in situ metabolic imaging studies are hampered by the lack of fluorescent chemical structures that allow direct monitoring of small metabolites under physiological conditions with high spatial and temporal resolution. Herein, we describe SCOTfluors as novel small-sized multi-colored fluorophores for real-time tracking of essential metabolites in live cells and in vivo and for the acquisition of metabolic profiles from human cancer cells of variable origin.","journal":"Angew. Chem. Int. Ed Engl.","publisher":"Wiley","volume":"58","number":"21","pages":"6911–6915","month":"May","year":"2019","keywords":"cancer; fluorescence; imaging agents; metabolites; super-resolution imaging","copyright":"http://creativecommons.org/licenses/by/4.0/","language":"en","bibtex":"@ARTICLE{Benson2019-kd,\n title = \"{SCOTfluors}: Small, conjugatable, orthogonal, and tunable\n fluorophores for in vivo imaging of cell metabolism\",\n author = \"Benson, Sam and Fernandez, Antonio and Barth, Nicole D and de\n Moliner, Fabio and Horrocks, Mathew H and Herrington, C Simon\n and Abad, Jose Luis and Delgado, Antonio and Kelly, Lisa and\n Chang, Ziyuan and Feng, Yi and Nishiura, Miyako and Hori,\n Yuichiro and Kikuchi, Kazuya and Vendrell, Marc\",\n abstract = \"The transport and trafficking of metabolites are critical for\n the correct functioning of live cells. However, in situ\n metabolic imaging studies are hampered by the lack of\n fluorescent chemical structures that allow direct monitoring of\n small metabolites under physiological conditions with high\n spatial and temporal resolution. Herein, we describe SCOTfluors\n as novel small-sized multi-colored fluorophores for real-time\n tracking of essential metabolites in live cells and in vivo and\n for the acquisition of metabolic profiles from human cancer\n cells of variable origin.\",\n journal = \"Angew. Chem. Int. Ed Engl.\",\n publisher = \"Wiley\",\n volume = 58,\n number = 21,\n pages = \"6911--6915\",\n month = may,\n year = 2019,\n keywords = \"cancer; fluorescence; imaging agents; metabolites;\n super-resolution imaging\",\n copyright = \"http://creativecommons.org/licenses/by/4.0/\",\n language = \"en\"\n}\n\n","author_short":["Benson, S.","Fernandez, A.","Barth, N. D","de Moliner, F.","Horrocks, M. H","Herrington, C S.","Abad, J. L.","Delgado, A.","Kelly, L.","Chang, Z.","Feng, Y.","Nishiura, M.","Hori, Y.","Kikuchi, K.","Vendrell, M."],"bibbaseid":"benson-fernandez-barth-demoliner-horrocks-herrington-abad-delgado-etal-scotfluorssmallconjugatableorthogonalandtunablefluorophoresforinvivoimagingofcellmetabolism-2019","role":"author","urls":{},"keyword":["cancer; fluorescence; imaging agents; metabolites; super-resolution imaging"],"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://bibbase.org/f/SnzpCnctps9apFAde/MyRefs.bib","dataSources":["P4DL9yCkBYWMTxTMC","6RizfyANYFwZbeYCF","hos8GKTiSWJrJ8p57","jYJBHEqqdSqSw3E7J","DrBTLzMk52FTGMmNJ"],"keywords":["cancer; fluorescence; imaging agents; metabolites; super-resolution imaging"],"search_terms":["scotfluors","small","conjugatable","orthogonal","tunable","fluorophores","vivo","imaging","cell","metabolism","benson","fernandez","barth","de moliner","horrocks","herrington","abad","delgado","kelly","chang","feng","nishiura","hori","kikuchi","vendrell"],"title":"SCOTfluors: Small, conjugatable, orthogonal, and tunable fluorophores for in vivo imaging of cell metabolism","year":2019}