Accounting for Multiplicities in Assessing Drug Safety: A Three-Level Hierarchical Mixture Model. Berry, S. M. & Berry, D. A. Biometrics, 60:418-426, 2004.
bibtex   
@article{ber04acc,
  title = {Accounting for Multiplicities in Assessing Drug Safety: {{A}} Three-Level Hierarchical Mixture Model},
  volume = {60},
  journal = {Biometrics},
  author = {Berry, Scott M. and Berry, Donald A.},
  year = {2004},
  keywords = {rct,clinical-safety,pharmaceutical-safety,multiple-comparisons,drug-safety-analysis,mixture-model,pharmaceutical-trial},
  pages = {418-426},
  citeulike-article-id = {13265378},
  posted-at = {2014-07-14 14:09:55},
  priority = {0},
  annote = {borrowing information within organ system and across organ systems;AEs;adverse events;talk given studying this method at JSM2004 by jayanti\_gupta@merck.com}
}

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