P300 component in euthymic patients with bipolar disorder type I, bipolar disorder type II and healthy controls: a preliminary event-related potential study. Bersani, F. S, Minichino, A., Fattapposta, F., Mannarelli, D., Pauletti, C., Imperatori, C., Spagnoli, F., Biondi, M., & Delle Chiaie, R. Neuroreport, 26(4):206–10, March, 2015. Publisher: LIPPINCOTT WILLIAMS & WILKINS, TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
P300 component in euthymic patients with bipolar disorder type I, bipolar disorder type II and healthy controls: a preliminary event-related potential study. [link]Paper  doi  abstract   bibtex   
The aim of the present study was to investigate P300 event-related potential components in euthymic bipolar disorder type I (BDI) and bipolar disorder type II (BDII) patients and matched controls. A total of 10 BDI patients, 10 BDII patients and 10 healthy individuals were enrolled in the study. Event-related potential data were collected according to a standard auditory 'oddball' paradigm. A significant groups effect in both the peak amplitude (P\textless0.001) and the mean amplitude (P\textless0.001) was observed; post-hoc comparisons showed that the peak and mean amplitudes of BDI and BDII patients were significantly lower than the peak and mean amplitudes of the healthy controls. The neurophysiological patterns found in the present study might at least partially reflect the presence of a mild selective cognitive impairment in euthymic BDI and BDII patients. From a clinical point of view, these evidences support the potential role of cognitive interventions in the treatment of BD.
@article{bersani_p300_2015,
	title = {P300 component in euthymic patients with bipolar disorder type {I}, bipolar disorder type {II} and healthy controls: a preliminary event-related potential study.},
	volume = {26},
	issn = {1473-558X},
	url = {http://apps.webofknowledge.com/full_record.do?product=UA&search_mode=GeneralSearch&qid=2&SID=Y1MtHGxyyZH2uOu7By7&page=1&doc=27&cacheurlFromRightClick=no},
	doi = {10.1097/WNR.0000000000000329},
	abstract = {The aim of the present study was to investigate P300 event-related potential components in euthymic bipolar disorder type I (BDI) and bipolar disorder type II (BDII) patients and matched controls. A total of 10 BDI patients, 10 BDII patients and 10 healthy individuals were enrolled in the study. Event-related potential data were collected according to a standard auditory 'oddball' paradigm. A significant groups effect in both the peak amplitude (P{\textless}0.001) and the mean amplitude (P{\textless}0.001) was observed; post-hoc comparisons showed that the peak and mean amplitudes of BDI and BDII patients were significantly lower than the peak and mean amplitudes of the healthy controls. The neurophysiological patterns found in the present study might at least partially reflect the presence of a mild selective cognitive impairment in euthymic BDI and BDII patients. From a clinical point of view, these evidences support the potential role of cognitive interventions in the treatment of BD.},
	number = {4},
	urldate = {2015-05-24},
	journal = {Neuroreport},
	author = {Bersani, Francesco S and Minichino, Amedeo and Fattapposta, Francesco and Mannarelli, Daniela and Pauletti, Caterina and Imperatori, Claudio and Spagnoli, Francesco and Biondi, Massimo and Delle Chiaie, Roberto},
	month = mar,
	year = {2015},
	pmid = {25674905},
	note = {Publisher: LIPPINCOTT WILLIAMS \& WILKINS, TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA},
	keywords = {COGNITIVE IMPAIRMENT, DEFICIT, MANIPULATION, P300, P3A, PARIETAL CORTEX, RATING-SCALE, SCHIZOPHRENIA, STIMULI, TARGET, WORKING-MEMORY, bipolar disorder, event-related potential},
	pages = {206--10},
}

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