Co-prescriptions of psychotropic drugs to older patients in a general hospital

Co-prescriptions of psychotropic drugs to older patients in a general hospital. Beuscart, J., Ficheur, G., Miqueu, M., Luyckx, M., Perichon, R., Puisieux, F., Beuscart, R., Chazard, E., & Ferret, L. European Geriatric Medicine, 8(1):84–89, 2017.
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Introduction The prescription of psychotropic drugs to older patients in a hospital setting has not been extensively characterized. The objective was to describe the inappropriate co-prescriptions of psychotropic drugs in hospitalized patients aged 75 and over. Methods By analysing the medical database from 222-bed general hospital in France, we reviewed a total of 11,929 stays of at least 3 days by patients aged 75 and over. Prescriptions and co-prescriptions of psychotropic drugs were identified automatically. Anticholinergic drugs with sedative effects were considered as psychotropic drugs. An expert review was performed for stays with the co-prescription of three or more psychotropic drugs to identify inappropriate co-prescriptions. Results Administration of a psychotropic drug was identified in 5475 stays (45.9% of the total number of stays), of which 1526 (12.8% of the total) featured at least one co-prescription. Co-prescriptions of three or more psychotropic drugs for at least 3 days were identified in 374 stays (3.1% of the total). Most of these co-prescriptions (n = 334; 89.2%) were considered inappropriate because of the combination of at least two drugs from the same psychotropic class (n = 269), the absence of a clear indication for a psychotropic drug (n = 173) and a history of falls (n = 86). However, the co-prescriptions were maintained after hospital discharge in 77.4% of cases. Conclusion The co-prescriptions of psychotropic drugs should be re-evaluated in older hospitalized patients. © 2016 Elsevier Masson SAS and European Union Geriatric Medicine Society

@article{beuscart_co-prescriptions_2017,
	title = {Co-prescriptions of psychotropic drugs to older patients in a general hospital},
	volume = {8},
	doi = {10.1016/j.eurger.2016.11.012},
	abstract = {Introduction The prescription of psychotropic drugs to older patients in a hospital setting has not been extensively characterized. The objective was to describe the inappropriate co-prescriptions of psychotropic drugs in hospitalized patients aged 75 and over. Methods By analysing the medical database from 222-bed general hospital in France, we reviewed a total of 11,929 stays of at least 3 days by patients aged 75 and over. Prescriptions and co-prescriptions of psychotropic drugs were identified automatically. Anticholinergic drugs with sedative effects were considered as psychotropic drugs. An expert review was performed for stays with the co-prescription of three or more psychotropic drugs to identify inappropriate co-prescriptions. Results Administration of a psychotropic drug was identified in 5475 stays (45.9\% of the total number of stays), of which 1526 (12.8\% of the total) featured at least one co-prescription. Co-prescriptions of three or more psychotropic drugs for at least 3 days were identified in 374 stays (3.1\% of the total). Most of these co-prescriptions (n = 334; 89.2\%) were considered inappropriate because of the combination of at least two drugs from the same psychotropic class (n = 269), the absence of a clear indication for a psychotropic drug (n = 173) and a history of falls (n = 86). However, the co-prescriptions were maintained after hospital discharge in 77.4\% of cases. Conclusion The co-prescriptions of psychotropic drugs should be re-evaluated in older hospitalized patients. © 2016 Elsevier Masson SAS and European Union Geriatric Medicine Society},
	number = {1},
	journal = {European Geriatric Medicine},
	author = {Beuscart, J.-B. and Ficheur, G. and Miqueu, M. and Luyckx, M. and Perichon, R. and Puisieux, F. and Beuscart, R. and Chazard, E. and Ferret, L.},
	year = {2017},
	keywords = {Data reuse, Inappropriate prescribing, Psychotropic drugs},
	pages = {84--89},
}

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The objective was to describe the inappropriate co-prescriptions of psychotropic drugs in hospitalized patients aged 75 and over. Methods By analysing the medical database from 222-bed general hospital in France, we reviewed a total of 11,929 stays of at least 3 days by patients aged 75 and over. Prescriptions and co-prescriptions of psychotropic drugs were identified automatically. Anticholinergic drugs with sedative effects were considered as psychotropic drugs. An expert review was performed for stays with the co-prescription of three or more psychotropic drugs to identify inappropriate co-prescriptions. Results Administration of a psychotropic drug was identified in 5475 stays (45.9\\% of the total number of stays), of which 1526 (12.8\\% of the total) featured at least one co-prescription. Co-prescriptions of three or more psychotropic drugs for at least 3 days were identified in 374 stays (3.1\\% of the total). 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