Thiol-Bromo Click Reaction for One-Pot Synthesis of Star-Shaped Polymers. Beyer, V. P., Cattoz, B., & Becer, C. R. MACROMOLECULAR RAPID COMMUNICATIONS, January, 2021. Infineum UK Ltd
doi  abstract   bibtex   
Star-shaped polymers have unique physical properties and they are sought after materials in industry. However, the ease of synthesis is essential for translation of these materials into large-scale applications. Herein, a highly efficient synthetic method to prepare star-shaped polymers by combination of Cu-mediated reversible deactivation radical polymerization (Cu-RDRP) and thiol-bromo click reaction is described. Well-defined linear and block polymers with a very high bromine chain end fidelity are obtained via Cu-RDRP and subsequently react with multi-functional thiol compounds. High coupling efficiencies of larger than 90% are obtained owing to the quick and efficient reaction between thiols and alkyl bromides. Moreover, the arms of the obtained star-shaped polymers are linked via thioether bonds to the core, making them susceptible for oxidative degradation.
@article{beyer_thiol-bromo_2021,
	title = {Thiol-{Bromo} {Click} {Reaction} for {One}-{Pot} {Synthesis} of {Star}-{Shaped} {Polymers}},
	volume = {42},
	issn = {1022-1336},
	doi = {10.1002/marc.202000519},
	abstract = {Star-shaped polymers have unique physical properties and they are sought after materials in industry. However, the ease of synthesis is essential for translation of these materials into large-scale applications. Herein, a highly efficient synthetic method to prepare star-shaped polymers by combination of Cu-mediated reversible deactivation radical polymerization (Cu-RDRP) and thiol-bromo click reaction is described. Well-defined linear and block polymers with a very high bromine chain end fidelity are obtained via Cu-RDRP and subsequently react with multi-functional thiol compounds. High coupling efficiencies of larger than 90\% are obtained owing to the quick and efficient reaction between thiols and alkyl bromides. Moreover, the arms of the obtained star-shaped polymers are linked via thioether bonds to the core, making them susceptible for oxidative degradation.},
	number = {2},
	urldate = {2020-12-01},
	journal = {MACROMOLECULAR RAPID COMMUNICATIONS},
	author = {Beyer, Valentin Peter and Cattoz, Beatrice and Becer, Caglar Remzi},
	month = jan,
	year = {2021},
	note = {Infineum UK Ltd},
}

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