Preliminary report of biological basis of sensitivity to the effects of cannabis on psychosis: AKT1 and DAT1 genotype modulates the effects of δ-9-tetrahydrocannabinol on midbrain and striatal function. Bhattacharyya, S., Atakan, Z., Martin-Santos, R., Crippa, J. A., Kambeitz, J., Prata, D., Williams, S., Brammer, M., Collier, D. A., & McGuire, P. K. Molecular Psychiatry, 17(12):1152–1155, 2012. doi abstract bibtex Cannabis use can induce acute psychotic symptoms1 and increase the long-term risk of schizophrenia,2 but there is a marked interindividual variability in the susceptibility to these effects. The latter is thought to have a genetic basis, but it is unclear which particular genes are responsible.
@article{bhattacharyya_preliminary_2012,
title = {Preliminary report of biological basis of sensitivity to the effects of cannabis on psychosis: {AKT1} and {DAT1} genotype modulates the effects of δ-9-tetrahydrocannabinol on midbrain and striatal function},
volume = {17},
issn = {1359-4184},
doi = {10.1038/mp.2011.187},
abstract = {Cannabis use can induce acute psychotic symptoms1 and increase the long-term risk of schizophrenia,2 but there is a marked interindividual variability in the susceptibility to these effects. The latter is thought to have a genetic basis, but it is unclear which particular genes are responsible.},
number = {12},
journal = {Molecular Psychiatry},
author = {Bhattacharyya, S. and Atakan, Z. and Martin-Santos, R. and Crippa, J. A. and Kambeitz, J. and Prata, D. and Williams, S. and Brammer, M. and Collier, D. A. and McGuire, P. K.},
year = {2012},
pages = {1152--1155},
}
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