Surgical treatment of vaginal vault prolapse using different prosthetic mesh implants: a finite element analysis. Bhattarai, A., Jabbari, M., Anding, R., & Staat, M. tm - Technisches Messen, 85(5):331–342, April, 2018. ZSCC: 0000004
Surgical treatment of vaginal vault prolapse using different prosthetic mesh implants: a finite element analysis [link]Paper  doi  abstract   bibtex   
Particularly multiparous elderly women may suffer from vaginal vault prolapse after hysterectomy due to weak support from lax apical ligaments. A decreased amount of estrogen and progesterone in older age is assumed to remodel the collagen thereby reducing tissue stiffness. Sacrocolpopexy is either performed as open or laparoscopic surgery using prosthetic mesh implants to substitute lax ligaments. Y-shaped mesh models (DynaMesh, Gynemesh, and Ultrapro) are implanted in a 3D female pelvic floor finite element model in the extraperitoneal space from the vaginal cuff to the first sacral (S1) bone below promontory. Numerical simulations are conducted during Valsalva maneuver with weakened tissues modeled by reduced tissue stiffness. Tissues are modeled as incompressible, isotropic hyperelastic materials whereas the meshes are modeled either as orthotropic linear elastic or as isotropic hyperlastic materials. The positions of the vaginal cuff and the bladder base are calculated from the pubococcygeal line for female pelvic floor at rest, for prolapse and after repair using the three meshes. Due to mesh mechanics and mesh pore deformation along the loaded direction, the DynaMesh with regular rectangular mesh pores is found to provide better mechanical support to the organs than the Gynemesh and the Ultrapro with irregular hexagonal mesh pores.
@article{bhattarai_surgical_2018,
	title = {Surgical treatment of vaginal vault prolapse using different prosthetic mesh implants: a finite element analysis},
	volume = {85},
	copyright = {All rights reserved},
	issn = {2196-7113},
	url = {http://www.degruyter.com/view/j/teme.ahead-of-print/teme-2017-0115/teme-2017-0115.xml http://www.degruyter.com/view/j/teme.2018.85.issue-5/teme-2017-0115/teme-2017-0115.xml},
	doi = {10.1515/teme-2017-0115},
	abstract = {Particularly multiparous elderly women may suffer from vaginal vault prolapse after hysterectomy due to weak support from lax apical ligaments. A decreased amount of estrogen and progesterone in older age is assumed to remodel the collagen thereby reducing tissue stiffness. Sacrocolpopexy is either performed as open or laparoscopic surgery using prosthetic mesh implants to substitute lax ligaments. Y-shaped mesh models (DynaMesh, Gynemesh, and Ultrapro) are implanted in a 3D female pelvic floor finite element model in the extraperitoneal space from the vaginal cuff to the first sacral (S1) bone below promontory. Numerical simulations are conducted during Valsalva maneuver with weakened tissues modeled by reduced tissue stiffness. Tissues are modeled as incompressible, isotropic hyperelastic materials whereas the meshes are modeled either as orthotropic linear elastic or as isotropic hyperlastic materials. The positions of the vaginal cuff and the bladder base are calculated from the pubococcygeal line for female pelvic floor at rest, for prolapse and after repair using the three meshes. Due to mesh mechanics and mesh pore deformation along the loaded direction, the DynaMesh with regular rectangular mesh pores is found to provide better mechanical support to the organs than the Gynemesh and the Ultrapro with irregular hexagonal mesh pores.},
	number = {5},
	journal = {tm - Technisches Messen},
	author = {Bhattarai, Aroj and Jabbari, Medisa and Anding, Ralf and Staat, Manfred},
	month = apr,
	year = {2018},
	note = {ZSCC: 0000004},
	keywords = {Apical prolapse, biomechanical modeling, finite element simulation, prosthetic mesh implants, sacrocolpopexy, vaginal cuff},
	pages = {331--342},
}

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