Simultaneous determination of 16 brominated flame retardants in food and feed of animal origin by fast gas chromatography coupled to tandem mass spectrometry using atmospheric pressure chemical ionisation. Bichon, E., Guiffard, I., Vénisseau, A., Lesquin, E., Vaccher, V., Brosseaud, A., Marchand, P., & Le Bizec, B. 1459:120–128.
Simultaneous determination of 16 brominated flame retardants in food and feed of animal origin by fast gas chromatography coupled to tandem mass spectrometry using atmospheric pressure chemical ionisation [link]Paper  doi  abstract   bibtex   
A gas chromatography tandem mass spectrometry method using atmospheric pressure chemical ionisation was developed for the monitoring of 16 brominated flame retardants (7 usually monitored polybromodiphenylethers (PBDEs) and BDE #209 and 8 additional emerging and novel BFRs) in food and feed of animal origin. The developed analytical method has decreased the run time by three compared to conventional strategies, using a 2.5 m column length (5% phenyl stationary phase, 0.1 mm i.d., 0.1 ␮m f.t.), a pulsed split injection (1:5) with carrier gas helium flow rate at 0.48 mL min−1 in one run of 20 min. For most BFRs, analytical data were compared with the current analytical strategy relying on GC/EI/HRMS (double sector, R = 10000 at 10% valley). Performances in terms of sensitivity were found to meet the Commission recommendation (118/2014/EC) for nBFRs. GC/APCI/MS/MS represents a promising alternative for multi-BFRs analysis in complex matrices, in that it allows the monitoring of a wider list of contaminants in a single injection and a shorter run time.
@article{bichon_simultaneous_2016,
	title = {Simultaneous determination of 16 brominated flame retardants in food and feed of animal origin by fast gas chromatography coupled to tandem mass spectrometry using atmospheric pressure chemical ionisation},
	volume = {1459},
	issn = {00219673},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0021967316308937},
	doi = {10.1016/j.chroma.2016.07.003},
	abstract = {A gas chromatography tandem mass spectrometry method using atmospheric pressure chemical ionisation was developed for the monitoring of 16 brominated flame retardants (7 usually monitored polybromodiphenylethers ({PBDEs}) and {BDE} \#209 and 8 additional emerging and novel {BFRs}) in food and feed of animal origin. The developed analytical method has decreased the run time by three compared to conventional strategies, using a 2.5 m column length (5\% phenyl stationary phase, 0.1 mm i.d., 0.1 ␮m f.t.), a pulsed split injection (1:5) with carrier gas helium flow rate at 0.48 {mL} min−1 in one run of 20 min. For most {BFRs}, analytical data were compared with the current analytical strategy relying on {GC}/{EI}/{HRMS} (double sector, R = 10000 at 10\% valley). Performances in terms of sensitivity were found to meet the Commission recommendation (118/2014/{EC}) for {nBFRs}. {GC}/{APCI}/{MS}/{MS} represents a promising alternative for multi-{BFRs} analysis in complex matrices, in that it allows the monitoring of a wider list of contaminants in a single injection and a shorter run time.},
	pages = {120--128},
	journaltitle = {Journal of Chromatography A},
	author = {Bichon, E. and Guiffard, I. and Vénisseau, A. and Lesquin, E. and Vaccher, V. and Brosseaud, A. and Marchand, P. and Le Bizec, B.},
	urldate = {2019-03-29},
	date = {2016-08},
	langid = {english},
	file = {Bichon et al. - 2016 - Simultaneous determination of 16 brominated flame .pdf:C\:\\Users\\ygu\\Documents\\PCPOR066_YGU\\YGU\\Zotero\\storage\\KVGD2VH8\\Bichon et al. - 2016 - Simultaneous determination of 16 brominated flame .pdf:application/pdf}
}

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