{"_id":"5oH8cdMjKuniMHm6s","bibbaseid":"bigford-mendez-betancourt-burnsdrecq-backus-nash-alifestyleinterventionprogramforsuccessfullyaddressingmajorcardiometabolicrisksinpersonswithsciathreesubjectcaseseries-2017","author_short":["Bigford, G. E.","Mendez, A. J.","Betancourt, L.","Burns-Drecq, P.","Backus, D.","Nash, M. S."],"bibdata":{"bibtype":"article","type":"article","title":"A lifestyle intervention program for successfully addressing major cardiometabolic risks in persons with SCI: a three-subject case series","volume":"3","issn":"2058-6124","shorttitle":"A lifestyle intervention program for successfully addressing major cardiometabolic risks in persons with SCI","doi":"10.1038/scsandc.2017.7","abstract":"INTRODUCTION: This study is a prospective case series analyzing the effects of a comprehensive lifestyle intervention program in three patients with chronic paraplegia having major risks for the cardiometabolic syndrome (CMS). CASE PRESENTATION: Individuals underwent an intense 6-month program of circuit resistance exercise, nutrition using a Mediterranean diet and behavioral support, followed by a 6-month extension (maintenance) phase involving minimal support. The primary goal was a 7% reduction of body mass. Other outcomes analyzed insulin resistance using the HOMA-IR model, and plasma levels of fasting triglycerides and high-density lipoprotein cholesterol. All participants achieved the goal for 7% reduction of body mass and maintained the loss after the MP. Improvements were observed in 2/3 subjects for HOMA-IR and high-density lipoprotein cholesterol. All participants improved their risk for plasma triglycerides. DISCUSSION: We conclude, in a three-person case series of persons with chronic paraplegia, a lifestyle intervention program involving circuit resistance training, a calorie-restrictive Mediterranean-style diet and behavioral support, results in clinically significant loss of body mass and effectively reduced component risks for CMS and diabetes. These results were for the most part maintained after a 6-month MP involving minimal supervision.","language":"eng","journal":"Spinal Cord Series and Cases","author":[{"propositions":[],"lastnames":["Bigford"],"firstnames":["Gregory","E."],"suffixes":[]},{"propositions":[],"lastnames":["Mendez"],"firstnames":["Armando","J."],"suffixes":[]},{"propositions":[],"lastnames":["Betancourt"],"firstnames":["Luisa"],"suffixes":[]},{"propositions":[],"lastnames":["Burns-Drecq"],"firstnames":["Patricia"],"suffixes":[]},{"propositions":[],"lastnames":["Backus"],"firstnames":["Deborah"],"suffixes":[]},{"propositions":[],"lastnames":["Nash"],"firstnames":["Mark","S."],"suffixes":[]}],"year":"2017","pmid":"28382218","pmcid":"PMC5352674","keywords":"Cardiovascular diseases, Risk factors","pages":"17007","bibtex":"@article{bigford_lifestyle_2017,\n\ttitle = {A lifestyle intervention program for successfully addressing major cardiometabolic risks in persons with {SCI}: a three-subject case series},\n\tvolume = {3},\n\tissn = {2058-6124},\n\tshorttitle = {A lifestyle intervention program for successfully addressing major cardiometabolic risks in persons with {SCI}},\n\tdoi = {10.1038/scsandc.2017.7},\n\tabstract = {INTRODUCTION: This study is a prospective case series analyzing the effects of a comprehensive lifestyle intervention program in three patients with chronic paraplegia having major risks for the cardiometabolic syndrome (CMS).\nCASE PRESENTATION: Individuals underwent an intense 6-month program of circuit resistance exercise, nutrition using a Mediterranean diet and behavioral support, followed by a 6-month extension (maintenance) phase involving minimal support. The primary goal was a 7\\% reduction of body mass. Other outcomes analyzed insulin resistance using the HOMA-IR model, and plasma levels of fasting triglycerides and high-density lipoprotein cholesterol. All participants achieved the goal for 7\\% reduction of body mass and maintained the loss after the MP. Improvements were observed in 2/3 subjects for HOMA-IR and high-density lipoprotein cholesterol. All participants improved their risk for plasma triglycerides.\nDISCUSSION: We conclude, in a three-person case series of persons with chronic paraplegia, a lifestyle intervention program involving circuit resistance training, a calorie-restrictive Mediterranean-style diet and behavioral support, results in clinically significant loss of body mass and effectively reduced component risks for CMS and diabetes. These results were for the most part maintained after a 6-month MP involving minimal supervision.},\n\tlanguage = {eng},\n\tjournal = {Spinal Cord Series and Cases},\n\tauthor = {Bigford, Gregory E. and Mendez, Armando J. and Betancourt, Luisa and Burns-Drecq, Patricia and Backus, Deborah and Nash, Mark S.},\n\tyear = {2017},\n\tpmid = {28382218},\n\tpmcid = {PMC5352674},\n\tkeywords = {Cardiovascular diseases, Risk factors},\n\tpages = {17007},\n}\n\n","author_short":["Bigford, G. E.","Mendez, A. J.","Betancourt, L.","Burns-Drecq, P.","Backus, D.","Nash, M. S."],"key":"bigford_lifestyle_2017","id":"bigford_lifestyle_2017","bibbaseid":"bigford-mendez-betancourt-burnsdrecq-backus-nash-alifestyleinterventionprogramforsuccessfullyaddressingmajorcardiometabolicrisksinpersonswithsciathreesubjectcaseseries-2017","role":"author","urls":{},"keyword":["Cardiovascular diseases","Risk factors"],"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://api.zotero.org/groups/2581662/items?key=YZfATkV3PLb7DKeYtcvlNWuS&format=bibtex&limit=100","dataSources":["ji5hLFbgg8JwgJNtB"],"keywords":["cardiovascular diseases","risk factors"],"search_terms":["lifestyle","intervention","program","successfully","addressing","major","cardiometabolic","risks","persons","sci","three","subject","case","series","bigford","mendez","betancourt","burns-drecq","backus","nash"],"title":"A lifestyle intervention program for successfully addressing major cardiometabolic risks in persons with SCI: a three-subject case series","year":2017}