Depression with and without a history of psychotic symptoms in the general population: sociodemographic and clinical characteristics. Bénard, V., Pignon, B., Geoffroy, P. A., Benradia, I., Roelandt, J. L., Rolland, B., Fovet, T., D'Hondt, F., Thomas, P., Vaiva, G., & Amad, A. Journal of Affective Disorders, 273(March):247–251, Elsevier B.V., aug, 2020. ![Depression with and without a history of psychotic symptoms in the general population: sociodemographic and clinical characteristics [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex Background:: The aim of this study was to find the sociodemographic and clinical characteristics of major depressive episode (MDE) with (MDE-HPS+) and without a history of psychotic symptoms (MDE-HPS) in the general population. Methods:: The Mental Health in the General Population survey interviewed 38,694 individuals in France by using the MINI. The prevalence and sociodemographic and clinical correlates of MDE-HPS+ were assessed. Results:: Of the sample, 11.2% were diagnosed with current MDE and among them, 39.3% presented a history of at least one psychotic symptom (hallucination or delusion). Patients with MDE-HPS+ were younger with more severe social impairment than those with MDE-HPS-. We also found a higher proportion of three generations of migrants in the MDE-HPS+ group. Comorbid psychiatric disorders such as a history of a manic episode, alcohol use disorder, social anxiety, generalized anxiety disorder, and a personal history of a suicide attempt were more frequent in patients with MDE-HPS+ than in those with MDE-HPS-. Finally, we found a specific gradient of severity for psychiatric comorbid disorders depending on the number of psychotic symptoms lifetime in MDE. Limitations:: The study also has an observational cross-sectional design that does not permit causal inferences, and it is difficult to eliminate recall bias and reporting errors. Conclusion:: In the general population, patients with MDE-HPS+, when compared to MDE-HPS-, presented with a more severe clinical profile, with increased rates of psychiatric comorbidities, particularly a history of bipolar disorder and a history of a suicide attempt.
@article{BENARD2020,
abstract = {Background:: The aim of this study was to find the sociodemographic and clinical characteristics of major depressive episode (MDE) with (MDE-HPS+) and without a history of psychotic symptoms (MDE-HPS) in the general population. Methods:: The Mental Health in the General Population survey interviewed 38,694 individuals in France by using the MINI. The prevalence and sociodemographic and clinical correlates of MDE-HPS+ were assessed. Results:: Of the sample, 11.2% were diagnosed with current MDE and among them, 39.3% presented a history of at least one psychotic symptom (hallucination or delusion). Patients with MDE-HPS+ were younger with more severe social impairment than those with MDE-HPS-. We also found a higher proportion of three generations of migrants in the MDE-HPS+ group. Comorbid psychiatric disorders such as a history of a manic episode, alcohol use disorder, social anxiety, generalized anxiety disorder, and a personal history of a suicide attempt were more frequent in patients with MDE-HPS+ than in those with MDE-HPS-. Finally, we found a specific gradient of severity for psychiatric comorbid disorders depending on the number of psychotic symptoms lifetime in MDE. Limitations:: The study also has an observational cross-sectional design that does not permit causal inferences, and it is difficult to eliminate recall bias and reporting errors. Conclusion:: In the general population, patients with MDE-HPS+, when compared to MDE-HPS-, presented with a more severe clinical profile, with increased rates of psychiatric comorbidities, particularly a history of bipolar disorder and a history of a suicide attempt.},
author = {B{\'{e}}nard, Victoire and Pignon, Baptiste and Geoffroy, Pierre A. and Benradia, Imane and Roelandt, Jean Luc and Rolland, Benjamin and Fovet, Thomas and D'Hondt, Fabien and Thomas, Pierre and Vaiva, Guillaume and Amad, Ali},
doi = {10.1016/j.jad.2020.04.048},
file = {:C\:/Users/fabie/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/BENARD et al. - 2020 - Depression with and without a history of psychotic symptoms in the general population sociodemographic and clinic.pdf:pdf},
issn = {15732517},
journal = {Journal of Affective Disorders},
keywords = {Bipolar disorder,Continuum,Major depressive episode,Psychotic symptoms,Suicide},
language = {eng},
month = {aug},
number = {March},
pages = {247--251},
pmid = {32423890},
publisher = {Elsevier B.V.},
title = {{Depression with and without a history of psychotic symptoms in the general population: sociodemographic and clinical characteristics}},
url = {https://doi.org/10.1016/j.jad.2020.04.048},
volume = {273},
year = {2020}
}
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Results:: Of the sample, 11.2% were diagnosed with current MDE and among them, 39.3% presented a history of at least one psychotic symptom (hallucination or delusion). Patients with MDE-HPS+ were younger with more severe social impairment than those with MDE-HPS-. We also found a higher proportion of three generations of migrants in the MDE-HPS+ group. Comorbid psychiatric disorders such as a history of a manic episode, alcohol use disorder, social anxiety, generalized anxiety disorder, and a personal history of a suicide attempt were more frequent in patients with MDE-HPS+ than in those with MDE-HPS-. Finally, we found a specific gradient of severity for psychiatric comorbid disorders depending on the number of psychotic symptoms lifetime in MDE. Limitations:: The study also has an observational cross-sectional design that does not permit causal inferences, and it is difficult to eliminate recall bias and reporting errors. 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Methods:: The Mental Health in the General Population survey interviewed 38,694 individuals in France by using the MINI. The prevalence and sociodemographic and clinical correlates of MDE-HPS+ were assessed. Results:: Of the sample, 11.2% were diagnosed with current MDE and among them, 39.3% presented a history of at least one psychotic symptom (hallucination or delusion). Patients with MDE-HPS+ were younger with more severe social impairment than those with MDE-HPS-. We also found a higher proportion of three generations of migrants in the MDE-HPS+ group. Comorbid psychiatric disorders such as a history of a manic episode, alcohol use disorder, social anxiety, generalized anxiety disorder, and a personal history of a suicide attempt were more frequent in patients with MDE-HPS+ than in those with MDE-HPS-. Finally, we found a specific gradient of severity for psychiatric comorbid disorders depending on the number of psychotic symptoms lifetime in MDE. 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