Aesculus Hippocastanum. Bombardelli, E.; Morazzoni, P.; and Griffini, A. 67(6):483–511.
Aesculus Hippocastanum [link]Paper  abstract   bibtex   
Seeds and bark A. hippocastanum, or horse chestnut tree, have been widely used in European traditional medicine since the 16th century. Nowadays horse chestnut extracts (HCE), escin, a pure saponin and esculin, a glucosidate coumarin, are still widely employed in clinical practice mainly for the treatment of peripheral chronic venous insufficiency (CVI). Due to the effect on capillary permeability, HCE and escin have found an application in the cosmetic field. Furthermore, esculin is reported to possess microvasculokinetic activity and is indicated for the treatment of unattractiveness such as cellulitis and hair loss. More recently proanthocyanidin A2, a catechic dimer isolated from the bark, has shown an interesting protective effect against UV damage, mainly due to its very strong antioxidant properties.
@article{bombardelliAesculusHippocastanum1996,
  title = {Aesculus Hippocastanum},
  author = {Bombardelli, E. and Morazzoni, P. and Griffini, A.},
  date = {1996},
  journaltitle = {Fitoterapia},
  volume = {67},
  pages = {483--511},
  issn = {0367-326X},
  url = {http://mfkp.org/INRMM/article/13682861____to-archive},
  abstract = {Seeds and bark A. hippocastanum, or horse chestnut tree, have been widely used in European traditional medicine since the 16th century. Nowadays horse chestnut extracts (HCE), escin, a pure saponin and esculin, a glucosidate coumarin, are still widely employed in clinical practice mainly for the treatment of peripheral chronic venous insufficiency (CVI). Due to the effect on capillary permeability, HCE and escin have found an application in the cosmetic field. Furthermore, esculin is reported to possess microvasculokinetic activity and is indicated for the treatment of unattractiveness such as cellulitis and hair loss. More recently proanthocyanidin A2, a catechic dimer isolated from the bark, has shown an interesting protective effect against UV damage, mainly due to its very strong antioxidant properties.},
  keywords = {*imported-from-citeulike-INRMM,~INRMM-MiD:c-13682861,aesculus-hippocastanum,forest-resources,medicinal-plants,secondary-production},
  number = {6}
}
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