Intensified tuberculosis treatment to reduce the mortality of HIV-infected and uninfected patients with tuberculosis meningitis (INTENSE-TBM): Study protocol for a Phase III Randomized Controlled Trial. Bonnet, F. Research Square, sep, 2022.
Intensified tuberculosis treatment to reduce the mortality of HIV-infected and uninfected patients with tuberculosis meningitis (INTENSE-TBM): Study protocol for a Phase III Randomized Controlled Trial [link]Paper  doi  abstract   bibtex   
Background: Tuberculous meningitis (TBM) is the most lethal and disabling form of tuberculosis (TB) particularly in sub-Saharan Africa. Current anti-TB treatment is poorly effective since TBM mortality reaches 40% in HIV negative patients and up to 70% in HIV co-infected patients. To reduce TBM induced morbidity and mortality, the INTENSE-TBM trial evaluates two
@article{Bonnet2022,
abstract = {Background: Tuberculous meningitis (TBM) is the most lethal and disabling form of tuberculosis (TB) particularly in sub-Saharan Africa. Current anti-TB treatment is poorly effective since TBM mortality reaches 40{\%} in HIV negative patients and up to 70{\%} in HIV co-infected patients. To reduce TBM induced morbidity and mortality, the INTENSE-TBM trial evaluates two},
author = {Bonnet, Fabrice},
doi = {10.21203/RS.3.RS-1941581/V1},
file = {:C$\backslash$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/Bonnet - 2022 - Intensified tuberculosis treatment to reduce the mortality of HIV-infected and uninfected patients with tuberculosis men.pdf:pdf},
journal = {Research Square},
keywords = {Aspirin,HIV,High-dose rifampicin,Linezolid,OA,Randomized Controlled Trial,Tuberculous meningitis,fund{\_}ack,protocol},
mendeley-tags = {OA,fund{\_}ack,protocol},
month = {sep},
pages = {doi.org/10.21203/rs.3.rs--1941581/v1},
title = {{Intensified tuberculosis treatment to reduce the mortality of HIV-infected and uninfected patients with tuberculosis meningitis (INTENSE-TBM): Study protocol for a Phase III Randomized Controlled Trial}},
url = {https://www.researchsquare.com https://www.researchsquare.com/article/rs-1941581/v1},
year = {2022}
}

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