@article{
 title = {Metabolic pathways promoting cancer cell survival and growth.},
 type = {article},
 year = {2015},
 identifiers = {[object Object]},
 keywords = {Animals,Cell Proliferation,Cell Survival,Energy Metabolism,Energy Metabolism: physiology,Glucose,Glucose: metabolism,Humans,Lipid Metabolism,Lipid Metabolism: physiology,Metabolic Networks and Pathways,Metabolic Networks and Pathways: physiology,Mice,Neoplasms,Neoplasms: metabolism,Oncogenes},
 pages = {351-9},
 volume = {17},
 websites = {http://www.ncbi.nlm.nih.gov/pubmed/25774832},
 month = {4},
 id = {0b2ae149-83f7-33f0-907e-5762ac098d62},
 created = {2016-04-27T01:09:21.000Z},
 accessed = {2015-11-05},
 file_attached = {false},
 profile_id = {95ad1c8a-ddc5-3572-ab20-1b5660ace0c4},
 group_id = {409b6953-b59c-338c-b6e7-a89d45a37162},
 last_modified = {2016-04-27T01:09:21.000Z},
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 abstract = {Activation of oncogenes and loss of tumour suppressors promote metabolic reprogramming in cancer, resulting in enhanced nutrient uptake to supply energetic and biosynthetic pathways. However, nutrient limitations within solid tumours may require that malignant cells exhibit metabolic flexibility to sustain growth and survival. Here, we highlight these adaptive mechanisms and also discuss emerging approaches to probe tumour metabolism in vivo and their potential to expand the metabolic repertoire of malignant cells even further.},
 bibtype = {article},
 author = {Boroughs, Lindsey K and DeBerardinis, Ralph J},
 journal = {Nature cell biology},
 number = {4}
}

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