Real-time monitoring of tissue displacement and temperature changes during MR-guided high intensity focused ultrasound: Monitoring of Changes During MRgHIFU. Bour, P., Marquet, F., Ozenne, V., Toupin, S., Dumont, E., Aubry, J., Lepetit-Coiffe, M., & Quesson, B. Magnetic Resonance in Medicine, 78(5):1911–1921, November, 2017. 25 citations (Crossref) [2023-04-12]![Real-time monitoring of tissue displacement and temperature changes during MR-guided high intensity focused ultrasound: Monitoring of Changes During MRgHIFU [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex Purpose: The therapy endpoint most commonly used in MRguided high intensity focused ultrasound is the thermal dose. Although namely correlated with nonviable tissue, it does not account for changes in mechanical properties of tissue during ablation. This study presents a new acquisition sequence for multislice, subsecond and simultaneous imaging of tissue temperature and displacement during ablation. Methods: A single-shot echo planar imaging sequence was implemented using a pair of motion-encoding gradients, with alternated polarities. A first ultrasound pulse was synchronized on the second lobe of the motion-encoding gradients and followed by continuous sonication to induce a local temperature increase in ex vivo muscle and in vivo on pig liver. Lastly, the method was evaluated in the brain of two volunteers to assess method’s precision. Results: For thermal doses higher than the lethal threshold, displacement amplitude was reduced by 21% and 28% at the focal point in muscle and liver, respectively. Displacement value remained nearly constant for nonlethal thermal doses values. The mean standard deviation of temperature and displacement in the brain of volunteers remained below 0.8 C and 2.5 mm. Conclusion: This new fast imaging sequence provides realtime measurement of temperature distribution and displacement at the focus during HIFU ablation. Magn Reson Med 000:000–000, 2017. VC 2017 International Society for Magnetic Resonance in Medicine.
@article{bour_real-time_2017,
title = {Real-time monitoring of tissue displacement and temperature changes during {MR}-guided high intensity focused ultrasound: {Monitoring} of {Changes} {During} {MRgHIFU}},
volume = {78},
issn = {07403194},
shorttitle = {Real-time monitoring of tissue displacement and temperature changes during {MR}-guided high intensity focused ultrasound},
url = {https://onlinelibrary.wiley.com/doi/10.1002/mrm.26588},
doi = {10.1002/mrm.26588},
abstract = {Purpose: The therapy endpoint most commonly used in MRguided high intensity focused ultrasound is the thermal dose. Although namely correlated with nonviable tissue, it does not account for changes in mechanical properties of tissue during ablation. This study presents a new acquisition sequence for multislice, subsecond and simultaneous imaging of tissue temperature and displacement during ablation.
Methods: A single-shot echo planar imaging sequence was implemented using a pair of motion-encoding gradients, with alternated polarities. A first ultrasound pulse was synchronized on the second lobe of the motion-encoding gradients and followed by continuous sonication to induce a local temperature increase in ex vivo muscle and in vivo on pig liver. Lastly, the method was evaluated in the brain of two volunteers to assess method’s precision.
Results: For thermal doses higher than the lethal threshold, displacement amplitude was reduced by 21\% and 28\% at the focal point in muscle and liver, respectively. Displacement value remained nearly constant for nonlethal thermal doses values. The mean standard deviation of temperature and displacement in the brain of volunteers remained below 0.8 C and 2.5 mm.
Conclusion: This new fast imaging sequence provides realtime measurement of temperature distribution and displacement at the focus during HIFU ablation. Magn Reson Med 000:000–000, 2017. VC 2017 International Society for Magnetic Resonance in Medicine.},
language = {en},
number = {5},
urldate = {2023-04-12},
journal = {Magnetic Resonance in Medicine},
author = {Bour, Pierre and Marquet, Fabrice and Ozenne, Valéry and Toupin, Solenn and Dumont, Erik and Aubry, Jean-François and Lepetit-Coiffe, Matthieu and Quesson, Bruno},
month = nov,
year = {2017},
note = {25 citations (Crossref) [2023-04-12]},
keywords = {ARFI, MRgHIFU, ablation, thermometry},
pages = {1911--1921},
}
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{"_id":"mSL3jW3m7X4M4sNzx","bibbaseid":"bour-marquet-ozenne-toupin-dumont-aubry-lepetitcoiffe-quesson-realtimemonitoringoftissuedisplacementandtemperaturechangesduringmrguidedhighintensityfocusedultrasoundmonitoringofchangesduringmrghifu-2017","author_short":["Bour, P.","Marquet, F.","Ozenne, V.","Toupin, S.","Dumont, E.","Aubry, J.","Lepetit-Coiffe, M.","Quesson, B."],"bibdata":{"bibtype":"article","type":"article","title":"Real-time monitoring of tissue displacement and temperature changes during MR-guided high intensity focused ultrasound: Monitoring of Changes During MRgHIFU","volume":"78","issn":"07403194","shorttitle":"Real-time monitoring of tissue displacement and temperature changes during MR-guided high intensity focused ultrasound","url":"https://onlinelibrary.wiley.com/doi/10.1002/mrm.26588","doi":"10.1002/mrm.26588","abstract":"Purpose: The therapy endpoint most commonly used in MRguided high intensity focused ultrasound is the thermal dose. Although namely correlated with nonviable tissue, it does not account for changes in mechanical properties of tissue during ablation. This study presents a new acquisition sequence for multislice, subsecond and simultaneous imaging of tissue temperature and displacement during ablation. Methods: A single-shot echo planar imaging sequence was implemented using a pair of motion-encoding gradients, with alternated polarities. A first ultrasound pulse was synchronized on the second lobe of the motion-encoding gradients and followed by continuous sonication to induce a local temperature increase in ex vivo muscle and in vivo on pig liver. Lastly, the method was evaluated in the brain of two volunteers to assess method’s precision. Results: For thermal doses higher than the lethal threshold, displacement amplitude was reduced by 21% and 28% at the focal point in muscle and liver, respectively. Displacement value remained nearly constant for nonlethal thermal doses values. The mean standard deviation of temperature and displacement in the brain of volunteers remained below 0.8 C and 2.5 mm. Conclusion: This new fast imaging sequence provides realtime measurement of temperature distribution and displacement at the focus during HIFU ablation. Magn Reson Med 000:000–000, 2017. VC 2017 International Society for Magnetic Resonance in Medicine.","language":"en","number":"5","urldate":"2023-04-12","journal":"Magnetic Resonance in Medicine","author":[{"propositions":[],"lastnames":["Bour"],"firstnames":["Pierre"],"suffixes":[]},{"propositions":[],"lastnames":["Marquet"],"firstnames":["Fabrice"],"suffixes":[]},{"propositions":[],"lastnames":["Ozenne"],"firstnames":["Valéry"],"suffixes":[]},{"propositions":[],"lastnames":["Toupin"],"firstnames":["Solenn"],"suffixes":[]},{"propositions":[],"lastnames":["Dumont"],"firstnames":["Erik"],"suffixes":[]},{"propositions":[],"lastnames":["Aubry"],"firstnames":["Jean-François"],"suffixes":[]},{"propositions":[],"lastnames":["Lepetit-Coiffe"],"firstnames":["Matthieu"],"suffixes":[]},{"propositions":[],"lastnames":["Quesson"],"firstnames":["Bruno"],"suffixes":[]}],"month":"November","year":"2017","note":"25 citations (Crossref) [2023-04-12]","keywords":"ARFI, MRgHIFU, ablation, thermometry","pages":"1911–1921","bibtex":"@article{bour_real-time_2017,\n\ttitle = {Real-time monitoring of tissue displacement and temperature changes during {MR}-guided high intensity focused ultrasound: {Monitoring} of {Changes} {During} {MRgHIFU}},\n\tvolume = {78},\n\tissn = {07403194},\n\tshorttitle = {Real-time monitoring of tissue displacement and temperature changes during {MR}-guided high intensity focused ultrasound},\n\turl = {https://onlinelibrary.wiley.com/doi/10.1002/mrm.26588},\n\tdoi = {10.1002/mrm.26588},\n\tabstract = {Purpose: The therapy endpoint most commonly used in MRguided high intensity focused ultrasound is the thermal dose. Although namely correlated with nonviable tissue, it does not account for changes in mechanical properties of tissue during ablation. This study presents a new acquisition sequence for multislice, subsecond and simultaneous imaging of tissue temperature and displacement during ablation.\nMethods: A single-shot echo planar imaging sequence was implemented using a pair of motion-encoding gradients, with alternated polarities. A first ultrasound pulse was synchronized on the second lobe of the motion-encoding gradients and followed by continuous sonication to induce a local temperature increase in ex vivo muscle and in vivo on pig liver. Lastly, the method was evaluated in the brain of two volunteers to assess method’s precision.\nResults: For thermal doses higher than the lethal threshold, displacement amplitude was reduced by 21\\% and 28\\% at the focal point in muscle and liver, respectively. Displacement value remained nearly constant for nonlethal thermal doses values. 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