@article{boussau_nonadaptive_nodate,
	title = {{NONADAPTIVE} {EVOLUTION} {OF} {MITOCHONDRIAL} {GENOME} {SIZE}},
	issn = {1558-5646},
	url = {http://onlinelibrary.wiley.com/doi/10.1111/j.1558-5646.2011.01322.x/abstract},
	doi = {10.1111/j.1558-5646.2011.01322.x},
	abstract = {Genomes vary greatly in size and complexity, and identifying the evolutionary forces that have generated this variation remains a major goal in biology. A controversial proposal is that most changes in genome size are initially deleterious and therefore are linked to episodes of decrease in effective population sizes. Support for this hypothesis comes from large-scale comparative analyses, but vanishes when phylogenetic nonindependence is taken into account. Another approach to test this hypothesis involves analyzing sequence evolution among clades where duplications have recently fixed. Here we show that episodes of fixation of duplications in mitochondrial genomes of the gecko Heteronotia binoei (2 independent clades) and of mantellid frogs (5 distinct branches) coincide with reductions in the ability of selection to purge slightly deleterious mutations. Our results support the idea that genome complexity can arise through nonadaptive processes in tetrapods.},
	language = {en},
	urldate = {2011-04-19TZ},
	journal = {Evolution},
	author = {Boussau, Bastien and Brown, Jeremy M and Fujita, Matthew K},
	keywords = {dn/ds, duplication, genome evolution, mantellid frogs, mitochondria, parthenogenetic lizards}
}

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