Progress and Current Trends in the Synthesis of Novel Polymers with Enhanced Mucoadhesive Properties. Brannigan, R. & Khutoryanskiy, V. Macromolecular Bioscience, 2019.
abstract   bibtex   
© 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Mucoadhesion is defined as the adherence of a synthetic or natural polymer to a mucosal membrane via physical or chemical interactions. Mucoadhesive materials are widely used to develop dosage forms for transmucosal drug delivery via ocular, nasal, esophageal, oral, vaginal, rectal, and intravesical routes of administration. This review will discuss some of the most prominent and recent synthetic methodologies employed to modify polymeric materials in order to enhance their mucoadhesive properties. This includes chemical conjugation of polymers with molecules bearing thiol-, catechol-, boronate-, acrylate-, methacrylate-, maleimide-, and N-hydroxy(sulfo)succinimide ester- groups.
@article{
 title = {Progress and Current Trends in the Synthesis of Novel Polymers with Enhanced Mucoadhesive Properties},
 type = {article},
 year = {2019},
 identifiers = {[object Object]},
 keywords = {Mucoadhesion,acrylate,catechol,maleimide,mucoadhesive polymers,thiomers,water-soluble polymers},
 volume = {19},
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 created = {2020-01-17T09:06:50.778Z},
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 abstract = {© 2019 WILEY-VCH Verlag GmbH  &  Co. KGaA, Weinheim Mucoadhesion is defined as the adherence of a synthetic or natural polymer to a mucosal membrane via physical or chemical interactions. Mucoadhesive materials are widely used to develop dosage forms for transmucosal drug delivery via ocular, nasal, esophageal, oral, vaginal, rectal, and intravesical routes of administration. This review will discuss some of the most prominent and recent synthetic methodologies employed to modify polymeric materials in order to enhance their mucoadhesive properties. This includes chemical conjugation of polymers with molecules bearing thiol-, catechol-, boronate-, acrylate-, methacrylate-, maleimide-, and N-hydroxy(sulfo)succinimide ester- groups.},
 bibtype = {article},
 author = {Brannigan, R.P. and Khutoryanskiy, V.V.},
 journal = {Macromolecular Bioscience},
 number = {10}
}

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