Probing transient non-native states in amyloid beta fiber elongation by NMR. Brender, J. R., Ghosh, A., Kotler, S. A., Krishnamoorthy, J., Bera, S., Morris, V., Sil, T. B., Garai, K., Reif, B., Bhunia, A., & Ramamoorthy, A. Chemical communications (Cambridge, England), 55(31):4483–4486, April, 2019. tex.ids= brenderProbingTransientNonnative2019 publisher: Royal Society of Chemistry
Probing transient non-native states in amyloid beta fiber elongation by NMR. [link]Paper  doi  abstract   bibtex   
Using NMR to probe transient binding of Aβ1-40 monomers to fibers, we find partially bound conformations with the highest degree of interaction near F19-K28 and a lesser degree of interaction near the C-terminus (L34-G37). This represents a shift away from the KLVFFA recognition sequence (residues 16-21) currently used for inhibitor design.
@article{Brender2019,
	title = {Probing transient non-native states in amyloid beta fiber elongation by {NMR}.},
	volume = {55},
	issn = {1364-548X},
	url = {http://www.ncbi.nlm.nih.gov/pubmed/30917192 http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC6544147},
	doi = {10.1039/c9cc01067j},
	abstract = {Using NMR to probe transient binding of Aβ1-40 monomers to fibers, we find partially bound conformations with the highest degree of interaction near F19-K28 and a lesser degree of interaction near the C-terminus (L34-G37). This represents a shift away from the KLVFFA recognition sequence (residues 16-21) currently used for inhibitor design.},
	number = {31},
	journal = {Chemical communications (Cambridge, England)},
	author = {Brender, Jeffrey R. and Ghosh, Anirban and Kotler, Samuel A. and Krishnamoorthy, Janarthanan and Bera, Swapna and Morris, Vanessa and Sil, Timir Baran and Garai, Kanchan and Reif, Bernd and Bhunia, Anirban and Ramamoorthy, Ayyalusamy},
	month = apr,
	year = {2019},
	pmid = {30917192},
	note = {tex.ids= brenderProbingTransientNonnative2019
publisher: Royal Society of Chemistry},
	pages = {4483--4486},
}

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