Molecular mechanism of genetic recombination in bacterial transformation. Bresler, S., Kreneva, R., Kushev, V., & Mosevitskií, M. Zeitschrift für Vererbungslehre, 95(3):288-297, Springer-Verlag, 1964. cited By 8
Molecular mechanism of genetic recombination in bacterial transformation [link]Paper  doi  abstract   bibtex   
B. subtilis cells auxotrophic for two linked markers (ind-his, ind-tyr, his-tyr) have been transformed by means of DNA preparations obtained by hybridization of wild type DNA with the DNA of a strain auxotrophic for one of the linked markers. It was established that hybridization does not increase the transforming activity of DNA for the heterozygous marker. A genetic analysis of the progeny of cells transformed by hybrid or wild type DNA was performed. On the basis of the data obtained a model of genetic recombination in transformation is proved. According to this model both strands of the donor DNA interact independently with the chromosome, and either strand can be incorporated into the cell genome with equal probability. According to the estimate made on the basis of this hypothesis, the probability of integration of a single DNA strand carrying a particular genetic marker is 8%. © 1964 Springer-Verlag.
@ARTICLE{Bresler1964288,
author={Bresler, S.E. and Kreneva, R.A. and Kushev, V.V. and Mosevitskií, M.I.},
title={Molecular mechanism of genetic recombination in bacterial transformation},
journal={Zeitschrift für Vererbungslehre},
year={1964},
volume={95},
number={3},
pages={288-297},
doi={10.1007/BF00897013},
note={cited By 8},
url={https://www.scopus.com/inward/record.uri?eid=2-s2.0-13344274558&doi=10.1007%2fBF00897013&partnerID=40&md5=677aa1725797318eb1550cd0ff40b995},
affiliation={Institute of High Molecular Weight Compounds of the Academy of Sciences of U.S.S.R., Lenmgrad, Russia},
abstract={B. subtilis cells auxotrophic for two linked markers (ind-his, ind-tyr, his-tyr) have been transformed by means of DNA preparations obtained by hybridization of wild type DNA with the DNA of a strain auxotrophic for one of the linked markers. It was established that hybridization does not increase the transforming activity of DNA for the heterozygous marker. A genetic analysis of the progeny of cells transformed by hybrid or wild type DNA was performed. On the basis of the data obtained a model of genetic recombination in transformation is proved. According to this model both strands of the donor DNA interact independently with the chromosome, and either strand can be incorporated into the cell genome with equal probability. According to the estimate made on the basis of this hypothesis, the probability of integration of a single DNA strand carrying a particular genetic marker is 8%. © 1964 Springer-Verlag.},
correspondence_address1={Bresler, S.E.; Institute of High Molecular Weight Compounds of the Academy of Sciences of U.S.S.R., Lenmgrad, Russia},
publisher={Springer-Verlag},
issn={16174615},
coden={MGGOA},
pubmed_id={14339939},
language={English},
abbrev_source_title={Mol. Genet. Genomics},
document_type={Article},
source={Scopus},
}

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