Epidemiology of chronic inflammatory demyelinating polyradiculoneuropathy in The Netherlands. Broers, M. C., de Wilde, M., Lingsma, H. F., van der Lei, J., Verhamme, K. M. C., & Jacobs, B. C. J Peripher Nerv Syst, 27(3):182-188, 2022. 1529-8027 Broers, Merel C Orcid: 0000-0002-7770-8475 de Wilde, Marcel Lingsma, Hester F van der Lei, Johan Verhamme, Katia M C Jacobs, Bart C Case Reports Research Support, Non-U.S. Gov't United States 2022/05/15 J Peripher Nerv Syst. 2022 Sep;27(3):182-188. doi: 10.1111/jns.12502. Epub 2022 May 29.abstract bibtex Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a rare but disabling disorder that often requires long-term immunomodulatory treatment. Background incidence rates and prevalence and risk factors for developing CIDP are still poorly defined. In the current study, we used a longitudinal population-based cohort study in The Netherlands to assess these rates and demographic factors and comorbidity associated with CIDP. We determined the incidence rate and prevalence of CIDP between 2008 and 2017 and the occurrence of potential risk factors in a retrospective Dutch cohort study using the Integrated Primary Care Information (IPCI) database. Cases were defined as CIDP if the diagnosis of CIDP was described in the electronic medical file. In a source population of 928 030 persons with a contributing follow-up of 3 525 686 person-years, we identified 65 patients diagnosed with CIDP. The overall incidence rate was 0.68 per 100 000 person-years (95% CI 0.45-0.99). The overall prevalence was 7.00 per 100 000 individuals (95% CI 5.41-8.93). The overall incidence rate was higher in men compared to woman (IRR 3.00, 95% CI 1.27-7.11), and higher in elderly of 50 years or older compared with people <50 years of age (IRR 17 95% CI 4-73). Twenty percent of CIDP cases had DM and 9% a co-existing other auto-immune disease. These background rates are important to monitor changes in the frequency of CIDP following infectious disease outbreaks, identify potential risk factors, and to estimate the social and economic burden of CIDP.
@article{RN277,
author = {Broers, M. C. and de Wilde, M. and Lingsma, H. F. and van der Lei, J. and Verhamme, K. M. C. and Jacobs, B. C.},
title = {Epidemiology of chronic inflammatory demyelinating polyradiculoneuropathy in The Netherlands},
journal = {J Peripher Nerv Syst},
volume = {27},
number = {3},
pages = {182-188},
note = {1529-8027 Broers, Merel C Orcid: 0000-0002-7770-8475 de Wilde, Marcel Lingsma, Hester F van der Lei, Johan Verhamme, Katia M C Jacobs, Bart C Case Reports Research Support, Non-U.S. Gov't United States 2022/05/15 J Peripher Nerv Syst. 2022 Sep;27(3):182-188. doi: 10.1111/jns.12502. Epub 2022 May 29.},
abstract = {Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a rare but disabling disorder that often requires long-term immunomodulatory treatment. Background incidence rates and prevalence and risk factors for developing CIDP are still poorly defined. In the current study, we used a longitudinal population-based cohort study in The Netherlands to assess these rates and demographic factors and comorbidity associated with CIDP. We determined the incidence rate and prevalence of CIDP between 2008 and 2017 and the occurrence of potential risk factors in a retrospective Dutch cohort study using the Integrated Primary Care Information (IPCI) database. Cases were defined as CIDP if the diagnosis of CIDP was described in the electronic medical file. In a source population of 928 030 persons with a contributing follow-up of 3 525 686 person-years, we identified 65 patients diagnosed with CIDP. The overall incidence rate was 0.68 per 100 000 person-years (95% CI 0.45-0.99). The overall prevalence was 7.00 per 100 000 individuals (95% CI 5.41-8.93). The overall incidence rate was higher in men compared to woman (IRR 3.00, 95% CI 1.27-7.11), and higher in elderly of 50 years or older compared with people <50 years of age (IRR 17 95% CI 4-73). Twenty percent of CIDP cases had DM and 9% a co-existing other auto-immune disease. These background rates are important to monitor changes in the frequency of CIDP following infectious disease outbreaks, identify potential risk factors, and to estimate the social and economic burden of CIDP.},
keywords = {Aged
Cohort Studies
Female
Humans
Incidence
Male
Netherlands/epidemiology
*Polyradiculoneuropathy, Chronic Inflammatory
Demyelinating/diagnosis/epidemiology
Retrospective Studies
Cidp
chronic inflammatory demyelinating polyradiculoneuropathy
epidemiology
prevalence ,
ISSN = 1085-9489 (Print) 1085-9489 ,
DOI = 10.1111/jns.12502},
year = {2022},
type = {Journal Article}
}
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Epub 2022 May 29.","abstract":"Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a rare but disabling disorder that often requires long-term immunomodulatory treatment. Background incidence rates and prevalence and risk factors for developing CIDP are still poorly defined. In the current study, we used a longitudinal population-based cohort study in The Netherlands to assess these rates and demographic factors and comorbidity associated with CIDP. We determined the incidence rate and prevalence of CIDP between 2008 and 2017 and the occurrence of potential risk factors in a retrospective Dutch cohort study using the Integrated Primary Care Information (IPCI) database. Cases were defined as CIDP if the diagnosis of CIDP was described in the electronic medical file. In a source population of 928 030 persons with a contributing follow-up of 3 525 686 person-years, we identified 65 patients diagnosed with CIDP. 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