Robust CT Synthesis for Radiotherapy Planning: Application to the Head & Neck Region

Robust CT Synthesis for Radiotherapy Planning: Application to the Head & Neck Region. Burgos, N., Cardoso, M J., Guerreiro, F., Veiga, C., Modat, M., McClelland, J., Knopf, A., Punwani, S., Atkinson, D., Arridge, S. R, Hutton, B. F, & Ourselin, S.
abstract bibtex

In this work, we propose to tackle the problem of magnetic resonance (MR)-based radiotherapy treatment planning in the head & neck area by synthesising computed tomography (CT) from MR images using an iterative multi-atlas approach. The proposed method relies on pre-acquired pairs of non-rigidly aligned T2-weighted MRI and CT images of the neck. To synthesise a pseudo CT, all the MRIs in the database are ﬁrst registered to the target MRI using a robust aﬃne followed by a deformable registration. An initial pseudo CT is obtained by fusing the mapped atlases according to their morphological similarity to the target. This initial pseudo CT is then combined with the target MR image in order to improve both the registration and fusion stages and reﬁne the synthesis in the bone region.

@article{burgos_robust_nodate,
	title = {Robust {CT} {Synthesis} for {Radiotherapy} {Planning}: {Application} to the {Head} \& {Neck} {Region}},
	abstract = {In this work, we propose to tackle the problem of magnetic resonance (MR)-based radiotherapy treatment planning in the head \& neck area by synthesising computed tomography (CT) from MR images using an iterative multi-atlas approach. The proposed method relies on pre-acquired pairs of non-rigidly aligned T2-weighted MRI and CT images of the neck. To synthesise a pseudo CT, all the MRIs in the database are ﬁrst registered to the target MRI using a robust aﬃne followed by a deformable registration. An initial pseudo CT is obtained by fusing the mapped atlases according to their morphological similarity to the target. This initial pseudo CT is then combined with the target MR image in order to improve both the registration and fusion stages and reﬁne the synthesis in the bone region.},
	language = {en},
	author = {Burgos, Ninon and Cardoso, M Jorge and Guerreiro, Filipa and Veiga, Catarina and Modat, Marc and McClelland, Jamie and Knopf, Antje-Christin and Punwani, Shonit and Atkinson, David and Arridge, Simon R and Hutton, Brian F and Ourselin, Sébastien},
	pages = {8},
}

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