@article{burgoyne_calcium_2015,
	title = {Calcium signaling at {ER} membrane contact sites},
	volume = {1853},
	issn = {0006-3002},
	doi = {10.1016/j.bbamcr.2015.01.022},
	abstract = {Communication between organelles is a necessary consequence of intracellular compartmentalization. Membrane contact sites (MCSs) are regions where the membranes of two organelles come into close apposition allowing exchange of small molecules and ions including Ca²⁺. The ER, the cell's major Ca²⁺ store, forms an extensive and dynamic network of contacts with multiple organelles. Here we review established and emerging roles of ER contacts as platforms for Ca²⁺ exchange and further consider a potential role for Ca²⁺ in the regulation of MCS formation. We additionally discuss the challenges associated with the study of MCS biology and highlight advances in microscopy-based solutions. This article is part of a Special Issue entitled: 13th European Symposium on Calcium.},
	language = {eng},
	number = {9},
	journal = {Biochimica Et Biophysica Acta},
	author = {Burgoyne, Thomas and Patel, Sandip and Eden, Emily R.},
	month = sep,
	year = {2015},
	pmid = {25662816},
	keywords = {Animals, Ca2+ exchange, Calcium, Calcium Signaling, ER, Endoplasmic Reticulum, Humans, Intracellular Membranes, Membrane contact sites (MCSs)},
	pages = {2012--2017}
}

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