Human renal cancer stem cells. Bussolati, B., Dekel, B., Azzarone, B., & Camussi, G. Cancer Lett, 2012.
Paper doi abstract bibtex Cancer stem cells (CSCs), isolated in renal carcinomas, exhibit tumor-initiating capabilities and pluripotency. No specific CSC markers have been identified so far; therefore, their characterization is mainly based on functional studies. As they are resistant to chemo and radio therapy, renal CSCs may have a relevant role in tumor establishment, progression, and recurrence. CSCs were also shown to contribute to intra-tumor vasculogenesis through an endothelial differentiation and to favor the generation of the pre-metastatic niche through the release of exosomes/microvesicles.
@article{bussolati_human_2012,
title = {Human renal cancer stem cells},
issn = {1872-7980 (ELECTRONIC) 0304-3835 (LINKING)},
url = {http://www.ncbi.nlm.nih.gov/pubmed/22587951},
doi = {10.1016/j.canlet.2012.05.007},
abstract = {Cancer stem cells (CSCs), isolated in renal carcinomas, exhibit tumor-initiating capabilities and pluripotency. No specific CSC markers have been identified so far; therefore, their characterization is mainly based on functional studies. As they are resistant to chemo and radio therapy, renal CSCs may have a relevant role in tumor establishment, progression, and recurrence. CSCs were also shown to contribute to intra-tumor vasculogenesis through an endothelial differentiation and to favor the generation of the pre-metastatic niche through the release of exosomes/microvesicles.},
journal = {Cancer Lett},
author = {Bussolati, B. and Dekel, B. and Azzarone, B. and Camussi, G.},
year = {2012},
}
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