@article{calvo_successful_2021,
	title = {Successful deprescribing of proton pump inhibitors with a patient-centered process: the {DESPIBP} {Project}},
	volume = {77},
	copyright = {Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC-BY-NC-ND)},
	issn = {0031-6970, 1432-1041},
	shorttitle = {Successful deprescribing of proton pump inhibitors with a patient-centered process},
	url = {https://link.springer.com/10.1007/s00228-021-03186-x},
	doi = {10.1007/s00228-021-03186-x},
	abstract = {Background  Proton-pump inhibitors (PPIs) are among the most frequently prescribed drugs, but they are being overprescribed.
Objective  To evaluate the applicability of a deprescription algorithm in hospitalized patients with chronic PPI use.
Methods  A prospective study including consecutive gastroenterology department hospitalized patients with chronic PPI use. The prescription was reassessed and a deprescribing algorithm was applied. Follow-up was carried out at 4, 12, and 24 weeks.
Results  A total of 513 (44.22\%) of 1160 had chronic PPI use; 371 met inclusion criteria and were evaluated: 285 (76.82\%) with appropriate prescription and 86 (23.18\%) with inappropriate, mainly (52.30\%) due to polypharmacy. Seventy-five patients accepted the deprescribing process. Sixty-one (81.33\%) maintained deprescription at week 4, 56 (74.66\%) at week 12, and 54 (72.00\%) at week 24. Eleven of 21 restarted the PPI because of symptoms. No differences were found between the successful deprescription group and the unsuccessful one, regarding sex (p = 0.877), age (p = 0.635), PPI indication (p = 0.663), or deprescription regimen (p = 0.805). No patient had any adverse event attributable to deprescription.
Conclusion  There is a high inappropriate indication for PPIs in patients admitted to the gastroenterology department. The application of a patient-centered deprescribing algorithm is a safe and effective strategy to reduce their inappropriate consumption in the medium term.},
	language = {en},
	number = {12},
	urldate = {2025-01-07},
	journal = {European Journal of Clinical Pharmacology},
	author = {Calvo, Lamuela L. J. and García Cámara, P. and Llorente Barrio, M. and Sierra Gabarda, O. and Monzón Baez, R. and Arbonés Mainar, J. M. and Alcedo González, J. and Bernal Monterde, V.},
	month = dec,
	year = {2021},
	pages = {1927--1933},
	url_paper={https://api.zotero.org/users/9838054/publications/items/T6JI2N8K/file/view}
}

{"_id":"ZRZuTyKNH97aQyAAZ","bibbaseid":"calvo-garcacmara-llorentebarrio-sierragabarda-monznbaez-arbonsmainar-alcedogonzlez-bernalmonterde-successfuldeprescribingofprotonpumpinhibitorswithapatientcenteredprocessthedespibpproject-2021","author_short":["Calvo, L. L. J.","García Cámara, P.","Llorente Barrio, M.","Sierra Gabarda, O.","Monzón Baez, R.","Arbonés Mainar, J. M.","Alcedo González, J.","Bernal Monterde, V."],"bibdata":{"bibtype":"article","type":"article","title":"Successful deprescribing of proton pump inhibitors with a patient-centered process: the DESPIBP Project","volume":"77","copyright":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC-BY-NC-ND)","issn":"0031-6970, 1432-1041","shorttitle":"Successful deprescribing of proton pump inhibitors with a patient-centered process","url":"https://link.springer.com/10.1007/s00228-021-03186-x","doi":"10.1007/s00228-021-03186-x","abstract":"Background  Proton-pump inhibitors (PPIs) are among the most frequently prescribed drugs, but they are being overprescribed. Objective  To evaluate the applicability of a deprescription algorithm in hospitalized patients with chronic PPI use. Methods  A prospective study including consecutive gastroenterology department hospitalized patients with chronic PPI use. The prescription was reassessed and a deprescribing algorithm was applied. Follow-up was carried out at 4, 12, and 24 weeks. Results  A total of 513 (44.22%) of 1160 had chronic PPI use; 371 met inclusion criteria and were evaluated: 285 (76.82%) with appropriate prescription and 86 (23.18%) with inappropriate, mainly (52.30%) due to polypharmacy. Seventy-five patients accepted the deprescribing process. Sixty-one (81.33%) maintained deprescription at week 4, 56 (74.66%) at week 12, and 54 (72.00%) at week 24. Eleven of 21 restarted the PPI because of symptoms. No differences were found between the successful deprescription group and the unsuccessful one, regarding sex (p = 0.877), age (p = 0.635), PPI indication (p = 0.663), or deprescription regimen (p = 0.805). No patient had any adverse event attributable to deprescription. Conclusion  There is a high inappropriate indication for PPIs in patients admitted to the gastroenterology department. The application of a patient-centered deprescribing algorithm is a safe and effective strategy to reduce their inappropriate consumption in the medium term.","language":"en","number":"12","urldate":"2025-01-07","journal":"European Journal of Clinical Pharmacology","author":[{"propositions":[],"lastnames":["Calvo"],"firstnames":["Lamuela","L.","J."],"suffixes":[]},{"propositions":[],"lastnames":["García","Cámara"],"firstnames":["P."],"suffixes":[]},{"propositions":[],"lastnames":["Llorente","Barrio"],"firstnames":["M."],"suffixes":[]},{"propositions":[],"lastnames":["Sierra","Gabarda"],"firstnames":["O."],"suffixes":[]},{"propositions":[],"lastnames":["Monzón","Baez"],"firstnames":["R."],"suffixes":[]},{"propositions":[],"lastnames":["Arbonés","Mainar"],"firstnames":["J.","M."],"suffixes":[]},{"propositions":[],"lastnames":["Alcedo","González"],"firstnames":["J."],"suffixes":[]},{"propositions":[],"lastnames":["Bernal","Monterde"],"firstnames":["V."],"suffixes":[]}],"month":"December","year":"2021","pages":"1927–1933","url_paper":"https://api.zotero.org/users/9838054/publications/items/T6JI2N8K/file/view","bibtex":"@article{calvo_successful_2021,\n\ttitle = {Successful deprescribing of proton pump inhibitors with a patient-centered process: the {DESPIBP} {Project}},\n\tvolume = {77},\n\tcopyright = {Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC-BY-NC-ND)},\n\tissn = {0031-6970, 1432-1041},\n\tshorttitle = {Successful deprescribing of proton pump inhibitors with a patient-centered process},\n\turl = {https://link.springer.com/10.1007/s00228-021-03186-x},\n\tdoi = {10.1007/s00228-021-03186-x},\n\tabstract = {Background  Proton-pump inhibitors (PPIs) are among the most frequently prescribed drugs, but they are being overprescribed.\nObjective  To evaluate the applicability of a deprescription algorithm in hospitalized patients with chronic PPI use.\nMethods  A prospective study including consecutive gastroenterology department hospitalized patients with chronic PPI use. The prescription was reassessed and a deprescribing algorithm was applied. Follow-up was carried out at 4, 12, and 24 weeks.\nResults  A total of 513 (44.22\\%) of 1160 had chronic PPI use; 371 met inclusion criteria and were evaluated: 285 (76.82\\%) with appropriate prescription and 86 (23.18\\%) with inappropriate, mainly (52.30\\%) due to polypharmacy. Seventy-five patients accepted the deprescribing process. Sixty-one (81.33\\%) maintained deprescription at week 4, 56 (74.66\\%) at week 12, and 54 (72.00\\%) at week 24. Eleven of 21 restarted the PPI because of symptoms. No differences were found between the successful deprescription group and the unsuccessful one, regarding sex (p = 0.877), age (p = 0.635), PPI indication (p = 0.663), or deprescription regimen (p = 0.805). No patient had any adverse event attributable to deprescription.\nConclusion  There is a high inappropriate indication for PPIs in patients admitted to the gastroenterology department. The application of a patient-centered deprescribing algorithm is a safe and effective strategy to reduce their inappropriate consumption in the medium term.},\n\tlanguage = {en},\n\tnumber = {12},\n\turldate = {2025-01-07},\n\tjournal = {European Journal of Clinical Pharmacology},\n\tauthor = {Calvo, Lamuela L. J. and García Cámara, P. and Llorente Barrio, M. and Sierra Gabarda, O. and Monzón Baez, R. and Arbonés Mainar, J. M. and Alcedo González, J. and Bernal Monterde, V.},\n\tmonth = dec,\n\tyear = {2021},\n\tpages = {1927--1933},\n\turl_paper={https://api.zotero.org/users/9838054/publications/items/T6JI2N8K/file/view}\n}\n\n\n\n\n\n\n\n","author_short":["Calvo, L. L. J.","García Cámara, P.","Llorente Barrio, M.","Sierra Gabarda, O.","Monzón Baez, R.","Arbonés Mainar, J. M.","Alcedo González, J.","Bernal Monterde, V."],"key":"calvo_successful_2021","id":"calvo_successful_2021","bibbaseid":"calvo-garcacmara-llorentebarrio-sierragabarda-monznbaez-arbonsmainar-alcedogonzlez-bernalmonterde-successfuldeprescribingofprotonpumpinhibitorswithapatientcenteredprocessthedespibpproject-2021","role":"author","urls":{"Paper":"https://link.springer.com/10.1007/s00228-021-03186-x"," paper":"https://api.zotero.org/users/9838054/publications/items/T6JI2N8K/file/view"},"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://bibbase.org/zotero-mypublications/arbones","dataSources":["HYaQtBq73JSgvuWz5","xCmxkYoGpgE4G7Fj6"],"keywords":[],"search_terms":["successful","deprescribing","proton","pump","inhibitors","patient","centered","process","despibp","project","calvo","garcía cámara","llorente barrio","sierra gabarda","monzón baez","arbonés mainar","alcedo gonzález","bernal monterde"],"title":"Successful deprescribing of proton pump inhibitors with a patient-centered process: the DESPIBP Project","year":2021}