Clinical Effects of Heliox Administration for Acute Bronchiolitis in Young Infants. Cambonie, G., Milési, C., Fournier-Favre, S., Counil, F., Jaber, S., Picaud, J., & Matecki, S. Chest, 129(3):676–682, March, 2006. ![Clinical Effects of Heliox Administration for Acute Bronchiolitis in Young Infants [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex Objective:To assess the effect of heliox, a helium-oxygen mixture, on respiratory distress symptoms in young infants.Design:Prospective, randomized, double-blind study.Setting:Pediatric ICU (PICU) of a university hospital.Patients:Twenty infants, all \textless 3 months old, admitted to the PICU with moderate-to-severe acute respiratory syncytial virus bronchiolitis.Interventions:All infants were randomly and blindly assigned to inhale either heliox or an air-oxygen mixture (airox) for 1 h under an oxyhood.Measurements and results:After 1 h, the respiratory distress score was significantly lower in the heliox group compared with the airox group (3.05 vs 5.5, p \textless 0.01), with a significant reduction in accessory muscles use (p \textless 0.05) and expiratory wheezing (p \textless 0.01). In contrast, inspiratory breath sounds and cyanosis did not significantly differ between groups. The ex-premature infants of the heliox group had a higher respiratory distress score at baseline compared with the term infants of this group (5.8 vs 5.2, p \textless 0.05) and a comparable decrease in the score at 60 min.Conclusions:In young infants, even those born prematurely, heliox breathing induced a rapid reduction in accessory muscles use and expiratory wheezing. Further studies are needed to confirm the decreased respiratory muscle work of breathing during heliox inhalation in this population.
@article{cambonie_clinical_2006,
title = {Clinical {Effects} of {Heliox} {Administration} for {Acute} {Bronchiolitis} in {Young} {Infants}},
volume = {129},
issn = {0012-3692},
url = {http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=16537867&retmode=ref&cmd=prlinks},
doi = {10.1378/chest.129.3.676},
abstract = {Objective:To assess the effect of heliox, a helium-oxygen mixture, on respiratory distress symptoms in young infants.Design:Prospective, randomized, double-blind study.Setting:Pediatric ICU (PICU) of a university hospital.Patients:Twenty infants, all {\textless} 3 months old, admitted to the PICU with moderate-to-severe acute respiratory syncytial virus bronchiolitis.Interventions:All infants were randomly and blindly assigned to inhale either heliox or an air-oxygen mixture (airox) for 1 h under an oxyhood.Measurements and results:After 1 h, the respiratory distress score was significantly lower in the heliox group compared with the airox group (3.05 vs 5.5, p {\textless} 0.01), with a significant reduction in accessory muscles use (p {\textless} 0.05) and expiratory wheezing (p {\textless} 0.01). In contrast, inspiratory breath sounds and cyanosis did not significantly differ between groups. The ex-premature infants of the heliox group had a higher respiratory distress score at baseline compared with the term infants of this group (5.8 vs 5.2, p {\textless} 0.05) and a comparable decrease in the score at 60 min.Conclusions:In young infants, even those born prematurely, heliox breathing induced a rapid reduction in accessory muscles use and expiratory wheezing. Further studies are needed to confirm the decreased respiratory muscle work of breathing during heliox inhalation in this population.},
number = {3},
journal = {Chest},
author = {Cambonie, Gilles and Milési, Christophe and Fournier-Favre, Sébastien and Counil, Franċois and Jaber, Samir and Picaud, Jean-Charles and Matecki, Stefan},
month = mar,
year = {2006},
pages = {676--682},
}
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In contrast, inspiratory breath sounds and cyanosis did not significantly differ between groups. The ex-premature infants of the heliox group had a higher respiratory distress score at baseline compared with the term infants of this group (5.8 vs 5.2, p \\textless 0.05) and a comparable decrease in the score at 60 min.Conclusions:In young infants, even those born prematurely, heliox breathing induced a rapid reduction in accessory muscles use and expiratory wheezing. Further studies are needed to confirm the decreased respiratory muscle work of breathing during heliox inhalation in this population.","number":"3","journal":"Chest","author":[{"propositions":[],"lastnames":["Cambonie"],"firstnames":["Gilles"],"suffixes":[]},{"propositions":[],"lastnames":["Milési"],"firstnames":["Christophe"],"suffixes":[]},{"propositions":[],"lastnames":["Fournier-Favre"],"firstnames":["Sébastien"],"suffixes":[]},{"propositions":[],"lastnames":["Counil"],"firstnames":["Franċois"],"suffixes":[]},{"propositions":[],"lastnames":["Jaber"],"firstnames":["Samir"],"suffixes":[]},{"propositions":[],"lastnames":["Picaud"],"firstnames":["Jean-Charles"],"suffixes":[]},{"propositions":[],"lastnames":["Matecki"],"firstnames":["Stefan"],"suffixes":[]}],"month":"March","year":"2006","pages":"676–682","bibtex":"@article{cambonie_clinical_2006,\n\ttitle = {Clinical {Effects} of {Heliox} {Administration} for {Acute} {Bronchiolitis} in {Young} {Infants}},\n\tvolume = {129},\n\tissn = {0012-3692},\n\turl = {http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=16537867&retmode=ref&cmd=prlinks},\n\tdoi = {10.1378/chest.129.3.676},\n\tabstract = {Objective:To assess the effect of heliox, a helium-oxygen mixture, on respiratory distress symptoms in young infants.Design:Prospective, randomized, double-blind study.Setting:Pediatric ICU (PICU) of a university hospital.Patients:Twenty infants, all {\\textless} 3 months old, admitted to the PICU with moderate-to-severe acute respiratory syncytial virus bronchiolitis.Interventions:All infants were randomly and blindly assigned to inhale either heliox or an air-oxygen mixture (airox) for 1 h under an oxyhood.Measurements and results:After 1 h, the respiratory distress score was significantly lower in the heliox group compared with the airox group (3.05 vs 5.5, p {\\textless} 0.01), with a significant reduction in accessory muscles use (p {\\textless} 0.05) and expiratory wheezing (p {\\textless} 0.01). In contrast, inspiratory breath sounds and cyanosis did not significantly differ between groups. The ex-premature infants of the heliox group had a higher respiratory distress score at baseline compared with the term infants of this group (5.8 vs 5.2, p {\\textless} 0.05) and a comparable decrease in the score at 60 min.Conclusions:In young infants, even those born prematurely, heliox breathing induced a rapid reduction in accessory muscles use and expiratory wheezing. Further studies are needed to confirm the decreased respiratory muscle work of breathing during heliox inhalation in this population.},\n\tnumber = {3},\n\tjournal = {Chest},\n\tauthor = {Cambonie, Gilles and Milési, Christophe and Fournier-Favre, Sébastien and Counil, Franċois and Jaber, Samir and Picaud, Jean-Charles and Matecki, Stefan},\n\tmonth = mar,\n\tyear = {2006},\n\tpages = {676--682},\n}\n\n\n\n","author_short":["Cambonie, G.","Milési, C.","Fournier-Favre, S.","Counil, F.","Jaber, S.","Picaud, J.","Matecki, S."],"key":"cambonie_clinical_2006","id":"cambonie_clinical_2006","bibbaseid":"cambonie-milsi-fournierfavre-counil-jaber-picaud-matecki-clinicaleffectsofhelioxadministrationforacutebronchiolitisinyounginfants-2006","role":"author","urls":{"Paper":"http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=16537867&retmode=ref&cmd=prlinks"},"metadata":{"authorlinks":{}},"downloads":0,"html":""},"search_terms":["clinical","effects","heliox","administration","acute","bronchiolitis","young","infants","cambonie","milési","fournier-favre","counil","jaber","picaud","matecki"],"keywords":[],"authorIDs":[],"dataSources":["4P4hKw3sZj97Zz2kx"]}