@article{RN92,
   author = {Campana, L. G. and Daud, A. and Lancellotti, F. and Arroyo, J. P. and Davalos, R. V. and Di Prata, C. and Gehl, J.},
   title = {Pulsed Electric Fields in Oncology: A Snapshot of Current Clinical Practices and Research Directions from the 4th World Congress of Electroporation},
   journal = {Cancers (Basel)},
   volume = {15},
   number = {13},
   note = {2072-6694
Campana, Luca G
Orcid: 0000-0002-8466-8459
Daud, Adil
Lancellotti, Francesco
Orcid: 0000-0002-1830-127x
Arroyo, Julio P
Orcid: 0000-0003-4690-6337
Davalos, Rafael V
Orcid: 0000-0003-1503-9509
Di Prata, Claudia
Gehl, Julie
Orcid: 0000-0003-3829-0210
R25 GM072767/GM/NIGMS NIH HHS/United States
Journal Article
Review
Switzerland
2023/07/14
Cancers (Basel). 2023 Jun 25;15(13):3340. doi: 10.3390/cancers15133340.},
   abstract = {The 4th World Congress of Electroporation (Copenhagen, 9-13 October 2022) provided a unique opportunity to convene leading experts in pulsed electric fields (PEF). PEF-based therapies harness electric fields to produce therapeutically useful effects on cancers and represent a valuable option for a variety of patients. As such, irreversible electroporation (IRE), gene electrotransfer (GET), electrochemotherapy (ECT), calcium electroporation (Ca-EP), and tumour-treating fields (TTF) are on the rise. Still, their full therapeutic potential remains underappreciated, and the field faces fragmentation, as shown by parallel maturation and differences in the stages of development and regulatory approval worldwide. This narrative review provides a glimpse of PEF-based techniques, including key mechanisms, clinical indications, and advances in therapy; finally, it offers insights into current research directions. By highlighting a common ground, the authors aim to break silos, strengthen cross-functional collaboration, and pave the way to novel possibilities for intervention. Intriguingly, beyond their peculiar mechanism of action, PEF-based therapies share technical interconnections and multifaceted biological effects (e.g., vascular, immunological) worth exploiting in combinatorial strategies.},
   keywords = {cancer
electrochemotherapy
electroporation
gene electrotransfer
irreversible electroporation
quality of life
tumour-treating fields},
   ISSN = {2072-6694 (Print)
2072-6694},
   DOI = {10.3390/cancers15133340},
   year = {2023},
   type = {Journal Article}
}

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V.","Di Prata, C.","Gehl, J."],"bibdata":{"bibtype":"article","type":"Journal Article","author":[{"propositions":[],"lastnames":["Campana"],"firstnames":["L.","G."],"suffixes":[]},{"propositions":[],"lastnames":["Daud"],"firstnames":["A."],"suffixes":[]},{"propositions":[],"lastnames":["Lancellotti"],"firstnames":["F."],"suffixes":[]},{"propositions":[],"lastnames":["Arroyo"],"firstnames":["J.","P."],"suffixes":[]},{"propositions":[],"lastnames":["Davalos"],"firstnames":["R.","V."],"suffixes":[]},{"propositions":[],"lastnames":["Di","Prata"],"firstnames":["C."],"suffixes":[]},{"propositions":[],"lastnames":["Gehl"],"firstnames":["J."],"suffixes":[]}],"title":"Pulsed Electric Fields in Oncology: A Snapshot of Current Clinical Practices and Research Directions from the 4th World Congress of Electroporation","journal":"Cancers (Basel)","volume":"15","number":"13","note":"2072-6694 Campana, Luca G Orcid: 0000-0002-8466-8459 Daud, Adil Lancellotti, Francesco Orcid: 0000-0002-1830-127x Arroyo, Julio P Orcid: 0000-0003-4690-6337 Davalos, Rafael V Orcid: 0000-0003-1503-9509 Di Prata, Claudia Gehl, Julie Orcid: 0000-0003-3829-0210 R25 GM072767/GM/NIGMS NIH HHS/United States Journal Article Review Switzerland 2023/07/14 Cancers (Basel). 2023 Jun 25;15(13):3340. doi: 10.3390/cancers15133340.","abstract":"The 4th World Congress of Electroporation (Copenhagen, 9-13 October 2022) provided a unique opportunity to convene leading experts in pulsed electric fields (PEF). PEF-based therapies harness electric fields to produce therapeutically useful effects on cancers and represent a valuable option for a variety of patients. As such, irreversible electroporation (IRE), gene electrotransfer (GET), electrochemotherapy (ECT), calcium electroporation (Ca-EP), and tumour-treating fields (TTF) are on the rise. Still, their full therapeutic potential remains underappreciated, and the field faces fragmentation, as shown by parallel maturation and differences in the stages of development and regulatory approval worldwide. This narrative review provides a glimpse of PEF-based techniques, including key mechanisms, clinical indications, and advances in therapy; finally, it offers insights into current research directions. By highlighting a common ground, the authors aim to break silos, strengthen cross-functional collaboration, and pave the way to novel possibilities for intervention. Intriguingly, beyond their peculiar mechanism of action, PEF-based therapies share technical interconnections and multifaceted biological effects (e.g., vascular, immunological) worth exploiting in combinatorial strategies.","keywords":"cancer electrochemotherapy electroporation gene electrotransfer irreversible electroporation quality of life tumour-treating fields","issn":"2072-6694 (Print) 2072-6694","doi":"10.3390/cancers15133340","year":"2023","bibtex":"@article{RN92,\n author = {Campana, L. G. and Daud, A. and Lancellotti, F. and Arroyo, J. P. and Davalos, R. V. and Di Prata, C. and Gehl, J.},\n title = {Pulsed Electric Fields in Oncology: A Snapshot of Current Clinical Practices and Research Directions from the 4th World Congress of Electroporation},\n journal = {Cancers (Basel)},\n volume = {15},\n number = {13},\n note = {2072-6694\nCampana, Luca G\nOrcid: 0000-0002-8466-8459\nDaud, Adil\nLancellotti, Francesco\nOrcid: 0000-0002-1830-127x\nArroyo, Julio P\nOrcid: 0000-0003-4690-6337\nDavalos, Rafael V\nOrcid: 0000-0003-1503-9509\nDi Prata, Claudia\nGehl, Julie\nOrcid: 0000-0003-3829-0210\nR25 GM072767/GM/NIGMS NIH HHS/United States\nJournal Article\nReview\nSwitzerland\n2023/07/14\nCancers (Basel). 2023 Jun 25;15(13):3340. doi: 10.3390/cancers15133340.},\n abstract = {The 4th World Congress of Electroporation (Copenhagen, 9-13 October 2022) provided a unique opportunity to convene leading experts in pulsed electric fields (PEF). PEF-based therapies harness electric fields to produce therapeutically useful effects on cancers and represent a valuable option for a variety of patients. As such, irreversible electroporation (IRE), gene electrotransfer (GET), electrochemotherapy (ECT), calcium electroporation (Ca-EP), and tumour-treating fields (TTF) are on the rise. Still, their full therapeutic potential remains underappreciated, and the field faces fragmentation, as shown by parallel maturation and differences in the stages of development and regulatory approval worldwide. This narrative review provides a glimpse of PEF-based techniques, including key mechanisms, clinical indications, and advances in therapy; finally, it offers insights into current research directions. By highlighting a common ground, the authors aim to break silos, strengthen cross-functional collaboration, and pave the way to novel possibilities for intervention. 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