Recent Advancements in Electroporation Technologies: From Bench to Clinic. Campelo, S. N., Huang, P. H., Buie, C. R., & Davalos, R. V. Annu Rev Biomed Eng, 25:77-100, 2023. 1545-4274 Campelo, Sabrina N Huang, Po-Hsun Buie, Cullen R Davalos, Rafael V P01 CA207206/CA/NCI NIH HHS/United States RM1 GM135102/GM/NIGMS NIH HHS/United States Journal Article Research Support, N.I.H., Extramural Review United States 2023/03/01 Annu Rev Biomed Eng. 2023 Jun 8;25:77-100. doi: 10.1146/annurev-bioeng-110220-023800. Epub 2023 Feb 28.
doi  abstract   bibtex   
Over the past decade, the increased adoption of electroporation-based technologies has led to an expansion of clinical research initiatives. Electroporation has been utilized in molecular biology for mammalian and bacterial transfection; for food sanitation; and in therapeutic settings to increase drug uptake, for gene therapy, and to eliminate cancerous tissues. We begin this article by discussing the biophysics required for understanding the concepts behind the cell permeation phenomenon that is electroporation. We then review nano- and microscale single-cell electroporation technologies before scaling up to emerging in vivo applications.
@article{RN97,
   author = {Campelo, S. N. and Huang, P. H. and Buie, C. R. and Davalos, R. V.},
   title = {Recent Advancements in Electroporation Technologies: From Bench to Clinic},
   journal = {Annu Rev Biomed Eng},
   volume = {25},
   pages = {77-100},
   note = {1545-4274
Campelo, Sabrina N
Huang, Po-Hsun
Buie, Cullen R
Davalos, Rafael V
P01 CA207206/CA/NCI NIH HHS/United States
RM1 GM135102/GM/NIGMS NIH HHS/United States
Journal Article
Research Support, N.I.H., Extramural
Review
United States
2023/03/01
Annu Rev Biomed Eng. 2023 Jun 8;25:77-100. doi: 10.1146/annurev-bioeng-110220-023800. Epub 2023 Feb 28.},
   abstract = {Over the past decade, the increased adoption of electroporation-based technologies has led to an expansion of clinical research initiatives. Electroporation has been utilized in molecular biology for mammalian and bacterial transfection; for food sanitation; and in therapeutic settings to increase drug uptake, for gene therapy, and to eliminate cancerous tissues. We begin this article by discussing the biophysics required for understanding the concepts behind the cell permeation phenomenon that is electroporation. We then review nano- and microscale single-cell electroporation technologies before scaling up to emerging in vivo applications.},
   keywords = {Animals
Humans
Electroporation
Transfection
*Neoplasms/therapy
Electroporation Therapies
Genetic Therapy
*Electrochemotherapy
Mammals
electrochemotherapy
gene therapy
microfluidics
pulsed field ablation},
   ISSN = {1523-9829},
   DOI = {10.1146/annurev-bioeng-110220-023800},
   year = {2023},
   type = {Journal Article}
}

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