The baseline characteristics and interim analyses of the high-risk sentinel cohort of the Vietnam Initiative on Zoonotic InfectiONS (VIZIONS). Carrique-Mas, J. J., Tue, N. T., Bryant, J. E., Saylors, K., Cuong, N. V., Hoa, N. T., An, N. N., Hien, V. B., Lao, P. V., Tu, N. C., Chuyen, N. K., Chuc, N. T. K., Tan, D. V., Duong, H. V. V., Toan, T. K., Chi, N. T. Y., Campbell, J., Rabaa, M. A., Nadjm, B., Woolhouse, M., Wertheim, H., Thwaites, G., & Baker, S. Scientific reports, 5:17965, December, 2015.
doi  abstract   bibtex   
The Vietnam Initiative for Zoonotic Infections (VIZIONS) includes community-based 'high-risk sentinel cohort' (HRSC) studies investigating individuals at risk of zoonotic infection due to occupational or residential exposure to animals. A total of 852 HRSC members were recruited between March 2013 and August 2014 from three provinces (Ha Noi, Dak Lak, and Dong Thap). The most numerous group (72.8%) corresponded to individuals living on farms, followed by slaughterers (16.3%) and animal health workers (8.5%). Nasal/pharyngeal and rectal swabs were collected from HRSC members at recruitment and after notifying illness. Exposure to exotic animals (including wild pigs, porcupine, monkey, civet, bamboo rat and bat) was highest for the Dak Lak cohort (53.7%), followed by Ha Noi (13.7%) and Dong Thap (4.0%). A total of 26.8% of individuals reported consumption of raw blood over the previous year; 33.6% slaughterers reported no use of protective equipment at work. Over 686 person-years of observation, 213 episodes of suspect infectious disease were notified, equivalent of 0.35 reports per person-year. Responsive samples were collected from animals in the farm cohort. There was noticeable time and space clustering of disease episodes suggesting that the VIZIONS set up is also suitable for the formal epidemiological investigation of disease outbreaks.
@article{carrique-mas_baseline_2015,
	title = {The baseline characteristics and interim analyses of the high-risk sentinel cohort of the {Vietnam} {Initiative} on {Zoonotic} {InfectiONS} ({VIZIONS}).},
	volume = {5},
	issn = {2045-2322 2045-2322},
	doi = {10.1038/srep17965},
	abstract = {The Vietnam Initiative for Zoonotic Infections (VIZIONS) includes community-based 'high-risk sentinel cohort' (HRSC) studies investigating individuals at risk of zoonotic infection due to occupational or residential exposure to animals. A total of 852 HRSC members were recruited between March 2013 and August 2014 from  three provinces (Ha Noi, Dak Lak, and Dong Thap). The most numerous group (72.8\%) corresponded to individuals living on farms, followed by slaughterers (16.3\%) and animal health workers (8.5\%). Nasal/pharyngeal and rectal swabs were collected from HRSC members at recruitment and after notifying illness. Exposure to exotic  animals (including wild pigs, porcupine, monkey, civet, bamboo rat and bat) was highest for the Dak Lak cohort (53.7\%), followed by Ha Noi (13.7\%) and Dong Thap  (4.0\%). A total of 26.8\% of individuals reported consumption of raw blood over the previous year; 33.6\% slaughterers reported no use of protective equipment at  work. Over 686 person-years of observation, 213 episodes of suspect infectious disease were notified, equivalent of 0.35 reports per person-year. Responsive samples were collected from animals in the farm cohort. There was noticeable time and space clustering of disease episodes suggesting that the VIZIONS set up is also suitable for the formal epidemiological investigation of disease outbreaks.},
	language = {eng},
	journal = {Scientific reports},
	author = {Carrique-Mas, Juan J. and Tue, Ngo T. and Bryant, Juliet E. and Saylors, Karen and Cuong, Nguyen V. and Hoa, Ngo T. and An, Nguyen N. and Hien, Vo B. and Lao, Pham V. and Tu, Nguyen C. and Chuyen, Nguyen K. and Chuc, Nguyen T. K. and Tan, Dinh V. and Duong, Hoang Van V. and Toan, Tran K. and Chi, Nguyen T. Y. and Campbell, James and Rabaa, Maia A. and Nadjm, Behzad and Woolhouse, Mark and Wertheim, Heiman and Thwaites, Guy and Baker, Stephen},
	month = dec,
	year = {2015},
	pmid = {26659094},
	pmcid = {PMC4674710},
	keywords = {*Sentinel Surveillance, Agriculture, Animals, Cluster Analysis, Cohort Studies, Communicable Diseases, Emerging/*epidemiology, Farmers, Geography, Medical, Humans, Meat Products/adverse effects, Occupational Exposure, Risk, Vietnam/epidemiology, Zoonoses/*epidemiology},
	pages = {17965},
}

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