@article{ceccaldi_added_2018-1,
	title = {Added value of {18F}-florbetaben amyloid {PET} in the diagnostic workup of most complex patients with dementia in {France}: {A} naturalistic study},
	volume = {14},
	issn = {1552-5279},
	shorttitle = {Added value of {18F}-florbetaben amyloid {PET} in the diagnostic workup of most complex patients with dementia in {France}},
	doi = {10.1016/j.jalz.2017.09.009},
	abstract = {INTRODUCTION: Although some studies have previously addressed the clinical impact of amyloid positron emission tomography (PET), none has specifically addressed its selective and hierarchical implementation in relation to cerebrospinal fluid analysis in a naturalistic setting.
METHODS: This multicenter study was performed at French tertiary memory clinics in patients presenting with most complex clinical situations (i.e., early-onset, atypical clinical profiles, suspected mixed etiological conditions, unexpected rate of progression), for whom cerebrospinal fluid analysis was indicated but either not feasible or considered as noncontributory (ClinicalTrials.gov: NCT02681172).
RESULTS: Two hundred five patients were enrolled with evaluable florbetaben PET scans; 64.4\% of scans were amyloid positive. PET results led to changed diagnosis and improved confidence in 66.8\% and 81.5\% of patients, respectively, and altered management in 80.0\% of cases.
DISCUSSION: High-level improvement of diagnostic certainty and management is provided by selective and hierarchical implementation of florbetaben PET into current standard practices for the most complex dementia cases.},
	language = {eng},
	number = {3},
	journal = {Alzheimer's \& Dementia: The Journal of the Alzheimer's Association},
	author = {Ceccaldi, Mathieu and Jonveaux, Thérèse and Verger, Antoine and Krolak-Salmon, Pierre and Houzard, Claire and Godefroy, Olivier and Shields, Trevor and Perrotin, Audrey and Gismondi, Rossella and Bullich, Santiago and Jovalekic, Aleksandar and Raffa, Nicola and Pasquier, Florence and Semah, Franck and Dubois, Bruno and Habert, Marie-Odile and Wallon, David and Chastan, Mathieu and Payoux, Pierre and {NEUUS in AD study group} and Stephens, Andrew and Guedj, Eric},
	month = mar,
	year = {2018},
	pmid = {29107051},
	keywords = {Aged, Humans, Dementia, Female, Male, Brain, Alzheimer's disease, France, Diagnosis, Differential, Positron-Emission Tomography, Radiopharmaceuticals, Amyloid, Amyloid imaging, Aniline Compounds, Clinical practice, Diagnosis, Florbetaben, Patient management, Stilbenes},
	pages = {293--305}
}

{"_id":"rjxKoBy2moSojEStr","bibbaseid":"ceccaldi-jonveaux-verger-krolaksalmon-houzard-godefroy-shields-perrotin-etal-addedvalueof18fflorbetabenamyloidpetinthediagnosticworkupofmostcomplexpatientswithdementiainfranceanaturalisticstudy-2018","authorIDs":[],"author_short":["Ceccaldi, M.","Jonveaux, T.","Verger, A.","Krolak-Salmon, P.","Houzard, C.","Godefroy, O.","Shields, T.","Perrotin, A.","Gismondi, R.","Bullich, S.","Jovalekic, A.","Raffa, N.","Pasquier, F.","Semah, F.","Dubois, B.","Habert, M.","Wallon, D.","Chastan, M.","Payoux, P.","NEUUS in AD study group","Stephens, A.","Guedj, E."],"bibdata":{"bibtype":"article","type":"article","title":"Added value of 18F-florbetaben amyloid PET in the diagnostic workup of most complex patients with dementia in France: A naturalistic study","volume":"14","issn":"1552-5279","shorttitle":"Added value of 18F-florbetaben amyloid PET in the diagnostic workup of most complex patients with dementia in France","doi":"10.1016/j.jalz.2017.09.009","abstract":"INTRODUCTION: Although some studies have previously addressed the clinical impact of amyloid positron emission tomography (PET), none has specifically addressed its selective and hierarchical implementation in relation to cerebrospinal fluid analysis in a naturalistic setting. METHODS: This multicenter study was performed at French tertiary memory clinics in patients presenting with most complex clinical situations (i.e., early-onset, atypical clinical profiles, suspected mixed etiological conditions, unexpected rate of progression), for whom cerebrospinal fluid analysis was indicated but either not feasible or considered as noncontributory (ClinicalTrials.gov: NCT02681172). RESULTS: Two hundred five patients were enrolled with evaluable florbetaben PET scans; 64.4% of scans were amyloid positive. PET results led to changed diagnosis and improved confidence in 66.8% and 81.5% of patients, respectively, and altered management in 80.0% of cases. DISCUSSION: High-level improvement of diagnostic certainty and management is provided by selective and hierarchical implementation of florbetaben PET into current standard practices for the most complex dementia cases.","language":"eng","number":"3","journal":"Alzheimer's & Dementia: The Journal of the Alzheimer's Association","author":[{"propositions":[],"lastnames":["Ceccaldi"],"firstnames":["Mathieu"],"suffixes":[]},{"propositions":[],"lastnames":["Jonveaux"],"firstnames":["Thérèse"],"suffixes":[]},{"propositions":[],"lastnames":["Verger"],"firstnames":["Antoine"],"suffixes":[]},{"propositions":[],"lastnames":["Krolak-Salmon"],"firstnames":["Pierre"],"suffixes":[]},{"propositions":[],"lastnames":["Houzard"],"firstnames":["Claire"],"suffixes":[]},{"propositions":[],"lastnames":["Godefroy"],"firstnames":["Olivier"],"suffixes":[]},{"propositions":[],"lastnames":["Shields"],"firstnames":["Trevor"],"suffixes":[]},{"propositions":[],"lastnames":["Perrotin"],"firstnames":["Audrey"],"suffixes":[]},{"propositions":[],"lastnames":["Gismondi"],"firstnames":["Rossella"],"suffixes":[]},{"propositions":[],"lastnames":["Bullich"],"firstnames":["Santiago"],"suffixes":[]},{"propositions":[],"lastnames":["Jovalekic"],"firstnames":["Aleksandar"],"suffixes":[]},{"propositions":[],"lastnames":["Raffa"],"firstnames":["Nicola"],"suffixes":[]},{"propositions":[],"lastnames":["Pasquier"],"firstnames":["Florence"],"suffixes":[]},{"propositions":[],"lastnames":["Semah"],"firstnames":["Franck"],"suffixes":[]},{"propositions":[],"lastnames":["Dubois"],"firstnames":["Bruno"],"suffixes":[]},{"propositions":[],"lastnames":["Habert"],"firstnames":["Marie-Odile"],"suffixes":[]},{"propositions":[],"lastnames":["Wallon"],"firstnames":["David"],"suffixes":[]},{"propositions":[],"lastnames":["Chastan"],"firstnames":["Mathieu"],"suffixes":[]},{"propositions":[],"lastnames":["Payoux"],"firstnames":["Pierre"],"suffixes":[]},{"firstnames":[],"propositions":[],"lastnames":["NEUUS in AD study group"],"suffixes":[]},{"propositions":[],"lastnames":["Stephens"],"firstnames":["Andrew"],"suffixes":[]},{"propositions":[],"lastnames":["Guedj"],"firstnames":["Eric"],"suffixes":[]}],"month":"March","year":"2018","pmid":"29107051","keywords":"Aged, Humans, Dementia, Female, Male, Brain, Alzheimer's disease, France, Diagnosis, Differential, Positron-Emission Tomography, Radiopharmaceuticals, Amyloid, Amyloid imaging, Aniline Compounds, Clinical practice, Diagnosis, Florbetaben, Patient management, Stilbenes","pages":"293–305","bibtex":"@article{ceccaldi_added_2018-1,\n\ttitle = {Added value of {18F}-florbetaben amyloid {PET} in the diagnostic workup of most complex patients with dementia in {France}: {A} naturalistic study},\n\tvolume = {14},\n\tissn = {1552-5279},\n\tshorttitle = {Added value of {18F}-florbetaben amyloid {PET} in the diagnostic workup of most complex patients with dementia in {France}},\n\tdoi = {10.1016/j.jalz.2017.09.009},\n\tabstract = {INTRODUCTION: Although some studies have previously addressed the clinical impact of amyloid positron emission tomography (PET), none has specifically addressed its selective and hierarchical implementation in relation to cerebrospinal fluid analysis in a naturalistic setting.\nMETHODS: This multicenter study was performed at French tertiary memory clinics in patients presenting with most complex clinical situations (i.e., early-onset, atypical clinical profiles, suspected mixed etiological conditions, unexpected rate of progression), for whom cerebrospinal fluid analysis was indicated but either not feasible or considered as noncontributory (ClinicalTrials.gov: NCT02681172).\nRESULTS: Two hundred five patients were enrolled with evaluable florbetaben PET scans; 64.4\\% of scans were amyloid positive. PET results led to changed diagnosis and improved confidence in 66.8\\% and 81.5\\% of patients, respectively, and altered management in 80.0\\% of cases.\nDISCUSSION: High-level improvement of diagnostic certainty and management is provided by selective and hierarchical implementation of florbetaben PET into current standard practices for the most complex dementia cases.},\n\tlanguage = {eng},\n\tnumber = {3},\n\tjournal = {Alzheimer's \\& Dementia: The Journal of the Alzheimer's Association},\n\tauthor = {Ceccaldi, Mathieu and Jonveaux, Thérèse and Verger, Antoine and Krolak-Salmon, Pierre and Houzard, Claire and Godefroy, Olivier and Shields, Trevor and Perrotin, Audrey and Gismondi, Rossella and Bullich, Santiago and Jovalekic, Aleksandar and Raffa, Nicola and Pasquier, Florence and Semah, Franck and Dubois, Bruno and Habert, Marie-Odile and Wallon, David and Chastan, Mathieu and Payoux, Pierre and {NEUUS in AD study group} and Stephens, Andrew and Guedj, Eric},\n\tmonth = mar,\n\tyear = {2018},\n\tpmid = {29107051},\n\tkeywords = {Aged, Humans, Dementia, Female, Male, Brain, Alzheimer's disease, France, Diagnosis, Differential, Positron-Emission Tomography, Radiopharmaceuticals, Amyloid, Amyloid imaging, Aniline Compounds, Clinical practice, Diagnosis, Florbetaben, Patient management, Stilbenes},\n\tpages = {293--305}\n}\n\n","author_short":["Ceccaldi, M.","Jonveaux, T.","Verger, A.","Krolak-Salmon, P.","Houzard, C.","Godefroy, O.","Shields, T.","Perrotin, A.","Gismondi, R.","Bullich, S.","Jovalekic, A.","Raffa, N.","Pasquier, F.","Semah, F.","Dubois, B.","Habert, M.","Wallon, D.","Chastan, M.","Payoux, P.","NEUUS in AD study group","Stephens, A.","Guedj, E."],"key":"ceccaldi_added_2018-1","id":"ceccaldi_added_2018-1","bibbaseid":"ceccaldi-jonveaux-verger-krolaksalmon-houzard-godefroy-shields-perrotin-etal-addedvalueof18fflorbetabenamyloidpetinthediagnosticworkupofmostcomplexpatientswithdementiainfranceanaturalisticstudy-2018","role":"author","urls":{},"keyword":["Aged","Humans","Dementia","Female","Male","Brain","Alzheimer's disease","France","Diagnosis","Differential","Positron-Emission Tomography","Radiopharmaceuticals","Amyloid","Amyloid imaging","Aniline Compounds","Clinical practice","Diagnosis","Florbetaben","Patient management","Stilbenes"],"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://github.com/leromela/bibtex/blob/main/Centre_Memoire.bib?raw=true","creationDate":"2021-02-10T14:03:34.459Z","downloads":0,"keywords":["aged","humans","dementia","female","male","brain","alzheimer's disease","france","diagnosis","differential","positron-emission tomography","radiopharmaceuticals","amyloid","amyloid imaging","aniline compounds","clinical practice","diagnosis","florbetaben","patient management","stilbenes"],"search_terms":["added","value","18f","florbetaben","amyloid","pet","diagnostic","workup","complex","patients","dementia","france","naturalistic","study","ceccaldi","jonveaux","verger","krolak-salmon","houzard","godefroy","shields","perrotin","gismondi","bullich","jovalekic","raffa","pasquier","semah","dubois","habert","wallon","chastan","payoux","neuus in ad study group","stephens","guedj"],"title":"Added value of 18F-florbetaben amyloid PET in the diagnostic workup of most complex patients with dementia in France: A naturalistic study","year":2018,"dataSources":["j489FYr48Mag45aCq"]}