Luminescent quantum dots for multiplexed biological detection and imaging. Chan, W. C. W, Maxwell, D. J, Gao, X., Bailey, R. E, Han, M., & Nie, S. Current Opinion in Biotechnology, 13(1):40–46, February, 2002. ![Luminescent quantum dots for multiplexed biological detection and imaging [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex Recent advances in nanomaterials have produced a new class of fluorescent labels by conjugating semiconductor quantum dots with biorecognition molecules. These nanometer-sized conjugates are water-soluble and biocompatible, and provide important advantages over organic dyes and lanthanide probes. In particular, the emission wavelength of quantum-dot nanocrystals can be continuously tuned by changing the particle size, and a single light source can be used for simultaneous excitation of all different-sized dots. High-quality dots are also highly stable against photobleaching and have narrow, symmetric emission spectra. These novel optical properties render quantum dots ideal fluorophores for ultrasensitive, multicolor, and multiplexing applications in molecular biotechnology and bioengineering.
@article{chan_luminescent_2002,
title = {Luminescent quantum dots for multiplexed biological detection and imaging},
volume = {13},
issn = {0958-1669},
url = {https://www.sciencedirect.com/science/article/pii/S0958166902002823},
doi = {10.1016/S0958-1669(02)00282-3},
abstract = {Recent advances in nanomaterials have produced a new class of fluorescent labels by conjugating semiconductor quantum dots with biorecognition molecules. These nanometer-sized conjugates are water-soluble and biocompatible, and provide important advantages over organic dyes and lanthanide probes. In particular, the emission wavelength of quantum-dot nanocrystals can be continuously tuned by changing the particle size, and a single light source can be used for simultaneous excitation of all different-sized dots. High-quality dots are also highly stable against photobleaching and have narrow, symmetric emission spectra. These novel optical properties render quantum dots ideal fluorophores for ultrasensitive, multicolor, and multiplexing applications in molecular biotechnology and bioengineering.},
language = {en},
number = {1},
urldate = {2021-11-06},
journal = {Current Opinion in Biotechnology},
author = {Chan, Warren C. W and Maxwell, Dustin J and Gao, Xiaohu and Bailey, Robert E and Han, Mingyong and Nie, Shuming},
month = feb,
year = {2002},
keywords = {cells, fluorescence, genes, multiplexing, optical encoding, proteins, quantum dots, ultrasensitive},
pages = {40--46},
file = {ScienceDirect Full Text PDF:files/2289/Chan et al. - 2002 - Luminescent quantum dots for multiplexed biologica.pdf:application/pdf;ScienceDirect Snapshot:files/2290/S0958166902002823.html:text/html},
}
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