Artifacts in T1??-weighted imaging: Correction with a self-compensating spin-locking pulse. Charagundla, S. R., Borthakur, A., Leigh, J. S., & Reddy, R. Journal of Magnetic Resonance, 162(1):113--121, 2003.
doi  abstract   bibtex   
Significant artifacts arise in T1??-weighted imaging when nutation angles suffer small deviations from their expected values. These artifacts vary with spin-locking time and amplitude, severely limiting attempts to perform quantitative imaging or measurement of T1?? relaxation times. A theoretical model explaining the origin of these artifacts is presented in the context of a T1??-prepared fast spin-echo imaging sequence. Experimentally obtained artifacts are compared to those predicted by theory and related to B1 inhomogeneity. Finally, a "self-compensating" spin-locking preparatory pulse cluster is presented, in which the second half of the spin-locking pulse is phase-shifted by 180??. Use of this pulse sequence maintains relatively uniform signal intensity despite large variations in flip angle, greatly reducing artifacts in T1??-weighted imaging. ?? 2003 Elsevier Science (USA). All rights reserved.
@article{ Charagundla2003,
  abstract = {Significant artifacts arise in T1??-weighted imaging when nutation angles suffer small deviations from their expected values. These artifacts vary with spin-locking time and amplitude, severely limiting attempts to perform quantitative imaging or measurement of T1?? relaxation times. A theoretical model explaining the origin of these artifacts is presented in the context of a T1??-prepared fast spin-echo imaging sequence. Experimentally obtained artifacts are compared to those predicted by theory and related to B1 inhomogeneity. Finally, a "self-compensating" spin-locking preparatory pulse cluster is presented, in which the second half of the spin-locking pulse is phase-shifted by 180??. Use of this pulse sequence maintains relatively uniform signal intensity despite large variations in flip angle, greatly reducing artifacts in T1??-weighted imaging. ?? 2003 Elsevier Science (USA). All rights reserved.},
  author = {Charagundla, Sridhar R. and Borthakur, Arijitt and Leigh, John S. and Reddy, Ravinder},
  doi = {10.1016/S1090-7807(02)00197-0},
  file = {:home/jk636/c/public_html/shared/papers/T1rho Background_Science/Charagundla_JMR_2002.pdf:pdf},
  isbn = {1090-7807 (Print)$\backslash$n1090-7807 (Linking)},
  issn = {10907807},
  journal = {Journal of Magnetic Resonance},
  keywords = {Artifacts,B1,MRI,Rotary echo,T1??},
  number = {1},
  pages = {113--121},
  pmid = {12762988},
  title = {{Artifacts in T1??-weighted imaging: Correction with a self-compensating spin-locking pulse}},
  volume = {162},
  year = {2003}
}

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