The history of injectable silicone fluids for soft-tissue augmentation. Chasan, P. E Plastic and reconstructive surgery, 120(7):2034–2040, December, 2007. Place: United States Publisher: Lippincott Williams & Wilkins![The history of injectable silicone fluids for soft-tissue augmentation. [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex Background: The debate over the legitimacy of silicone as a safe tool for soft-tissue augmentation has spanned well over half a century. Proponents concede that injections of questionable purity and/or of massive quantities have produced unfavorable outcomes. They assert that in experienced hands with "injectable-grade" silicone, there are very few problems. Despite these claims, the literature is replete with disastrous outcomes following silicone fluid injection, often many years after the initial treatment.; Methods: An extensive review of the English-language literature was conducted using MEDLINE.; Results: A comprehensive review of injectable silicones was completed, revealing the origins, misuses, early clinical trials, and support for and against the injection of silicone fluids for the augmentation of soft tissues.; Conclusions: A better understanding of the history of injectable silicone fluids for soft-tissue augmentation can give insight into the pitfalls and complications surrounding its use. There has been an evolution in the technique and type of products used for soft-tissue augmentation. In its current use, silicone oil for permanent soft-tissue augmentation could be a very powerful tool. There is some literature that supports the use of a small amount of purified, high-viscosity silicone oil; however, there has not been a single longitudinal study to date with appropriate follow-up data. The unanswered question remains: Are the risks worth the potential benefits of silicone oil as a permanent filler?
@article{chasan_history_2007,
title = {The history of injectable silicone fluids for soft-tissue augmentation.},
volume = {120},
issn = {1529-4242},
url = {https://search.ebscohost.com/login.aspx?direct=true&db=mnh&AN=18090770&site=ehost-live&scope=site},
doi = {10.1097/01.prs.0000267580.92163.33},
abstract = {Background: The debate over the legitimacy of silicone as a safe tool for soft-tissue augmentation has spanned well over half a century. Proponents concede that injections of questionable purity and/or of massive quantities have produced unfavorable outcomes. They assert that in experienced hands with "injectable-grade" silicone, there are very few problems. Despite these claims, the literature is replete with disastrous outcomes following silicone fluid injection, often many years after the initial treatment.; Methods: An extensive review of the English-language literature was conducted using MEDLINE.; Results: A comprehensive review of injectable silicones was completed, revealing the origins, misuses, early clinical trials, and support for and against the injection of silicone fluids for the augmentation of soft tissues.; Conclusions: A better understanding of the history of injectable silicone fluids for soft-tissue augmentation can give insight into the pitfalls and complications surrounding its use. There has been an evolution in the technique and type of products used for soft-tissue augmentation. In its current use, silicone oil for permanent soft-tissue augmentation could be a very powerful tool. There is some literature that supports the use of a small amount of purified, high-viscosity silicone oil; however, there has not been a single longitudinal study to date with appropriate follow-up data. The unanswered question remains: Are the risks worth the potential benefits of silicone oil as a permanent filler?},
number = {7},
journal = {Plastic and reconstructive surgery},
author = {Chasan, Paul E},
month = dec,
year = {2007},
note = {Place: United States
Publisher: Lippincott Williams \& Wilkins},
keywords = {Animals, Breast, Cosmetic Techniques/*adverse effects, Dimethylpolysiloxanes/*adverse effects, Dimethylpolysiloxanes/administration \& dosage, Drug Contamination, Drug Evaluation, Preclinical, Face, Facial Hemiatrophy/therapy, Granuloma, Foreign-Body/*chemically induced, Humans, Injections, Lipodystrophy/therapy, Silicone Oils/*adverse effects, Silicone Oils/administration \& dosage, Silicones/administration \& dosage, Silicones/chemistry, Time Factors, Viscosity},
pages = {2034--2040},
}
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Despite these claims, the literature is replete with disastrous outcomes following silicone fluid injection, often many years after the initial treatment.; Methods: An extensive review of the English-language literature was conducted using MEDLINE.; Results: A comprehensive review of injectable silicones was completed, revealing the origins, misuses, early clinical trials, and support for and against the injection of silicone fluids for the augmentation of soft tissues.; Conclusions: A better understanding of the history of injectable silicone fluids for soft-tissue augmentation can give insight into the pitfalls and complications surrounding its use. There has been an evolution in the technique and type of products used for soft-tissue augmentation. In its current use, silicone oil for permanent soft-tissue augmentation could be a very powerful tool. There is some literature that supports the use of a small amount of purified, high-viscosity silicone oil; however, there has not been a single longitudinal study to date with appropriate follow-up data. The unanswered question remains: Are the risks worth the potential benefits of silicone oil as a permanent filler?","number":"7","journal":"Plastic and reconstructive surgery","author":[{"propositions":[],"lastnames":["Chasan"],"firstnames":["Paul","E"],"suffixes":[]}],"month":"December","year":"2007","note":"Place: United States Publisher: Lippincott Williams & Wilkins","keywords":"Animals, Breast, Cosmetic Techniques/*adverse effects, Dimethylpolysiloxanes/*adverse effects, Dimethylpolysiloxanes/administration & dosage, Drug Contamination, Drug Evaluation, Preclinical, Face, Facial Hemiatrophy/therapy, Granuloma, Foreign-Body/*chemically induced, Humans, Injections, Lipodystrophy/therapy, Silicone Oils/*adverse effects, Silicone Oils/administration & dosage, Silicones/administration & dosage, Silicones/chemistry, Time Factors, Viscosity","pages":"2034–2040","bibtex":"@article{chasan_history_2007,\n\ttitle = {The history of injectable silicone fluids for soft-tissue augmentation.},\n\tvolume = {120},\n\tissn = {1529-4242},\n\turl = {https://search.ebscohost.com/login.aspx?direct=true&db=mnh&AN=18090770&site=ehost-live&scope=site},\n\tdoi = {10.1097/01.prs.0000267580.92163.33},\n\tabstract = {Background: The debate over the legitimacy of silicone as a safe tool for soft-tissue augmentation has spanned well over half a century. Proponents concede that injections of questionable purity and/or of massive quantities have produced unfavorable outcomes. They assert that in experienced hands with \"injectable-grade\" silicone, there are very few problems. Despite these claims, the literature is replete with disastrous outcomes following silicone fluid injection, often many years after the initial treatment.; Methods: An extensive review of the English-language literature was conducted using MEDLINE.; Results: A comprehensive review of injectable silicones was completed, revealing the origins, misuses, early clinical trials, and support for and against the injection of silicone fluids for the augmentation of soft tissues.; Conclusions: A better understanding of the history of injectable silicone fluids for soft-tissue augmentation can give insight into the pitfalls and complications surrounding its use. There has been an evolution in the technique and type of products used for soft-tissue augmentation. In its current use, silicone oil for permanent soft-tissue augmentation could be a very powerful tool. There is some literature that supports the use of a small amount of purified, high-viscosity silicone oil; however, there has not been a single longitudinal study to date with appropriate follow-up data. The unanswered question remains: Are the risks worth the potential benefits of silicone oil as a permanent filler?},\n\tnumber = {7},\n\tjournal = {Plastic and reconstructive surgery},\n\tauthor = {Chasan, Paul E},\n\tmonth = dec,\n\tyear = {2007},\n\tnote = {Place: United States\nPublisher: Lippincott Williams \\& Wilkins},\n\tkeywords = {Animals, Breast, Cosmetic Techniques/*adverse effects, Dimethylpolysiloxanes/*adverse effects, Dimethylpolysiloxanes/administration \\& dosage, Drug Contamination, Drug Evaluation, Preclinical, Face, Facial Hemiatrophy/therapy, Granuloma, Foreign-Body/*chemically induced, Humans, Injections, Lipodystrophy/therapy, Silicone Oils/*adverse effects, Silicone Oils/administration \\& dosage, Silicones/administration \\& dosage, Silicones/chemistry, Time Factors, Viscosity},\n\tpages = {2034--2040},\n}\n\n\n\n","author_short":["Chasan, P. 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