@article{chen_development_2021,
	title = {The development of ru({Ii})-based photoactivated chemotherapy agents},
	volume = {26},
	issn = {14203049},
	doi = {10.3390/molecules26185679},
	abstract = {Photoactivated chemotherapy (PACT) is a novel cancer treatment method that has drawn increasing attention due to its high selectivity and low side effects by spatio-temporal control of irradiation. Compared with photodynamic therapy (PDT), oxygen-independent PACT is more suit-able for treating hypoxic tumors. By finely tuning ligand structures and coordination configurations, many Ru(II) complexes can undergo photoinduced ligand dissociation, and the resulting Ru(II) aqua species and/or free ligands may have anticancer activity, showing their potential as PACT agents. In this mini-review, we summarized the progress in Ru(II)-based PACT agents, as well as challenges that researchers in this field still face.},
	number = {18},
	journal = {Molecules},
	author = {Chen, Yongjie and Bai, Lijuan and Zhang, Pu and Zhao, Hua and Zhou, Qianxiong},
	year = {2021},
	pmid = {34577150},
	keywords = {Photoinduced ligand dissociation, Ru(II) complexes, photoactivated chemotherapy (PACT)},
	pages = {1--20},
}

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