@article{chen_genetic_2022,
	title = {Genetic architecture behind developmental and seasonal control of tree growth and wood properties in {Norway} spruce},
	volume = {13},
	issn = {1664-462X},
	url = {https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2022.927673/full},
	doi = {10.3389/fpls.2022.927673},
	abstract = {Genetic control of tree growth and wood formation varies depending on the age of the tree and the time of the year. Single-locus, multi-locus, and multitrait genome-wide association studies (GWAS) were conducted on 34 growth and wood property traits in 1303 Norway spruce individuals using exome capture to cover {\textasciitilde}130K single nucleotide polymorphisms (SNPs). GWAS identified associations to the different wood traits in a total of 85 gene models, and several of these were validated in a population of the mother trees. A multi-locus GWAS model identified more SNPs associated with the studied traits than single-locus or multivariate models. Changes in tree age and annual season influenced the genetic architecture of growth and wood properties in unique ways, manifested by non-overlapping SNP loci. In addition to completely novel candidate genes, SNPs were located in genes previously associated with wood formation, such as cellulose synthases and a NAC transcription factor, but that have not been earlier linked to seasonal or age-dependent regulation of wood properties. Interestingly, SNPs associated with the width of the year rings were identified in homologs of Arabidopsis thaliana BARELY ANY MERISTEM 1 and rice BIG GRAIN 1 which have been previously shown to control cell division and biomass production. The results provide tools for future Norway spruce breeding and functional studies.},
	language = {English},
	urldate = {2026-04-10},
	journal = {Frontiers in Plant Science},
	publisher = {Frontiers},
	author = {Chen, Zhi-Qiang and Zan, Yanjun and Zhou, Linghua and Karlsson, Bo and Tuominen, Hannele and García-Gil, Maria Rosario and Wu, Harry X.},
	month = aug,
	year = {2022},
	keywords = {Developmental Stage, Norway spruce, Seasonal variation, Wood properties, genome-wide association, ⛔ No DOI found},
}

{"_id":"ZcsKEpp7A2wwNdCaK","bibbaseid":"chen-zan-zhou-karlsson-tuominen-garcagil-wu-geneticarchitecturebehinddevelopmentalandseasonalcontroloftreegrowthandwoodpropertiesinnorwayspruce-2022","author_short":["Chen, Z.","Zan, Y.","Zhou, L.","Karlsson, B.","Tuominen, H.","García-Gil, M. R.","Wu, H. X."],"bibdata":{"bibtype":"article","type":"article","title":"Genetic architecture behind developmental and seasonal control of tree growth and wood properties in Norway spruce","volume":"13","issn":"1664-462X","url":"https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2022.927673/full","doi":"10.3389/fpls.2022.927673","abstract":"Genetic control of tree growth and wood formation varies depending on the age of the tree and the time of the year. Single-locus, multi-locus, and multitrait genome-wide association studies (GWAS) were conducted on 34 growth and wood property traits in 1303 Norway spruce individuals using exome capture to cover ~130K single nucleotide polymorphisms (SNPs). GWAS identified associations to the different wood traits in a total of 85 gene models, and several of these were validated in a population of the mother trees. A multi-locus GWAS model identified more SNPs associated with the studied traits than single-locus or multivariate models. Changes in tree age and annual season influenced the genetic architecture of growth and wood properties in unique ways, manifested by non-overlapping SNP loci. In addition to completely novel candidate genes, SNPs were located in genes previously associated with wood formation, such as cellulose synthases and a NAC transcription factor, but that have not been earlier linked to seasonal or age-dependent regulation of wood properties. Interestingly, SNPs associated with the width of the year rings were identified in homologs of Arabidopsis thaliana BARELY ANY MERISTEM 1 and rice BIG GRAIN 1 which have been previously shown to control cell division and biomass production. The results provide tools for future Norway spruce breeding and functional studies.","language":"English","urldate":"2026-04-10","journal":"Frontiers in Plant Science","publisher":"Frontiers","author":[{"propositions":[],"lastnames":["Chen"],"firstnames":["Zhi-Qiang"],"suffixes":[]},{"propositions":[],"lastnames":["Zan"],"firstnames":["Yanjun"],"suffixes":[]},{"propositions":[],"lastnames":["Zhou"],"firstnames":["Linghua"],"suffixes":[]},{"propositions":[],"lastnames":["Karlsson"],"firstnames":["Bo"],"suffixes":[]},{"propositions":[],"lastnames":["Tuominen"],"firstnames":["Hannele"],"suffixes":[]},{"propositions":[],"lastnames":["García-Gil"],"firstnames":["Maria","Rosario"],"suffixes":[]},{"propositions":[],"lastnames":["Wu"],"firstnames":["Harry","X."],"suffixes":[]}],"month":"August","year":"2022","keywords":"Developmental Stage, Norway spruce, Seasonal variation, Wood properties, genome-wide association, ⛔ No DOI found","bibtex":"@article{chen_genetic_2022,\n\ttitle = {Genetic architecture behind developmental and seasonal control of tree growth and wood properties in {Norway} spruce},\n\tvolume = {13},\n\tissn = {1664-462X},\n\turl = {https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2022.927673/full},\n\tdoi = {10.3389/fpls.2022.927673},\n\tabstract = {Genetic control of tree growth and wood formation varies depending on the age of the tree and the time of the year. Single-locus, multi-locus, and multitrait genome-wide association studies (GWAS) were conducted on 34 growth and wood property traits in 1303 Norway spruce individuals using exome capture to cover {\\textasciitilde}130K single nucleotide polymorphisms (SNPs). GWAS identified associations to the different wood traits in a total of 85 gene models, and several of these were validated in a population of the mother trees. A multi-locus GWAS model identified more SNPs associated with the studied traits than single-locus or multivariate models. Changes in tree age and annual season influenced the genetic architecture of growth and wood properties in unique ways, manifested by non-overlapping SNP loci. In addition to completely novel candidate genes, SNPs were located in genes previously associated with wood formation, such as cellulose synthases and a NAC transcription factor, but that have not been earlier linked to seasonal or age-dependent regulation of wood properties. Interestingly, SNPs associated with the width of the year rings were identified in homologs of Arabidopsis thaliana BARELY ANY MERISTEM 1 and rice BIG GRAIN 1 which have been previously shown to control cell division and biomass production. The results provide tools for future Norway spruce breeding and functional studies.},\n\tlanguage = {English},\n\turldate = {2026-04-10},\n\tjournal = {Frontiers in Plant Science},\n\tpublisher = {Frontiers},\n\tauthor = {Chen, Zhi-Qiang and Zan, Yanjun and Zhou, Linghua and Karlsson, Bo and Tuominen, Hannele and García-Gil, Maria Rosario and Wu, Harry X.},\n\tmonth = aug,\n\tyear = {2022},\n\tkeywords = {Developmental Stage, Norway spruce, Seasonal variation, Wood properties, genome-wide association, ⛔ No DOI found},\n}\n\n\n\n\n\n\n\n","author_short":["Chen, Z.","Zan, Y.","Zhou, L.","Karlsson, B.","Tuominen, H.","García-Gil, M. R.","Wu, H. 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