Determining the Size and Shape Dependence of Gold Nanoparticle Uptake into Mammalian Cells. Chithrani, B. D., Ghazani, A. A., & Chan, W. C. W. Nano Lett., 6(4):662–668, April, 2006. Publisher: American Chemical Society![Determining the Size and Shape Dependence of Gold Nanoparticle Uptake into Mammalian Cells [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex We investigated the intracellular uptake of different sized and shaped colloidal gold nanoparticles. We showed that kinetics and saturation concentrations are highly dependent upon the physical dimensions of the nanoparticles (e.g., uptake half-life of 14, 50, and 74 nm nanoparticles is 2.10, 1.90, and 2.24 h, respectively). The findings from this study will have implications in the chemical design of nanostructures for biomedical applications (e.g., tuning intracellular delivery rates and amounts by nanoscale dimensions and engineering complex, multifunctional nanostructures for imaging and therapeutics).
@article{chithrani_determining_2006,
title = {Determining the {Size} and {Shape} {Dependence} of {Gold} {Nanoparticle} {Uptake} into {Mammalian} {Cells}},
volume = {6},
issn = {1530-6984},
url = {https://doi.org/10.1021/nl052396o},
doi = {10.1021/nl052396o},
abstract = {We investigated the intracellular uptake of different sized and shaped colloidal gold nanoparticles. We showed that kinetics and saturation concentrations are highly dependent upon the physical dimensions of the nanoparticles (e.g., uptake half-life of 14, 50, and 74 nm nanoparticles is 2.10, 1.90, and 2.24 h, respectively). The findings from this study will have implications in the chemical design of nanostructures for biomedical applications (e.g., tuning intracellular delivery rates and amounts by nanoscale dimensions and engineering complex, multifunctional nanostructures for imaging and therapeutics).},
number = {4},
urldate = {2021-11-06},
journal = {Nano Lett.},
author = {Chithrani, B. Devika and Ghazani, Arezou A. and Chan, Warren C. W.},
month = apr,
year = {2006},
note = {Publisher: American Chemical Society},
pages = {662--668},
file = {Full Text PDF:files/2251/Chithrani et al. - 2006 - Determining the Size and Shape Dependence of Gold .pdf:application/pdf;ACS Full Text Snapshot:files/2255/nl052396o.html:text/html},
}
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