Varicella screening and vaccination for healthcare workers at KK Women's and Children's Hospital. Chong, C. Y., Lim, S. H., Ng, W. Y. M., Tee, N., & Lin, R. V. T. P. Annals of the Academy of Medicine, Singapore, 33(2):243–7, 2004. Paper abstract bibtex INTRODUCTION: Varicella is a highly contagious disease with significant morbidity and mortality, especially in adults. It can lead to nosocomial transmission with dire consequences, especially in a healthcare facility where children and pregnant women form the majority of patients. At KK Women's and Children's Hospital, we embarked on a programme in 2 phases, between 1997 and 1999, to screen healthcare workers (HCWs) for varicella immunity and to offer varicella vaccination to those who tested negative for antibody., MATERIALS AND METHODS: HCWs were initially screened via a questionnaire; those with no previous history of chickenpox underwent a blood test for varicella zoster antibody. Varicella vaccine was offered to those who tested negative for antibody and they were monitored for adverse reactions., RESULTS: Of the HCWs surveyed, 14.7% and 26.9% in phases 1 and 2, respectively, had no previous history of chickenpox. Of these, 55.3% in phase 1 and 26.1% in phase 2 tested negative for antibodies. Thus, the overall seronegativity of all HCWs surveyed was between 6.5% and 7.6%. Among those who tested negative for antibodies, 42.9% in phase 1 and 74% in phase 2 were vaccinated. Hence, the overall vaccination rate in HCWs was 3.2% and 4.8% in phases 1 and 2, respectively. Adverse reactions were observed in 2 (22.2%) HCWs in phase 1 and in 9 (9.3%) in phase 2, consisting mostly of maculopapular rashes or vesicles around the injection site., CONCLUSIONS: Our study shows that 26% to 55% of HCWs with no history of chickenpox and who tested negative for antibody against varicella required vaccination. Hence, in healthcare facilities, varicella screening and vaccination should be offered to all HCWs.
@article{chong_varicella_2004,
title = {Varicella screening and vaccination for healthcare workers at {KK} {Women}'s and {Children}'s {Hospital}},
volume = {33},
issn = {0304-4602},
url = {http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=med5&NEWS=N&AN=15098642},
abstract = {INTRODUCTION: Varicella is a highly contagious disease with significant morbidity and mortality, especially in adults. It can lead to nosocomial transmission with dire consequences, especially in a healthcare facility where children and pregnant women form the majority of patients. At KK Women's and Children's Hospital, we embarked on a programme in 2 phases, between 1997 and 1999, to screen healthcare workers (HCWs) for varicella immunity and to offer varicella vaccination to those who tested negative for antibody., MATERIALS AND METHODS: HCWs were initially screened via a questionnaire; those with no previous history of chickenpox underwent a blood test for varicella zoster antibody. Varicella vaccine was offered to those who tested negative for antibody and they were monitored for adverse reactions., RESULTS: Of the HCWs surveyed, 14.7\% and 26.9\% in phases 1 and 2, respectively, had no previous history of chickenpox. Of these, 55.3\% in phase 1 and 26.1\% in phase 2 tested negative for antibodies. Thus, the overall seronegativity of all HCWs surveyed was between 6.5\% and 7.6\%. Among those who tested negative for antibodies, 42.9\% in phase 1 and 74\% in phase 2 were vaccinated. Hence, the overall vaccination rate in HCWs was 3.2\% and 4.8\% in phases 1 and 2, respectively. Adverse reactions were observed in 2 (22.2\%) HCWs in phase 1 and in 9 (9.3\%) in phase 2, consisting mostly of maculopapular rashes or vesicles around the injection site., CONCLUSIONS: Our study shows that 26\% to 55\% of HCWs with no history of chickenpox and who tested negative for antibody against varicella required vaccination. Hence, in healthcare facilities, varicella screening and vaccination should be offered to all HCWs.},
number = {2},
journal = {Annals of the Academy of Medicine, Singapore},
author = {Chong, C. Y. and Lim, S. H. and Ng, W. Y. M. and Tee, N. and Lin, R. V. T. P.},
year = {2004},
keywords = {*Health Personnel, *Herpes Zoster/di [Diagnosis], *Herpes Zoster/pc [Prevention \& Control], *Occupational Diseases/di [Diagnosis], *Occupational Diseases/pc [Prevention \& Control], *Vaccination, Adult, Antibodies, Viral/bl [Blood], Chickenpox Vaccine, Health Surveys, Herpes Zoster/im [Immunology], Herpesvirus 3, Human/im [Immunology], Hospitals, Pediatric, Humans, Occupational Diseases/im [Immunology], Program Evaluation, Singapore, Women's Health Services},
pages = {243--7},
}
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At KK Women's and Children's Hospital, we embarked on a programme in 2 phases, between 1997 and 1999, to screen healthcare workers (HCWs) for varicella immunity and to offer varicella vaccination to those who tested negative for antibody., MATERIALS AND METHODS: HCWs were initially screened via a questionnaire; those with no previous history of chickenpox underwent a blood test for varicella zoster antibody. Varicella vaccine was offered to those who tested negative for antibody and they were monitored for adverse reactions., RESULTS: Of the HCWs surveyed, 14.7% and 26.9% in phases 1 and 2, respectively, had no previous history of chickenpox. Of these, 55.3% in phase 1 and 26.1% in phase 2 tested negative for antibodies. Thus, the overall seronegativity of all HCWs surveyed was between 6.5% and 7.6%. Among those who tested negative for antibodies, 42.9% in phase 1 and 74% in phase 2 were vaccinated. Hence, the overall vaccination rate in HCWs was 3.2% and 4.8% in phases 1 and 2, respectively. Adverse reactions were observed in 2 (22.2%) HCWs in phase 1 and in 9 (9.3%) in phase 2, consisting mostly of maculopapular rashes or vesicles around the injection site., CONCLUSIONS: Our study shows that 26% to 55% of HCWs with no history of chickenpox and who tested negative for antibody against varicella required vaccination. Hence, in healthcare facilities, varicella screening and vaccination should be offered to all HCWs.","number":"2","journal":"Annals of the Academy of Medicine, Singapore","author":[{"propositions":[],"lastnames":["Chong"],"firstnames":["C.","Y."],"suffixes":[]},{"propositions":[],"lastnames":["Lim"],"firstnames":["S.","H."],"suffixes":[]},{"propositions":[],"lastnames":["Ng"],"firstnames":["W.","Y.","M."],"suffixes":[]},{"propositions":[],"lastnames":["Tee"],"firstnames":["N."],"suffixes":[]},{"propositions":[],"lastnames":["Lin"],"firstnames":["R.","V.","T.","P."],"suffixes":[]}],"year":"2004","keywords":"*Health Personnel, *Herpes Zoster/di [Diagnosis], *Herpes Zoster/pc [Prevention & Control], *Occupational Diseases/di [Diagnosis], *Occupational Diseases/pc [Prevention & Control], *Vaccination, Adult, Antibodies, Viral/bl [Blood], Chickenpox Vaccine, Health Surveys, Herpes Zoster/im [Immunology], Herpesvirus 3, Human/im [Immunology], Hospitals, Pediatric, Humans, Occupational Diseases/im [Immunology], Program Evaluation, Singapore, Women's Health Services","pages":"243–7","bibtex":"@article{chong_varicella_2004,\n\ttitle = {Varicella screening and vaccination for healthcare workers at {KK} {Women}'s and {Children}'s {Hospital}},\n\tvolume = {33},\n\tissn = {0304-4602},\n\turl = {http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=med5&NEWS=N&AN=15098642},\n\tabstract = {INTRODUCTION: Varicella is a highly contagious disease with significant morbidity and mortality, especially in adults. It can lead to nosocomial transmission with dire consequences, especially in a healthcare facility where children and pregnant women form the majority of patients. At KK Women's and Children's Hospital, we embarked on a programme in 2 phases, between 1997 and 1999, to screen healthcare workers (HCWs) for varicella immunity and to offer varicella vaccination to those who tested negative for antibody., MATERIALS AND METHODS: HCWs were initially screened via a questionnaire; those with no previous history of chickenpox underwent a blood test for varicella zoster antibody. Varicella vaccine was offered to those who tested negative for antibody and they were monitored for adverse reactions., RESULTS: Of the HCWs surveyed, 14.7\\% and 26.9\\% in phases 1 and 2, respectively, had no previous history of chickenpox. Of these, 55.3\\% in phase 1 and 26.1\\% in phase 2 tested negative for antibodies. Thus, the overall seronegativity of all HCWs surveyed was between 6.5\\% and 7.6\\%. Among those who tested negative for antibodies, 42.9\\% in phase 1 and 74\\% in phase 2 were vaccinated. Hence, the overall vaccination rate in HCWs was 3.2\\% and 4.8\\% in phases 1 and 2, respectively. Adverse reactions were observed in 2 (22.2\\%) HCWs in phase 1 and in 9 (9.3\\%) in phase 2, consisting mostly of maculopapular rashes or vesicles around the injection site., CONCLUSIONS: Our study shows that 26\\% to 55\\% of HCWs with no history of chickenpox and who tested negative for antibody against varicella required vaccination. Hence, in healthcare facilities, varicella screening and vaccination should be offered to all HCWs.},\n\tnumber = {2},\n\tjournal = {Annals of the Academy of Medicine, Singapore},\n\tauthor = {Chong, C. Y. and Lim, S. H. and Ng, W. Y. M. and Tee, N. and Lin, R. V. T. 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