Middle east respiratory syndrome (MERS) and influenza surveillance for returned travellers from MERS-affected areas. Chow, A., Ho, H., & Win, M. K. Annals of the Academy of Medicine Singapore, 45(9 Supplement 1):S211, 2016. Paper abstract bibtex Background & Hypothesis: Since the emergence of the Middle East respiratory syndrome (MERS) coronavirus (CoV) in 2012, an active surveillance programme for travellers returning from MERS-affected areas has been implemented in our hospital. Method(s): We conducted an analytic cross-sectional study of suspected MERS patients admitted to our hospital from 25 September 2012 through 10 February 2016, to compare the clinical epidemiology in Singapore residents with non-residents. We compared differences in epidemiological and clinical characteristics, using t-test for continuous variables and chi-square test for categorical variables. We then constructed multivariable logistic regression models to assess for independent factors associated with influenza infection in the returned travellers. Result(s): MERS Co-V was not detected in the 262 patients investigated. Half were male and almost two-thirds (65.3%) were Singapore residents. Residents (mean 54.1 [SD 14.9] years) and non-residents (mean 56.8 [SD 16.1]) were similar in age (P = 0.171). Majority (60.7%) had returned from the Kingdom of Saudi Arabia, with significantly more Singapore residents (69.6%) than non-residents (44.0%) returning from the Kingdom (P \textless0.001). Cough (91.6%) and fever (90.5%) were the most common presenting symptoms. A significantly higher proportion of non-residents (45.1%) than residents (22.2%) were being infected with influenza (P \textless0.001). After adjusting for age, travel destination, and admission month, non-residents were thrice as likely as residents to have an influenza infection (OR: 2.96; 95% CI, 1.61-5.44; P \textless0.001). Discussion & Conclusion(s): Influenza was common among returned travellers from MERS-affected areas, especially in nonresidents. Influenza vaccination and good personal hygiene should be actively promoted to all travellers to MERS-affected areas.
@article{chow_middle_2016,
title = {Middle east respiratory syndrome ({MERS}) and influenza surveillance for returned travellers from {MERS}-affected areas},
volume = {45},
issn = {0304-4602},
url = {http://www.annals.edu.sg/pdf/45VolNo9Sep2016/SHBC2016.pdf http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=emed17&NEWS=N&AN=612898057},
abstract = {Background \& Hypothesis: Since the emergence of the Middle East respiratory syndrome (MERS) coronavirus (CoV) in 2012, an active surveillance programme for travellers returning from MERS-affected areas has been implemented in our hospital. Method(s): We conducted an analytic cross-sectional study of suspected MERS patients admitted to our hospital from 25 September 2012 through 10 February 2016, to compare the clinical epidemiology in Singapore residents with non-residents. We compared differences in epidemiological and clinical characteristics, using t-test for continuous variables and chi-square test for categorical variables. We then constructed multivariable logistic regression models to assess for independent factors associated with influenza infection in the returned travellers. Result(s): MERS Co-V was not detected in the 262 patients investigated. Half were male and almost two-thirds (65.3\%) were Singapore residents. Residents (mean 54.1 [SD 14.9] years) and non-residents (mean 56.8 [SD 16.1]) were similar in age (P = 0.171). Majority (60.7\%) had returned from the Kingdom of Saudi Arabia, with significantly more Singapore residents (69.6\%) than non-residents (44.0\%) returning from the Kingdom (P {\textless}0.001). Cough (91.6\%) and fever (90.5\%) were the most common presenting symptoms. A significantly higher proportion of non-residents (45.1\%) than residents (22.2\%) were being infected with influenza (P {\textless}0.001). After adjusting for age, travel destination, and admission month, non-residents were thrice as likely as residents to have an influenza infection (OR: 2.96; 95\% CI, 1.61-5.44; P {\textless}0.001). Discussion \& Conclusion(s): Influenza was common among returned travellers from MERS-affected areas, especially in nonresidents. Influenza vaccination and good personal hygiene should be actively promoted to all travellers to MERS-affected areas.},
language = {English},
number = {9 Supplement 1},
journal = {Annals of the Academy of Medicine Singapore},
author = {Chow, A. and Ho, H. and Win, M. K.},
year = {2016},
keywords = {*Saudi Arabia, *influenza vaccination, *travel, Singapore, Student t test, chi square test, controlled study, coughing, cross-sectional study, disease model, fever, hospital, human, logistic regression analysis, major clinical study, male, pentostatin, personal hygiene, resident, symptom},
pages = {S211},
}
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Method(s): We conducted an analytic cross-sectional study of suspected MERS patients admitted to our hospital from 25 September 2012 through 10 February 2016, to compare the clinical epidemiology in Singapore residents with non-residents. We compared differences in epidemiological and clinical characteristics, using t-test for continuous variables and chi-square test for categorical variables. We then constructed multivariable logistic regression models to assess for independent factors associated with influenza infection in the returned travellers. Result(s): MERS Co-V was not detected in the 262 patients investigated. Half were male and almost two-thirds (65.3%) were Singapore residents. Residents (mean 54.1 [SD 14.9] years) and non-residents (mean 56.8 [SD 16.1]) were similar in age (P = 0.171). Majority (60.7%) had returned from the Kingdom of Saudi Arabia, with significantly more Singapore residents (69.6%) than non-residents (44.0%) returning from the Kingdom (P \\textless0.001). Cough (91.6%) and fever (90.5%) were the most common presenting symptoms. A significantly higher proportion of non-residents (45.1%) than residents (22.2%) were being infected with influenza (P \\textless0.001). After adjusting for age, travel destination, and admission month, non-residents were thrice as likely as residents to have an influenza infection (OR: 2.96; 95% CI, 1.61-5.44; P \\textless0.001). Discussion & Conclusion(s): Influenza was common among returned travellers from MERS-affected areas, especially in nonresidents. 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