@article{ciereszko_glucose_2002,
	title = {Glucose and mannose regulate the expression of a major sucrose synthase gene in {Arabidopsis} via hexokinase-dependent mechanisms},
	volume = {40},
	issn = {0981-9428},
	url = {https://www.sciencedirect.com/science/article/pii/S0981942802014523},
	doi = {10/ct2hnm},
	abstract = {Sucrose synthase (SuSy) is an important enzyme involved in sucrose synthesis/breakdown in all plants. Sus1, a major SuSy gene in Arabidopsis thaliana, was upregulated by sucrose, glucose and D-mannose, but not 3-O-methylglucose, when those compounds were fed to excised leaves. Mannose was more effective than glucose or sucrose in the induction of Sus1, with strong effects observed at a concentration as low as 20 mM. When fed to the excised leaves, N-acetyl-glucosamine, an inhibitor of hexokinase (HXK) enzymatic activity, decreased sucrose- and glucose-dependent, but not mannose-dependent, upregulation of Sus1. The sucrose/glucose-dependent Sus1 expression was strongly induced in transgenic Arabidopsis HXK-overexpressing (OE) plants, whereas mannose-dependent Sus1 expression markedly decreased in OE, but not in HXK-“antisense”, Arabidopsis plants. Feeding with sucrose resulted in a marked increase of glucose content in leaves, suggesting that it is glucose rather than sucrose that serves as a signal in upregulating Sus1 expression in sucrose-fed plants. The data suggest that Sus1 is regulated by a HXK-dependent pathway, with glucose and mannose effects differentially sensed/transmitted via the HXK step.},
	language = {en},
	number = {11},
	urldate = {2021-10-19},
	journal = {Plant Physiology and Biochemistry},
	author = {Ciereszko, Iwona and Kleczkowski, Leszek A.},
	month = nov,
	year = {2002},
	keywords = {Arabidopsis thaliana, Gene expression, Sucrose synthesis, Sus1, UDP-glucose synthesis},
	pages = {907--911},
}

{"_id":"34jJc7PMpHvRkn6bH","bibbaseid":"ciereszko-kleczkowski-glucoseandmannoseregulatetheexpressionofamajorsucrosesynthasegeneinarabidopsisviahexokinasedependentmechanisms-2002","author_short":["Ciereszko, I.","Kleczkowski, L. A."],"bibdata":{"bibtype":"article","type":"article","title":"Glucose and mannose regulate the expression of a major sucrose synthase gene in Arabidopsis via hexokinase-dependent mechanisms","volume":"40","issn":"0981-9428","url":"https://www.sciencedirect.com/science/article/pii/S0981942802014523","doi":"10/ct2hnm","abstract":"Sucrose synthase (SuSy) is an important enzyme involved in sucrose synthesis/breakdown in all plants. Sus1, a major SuSy gene in Arabidopsis thaliana, was upregulated by sucrose, glucose and D-mannose, but not 3-O-methylglucose, when those compounds were fed to excised leaves. Mannose was more effective than glucose or sucrose in the induction of Sus1, with strong effects observed at a concentration as low as 20 mM. When fed to the excised leaves, N-acetyl-glucosamine, an inhibitor of hexokinase (HXK) enzymatic activity, decreased sucrose- and glucose-dependent, but not mannose-dependent, upregulation of Sus1. The sucrose/glucose-dependent Sus1 expression was strongly induced in transgenic Arabidopsis HXK-overexpressing (OE) plants, whereas mannose-dependent Sus1 expression markedly decreased in OE, but not in HXK-“antisense”, Arabidopsis plants. Feeding with sucrose resulted in a marked increase of glucose content in leaves, suggesting that it is glucose rather than sucrose that serves as a signal in upregulating Sus1 expression in sucrose-fed plants. The data suggest that Sus1 is regulated by a HXK-dependent pathway, with glucose and mannose effects differentially sensed/transmitted via the HXK step.","language":"en","number":"11","urldate":"2021-10-19","journal":"Plant Physiology and Biochemistry","author":[{"propositions":[],"lastnames":["Ciereszko"],"firstnames":["Iwona"],"suffixes":[]},{"propositions":[],"lastnames":["Kleczkowski"],"firstnames":["Leszek","A."],"suffixes":[]}],"month":"November","year":"2002","keywords":"Arabidopsis thaliana, Gene expression, Sucrose synthesis, Sus1, UDP-glucose synthesis","pages":"907–911","bibtex":"@article{ciereszko_glucose_2002,\n\ttitle = {Glucose and mannose regulate the expression of a major sucrose synthase gene in {Arabidopsis} via hexokinase-dependent mechanisms},\n\tvolume = {40},\n\tissn = {0981-9428},\n\turl = {https://www.sciencedirect.com/science/article/pii/S0981942802014523},\n\tdoi = {10/ct2hnm},\n\tabstract = {Sucrose synthase (SuSy) is an important enzyme involved in sucrose synthesis/breakdown in all plants. Sus1, a major SuSy gene in Arabidopsis thaliana, was upregulated by sucrose, glucose and D-mannose, but not 3-O-methylglucose, when those compounds were fed to excised leaves. Mannose was more effective than glucose or sucrose in the induction of Sus1, with strong effects observed at a concentration as low as 20 mM. When fed to the excised leaves, N-acetyl-glucosamine, an inhibitor of hexokinase (HXK) enzymatic activity, decreased sucrose- and glucose-dependent, but not mannose-dependent, upregulation of Sus1. The sucrose/glucose-dependent Sus1 expression was strongly induced in transgenic Arabidopsis HXK-overexpressing (OE) plants, whereas mannose-dependent Sus1 expression markedly decreased in OE, but not in HXK-“antisense”, Arabidopsis plants. Feeding with sucrose resulted in a marked increase of glucose content in leaves, suggesting that it is glucose rather than sucrose that serves as a signal in upregulating Sus1 expression in sucrose-fed plants. The data suggest that Sus1 is regulated by a HXK-dependent pathway, with glucose and mannose effects differentially sensed/transmitted via the HXK step.},\n\tlanguage = {en},\n\tnumber = {11},\n\turldate = {2021-10-19},\n\tjournal = {Plant Physiology and Biochemistry},\n\tauthor = {Ciereszko, Iwona and Kleczkowski, Leszek A.},\n\tmonth = nov,\n\tyear = {2002},\n\tkeywords = {Arabidopsis thaliana, Gene expression, Sucrose synthesis, Sus1, UDP-glucose synthesis},\n\tpages = {907--911},\n}\n\n\n\n","author_short":["Ciereszko, I.","Kleczkowski, L. A."],"key":"ciereszko_glucose_2002","id":"ciereszko_glucose_2002","bibbaseid":"ciereszko-kleczkowski-glucoseandmannoseregulatetheexpressionofamajorsucrosesynthasegeneinarabidopsisviahexokinasedependentmechanisms-2002","role":"author","urls":{"Paper":"https://www.sciencedirect.com/science/article/pii/S0981942802014523"},"keyword":["Arabidopsis thaliana","Gene expression","Sucrose synthesis","Sus1","UDP-glucose synthesis"],"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://bibbase.org/zotero/upscpub","dataSources":["Tu3jPdZyJF3j547xT","9cGcv2t8pRzC92kzs","3zTPPmKj8BiTcpc6C"],"keywords":["arabidopsis thaliana","gene expression","sucrose synthesis","sus1","udp-glucose synthesis"],"search_terms":["glucose","mannose","regulate","expression","major","sucrose","synthase","gene","arabidopsis","via","hexokinase","dependent","mechanisms","ciereszko","kleczkowski"],"title":"Glucose and mannose regulate the expression of a major sucrose synthase gene in Arabidopsis via hexokinase-dependent mechanisms","year":2002}