Quantifying the Added Value of New Biomarkers: How and How Not. Cook, N. R. Diagnostic and Prognostic Research, 2(1):14, July, 2018.
doi  abstract   bibtex   
Over the past few decades, interest in biomarkers to enhance predictive modeling has soared. Methodology for evaluating these has also been an active area of research. There are now several performance measures available for quantifying the added value of biomarkers. This commentary provides an overview of methods currently used to evaluate new biomarkers, describes their strengths and limitations, and offers some suggestions on their use.
@article{coo18qua,
  title = {Quantifying the Added Value of New Biomarkers: How and How Not},
  volume = {2},
  issn = {2397-7523},
  shorttitle = {Quantifying the Added Value of New Biomarkers},
  abstract = {Over the past few decades, interest in biomarkers to enhance predictive modeling has soared. Methodology for evaluating these has also been an active area of research. There are now several performance measures available for quantifying the added value of biomarkers. This commentary provides an overview of methods currently used to evaluate new biomarkers, describes their strengths and limitations, and offers some suggestions on their use.},
  number = {1},
  journal = {Diagnostic and Prognostic Research},
  doi = {10.1186/s41512-018-0037-2},
  author = {Cook, Nancy R.},
  month = jul,
  year = {2018},
  keywords = {validation,biomarker,roc,accuracy},
  pages = {14}
}

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