The Political Life of Mutagens: A History of the Ames Test. Creager, A. N. In Boudia, S. & Jas, N., editors, Powerless Science?, of Science and Politics in a Toxic World, pages 46–64. Berghahn Books, 1 edition, 2014. ![The Political Life of Mutagens: A History of the Ames Test [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper abstract bibtex In 1973, Bruce N. Ames, a professor of biochemistry at the University of California, Berkeley, introduced a new assay for use in evaluating carcinogenicity. The test relied on four mutant strains of\textlessem\textgreaterSalmonella\textless/em\textgreaterthat Ames’s group had developed, drawing on years of experience using such bacteria in studies of metabolism and mutagenesis. These strains were deficient in their ability to synthesize a particular amino acid, histidine, so they required this supplement in the growth media. Each of the four strains could be used to genetically screen compounds inducing a specific kind of mutation in the DNA sequence. These registered as
@incollection{creager_political_2014,
edition = {1},
series = {Science and {Politics} in a {Toxic} {World}},
title = {The {Political} {Life} of {Mutagens}: {A} {History} of the {Ames} {Test}},
isbn = {978-1-78238-236-2},
url = {http://www.jstor.org/stable/j.ctt9qd0tj.7},
abstract = {In 1973, Bruce N. Ames, a professor of biochemistry at the University of California, Berkeley, introduced a new assay for use in evaluating carcinogenicity. The test relied on four mutant strains of{\textless}em{\textgreater}Salmonella{\textless}/em{\textgreater}that Ames’s group had developed, drawing on years of experience using such bacteria in studies of metabolism and mutagenesis. These strains were deficient in their ability to synthesize a particular amino acid, histidine, so they required this supplement in the growth media. Each of the four strains could be used to genetically screen compounds inducing a specific kind of mutation in the DNA sequence. These registered as},
urldate = {2023-03-30},
booktitle = {Powerless {Science}?},
publisher = {Berghahn Books},
author = {Creager, Angela N.H.},
editor = {Boudia, Soraya and Jas, Nathalie},
year = {2014},
keywords = {6 Ignorance and public policies, PRINTED (Fonds papier)},
pages = {46--64},
}
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