COVID-19 in elderly kidney transplant recipients. Crespo, M., Pérez‐Sáez, M. J., Redondo‐Pachón, D., Llinàs‐Mallol, L., Montero, M. M., Villar‐García, J., Arias‐Cabrales, C., Buxeda, A., Burballa, C., Vázquez, S., López, T., Moreno, F., Mir, M., Outón, S., Sierra, A., Collado, S., Barrios, C., Rodríguez, E., Sans, L., Barbosa, F., Cao, H., Arenas, M. D., Güerri‐Fernández, R., Horcajada, J. P., & Pascual, J. American Journal of Transplantation. _eprint: https://onlinelibrary.wiley.com/doi/pdf/10.1111/ajt.16096![COVID-19 in elderly kidney transplant recipients [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex The SARS-Cov-2 infection disease (COVID-19) pandemic has posed at risk the kidney transplant (KT) population, particularly the elderly recipients. From March 12 until April 4, 2020, we diagnosed COVID-19 in 16 of our 324 KT patients aged ≥65 years old (4.9%). Many of them had had contact with healthcare facilities in the month prior to infection. Median time of symptom onset to admission was 7 days. All presented with fever and all but one with pneumonia. Up to 33% showed renal graft dysfunction. At infection diagnosis, mTOR inhibitors or mycophenolate were withdrawn. Tacrolimus was withdrawn in 70%. The main treatment combination was hydroxychloroquine and azithromycin. A subset of patients was treated with anti-retroviral and tocilizumab. Short-term fatality rate was 50% at a median time since admission of 3 days. Those who died were more frequently obese, frail, and had underlying heart disease. Although a higher respiratory rate was observed at admission in nonsurvivors, symptoms at presentation were similar between both groups. Patients who died were more anemic, lymphopenic, and showed higher D-dimer, C-reactive protein, and IL-6 at their first tests. COVID-19 is frequent among the elderly KT population and associates a very early and high mortality rate.
@article{crespo_covid-19_nodate,
title = {{COVID}-19 in elderly kidney transplant recipients},
volume = {n/a},
copyright = {© 2020 The American Society of Transplantation and the American Society of Transplant Surgeons},
issn = {1600-6143},
url = {https://onlinelibrary.wiley.com/doi/abs/10.1111/ajt.16096},
doi = {10.1111/ajt.16096},
abstract = {The SARS-Cov-2 infection disease (COVID-19) pandemic has posed at risk the kidney transplant (KT) population, particularly the elderly recipients. From March 12 until April 4, 2020, we diagnosed COVID-19 in 16 of our 324 KT patients aged ≥65 years old (4.9\%). Many of them had had contact with healthcare facilities in the month prior to infection. Median time of symptom onset to admission was 7 days. All presented with fever and all but one with pneumonia. Up to 33\% showed renal graft dysfunction. At infection diagnosis, mTOR inhibitors or mycophenolate were withdrawn. Tacrolimus was withdrawn in 70\%. The main treatment combination was hydroxychloroquine and azithromycin. A subset of patients was treated with anti-retroviral and tocilizumab. Short-term fatality rate was 50\% at a median time since admission of 3 days. Those who died were more frequently obese, frail, and had underlying heart disease. Although a higher respiratory rate was observed at admission in nonsurvivors, symptoms at presentation were similar between both groups. Patients who died were more anemic, lymphopenic, and showed higher D-dimer, C-reactive protein, and IL-6 at their first tests. COVID-19 is frequent among the elderly KT population and associates a very early and high mortality rate.},
language = {en},
number = {n/a},
urldate = {2020-08-25},
journal = {American Journal of Transplantation},
author = {Crespo, Marta and Pérez‐Sáez, María J. and Redondo‐Pachón, Dolores and Llinàs‐Mallol, Laura and Montero, María M. and Villar‐García, Judith and Arias‐Cabrales, Carlos and Buxeda, Anna and Burballa, Carla and Vázquez, Susana and López, Thais and Moreno, Fátima and Mir, Marisa and Outón, Sara and Sierra, Adriana and Collado, Silvia and Barrios, Clara and Rodríguez, Eva and Sans, Laia and Barbosa, Francesc and Cao, Higini and Arenas, María D. and Güerri‐Fernández, Roberto and Horcajada, Juan P. and Pascual, Julio},
note = {\_eprint: https://onlinelibrary.wiley.com/doi/pdf/10.1111/ajt.16096},
keywords = {Article, Nefrologia, clinical research/practice, infection and infectious agents – viral, kidney transplantation/nephrology, patient survival},
}
Downloads: 0
{"_id":"GL6vmsdYkwEQStSpA","bibbaseid":"crespo-prezsez-redondopachn-llinsmallol-montero-villargarca-ariascabrales-buxeda-etal-covid19inelderlykidneytransplantrecipients","authorIDs":[],"author_short":["Crespo, M.","Pérez‐Sáez, M. J.","Redondo‐Pachón, D.","Llinàs‐Mallol, L.","Montero, M. M.","Villar‐García, J.","Arias‐Cabrales, C.","Buxeda, A.","Burballa, C.","Vázquez, S.","López, T.","Moreno, F.","Mir, M.","Outón, S.","Sierra, A.","Collado, S.","Barrios, C.","Rodríguez, E.","Sans, L.","Barbosa, F.","Cao, H.","Arenas, M. D.","Güerri‐Fernández, R.","Horcajada, J. P.","Pascual, J."],"bibdata":{"bibtype":"article","type":"article","title":"COVID-19 in elderly kidney transplant recipients","volume":"n/a","copyright":"© 2020 The American Society of Transplantation and the American Society of Transplant Surgeons","issn":"1600-6143","url":"https://onlinelibrary.wiley.com/doi/abs/10.1111/ajt.16096","doi":"10.1111/ajt.16096","abstract":"The SARS-Cov-2 infection disease (COVID-19) pandemic has posed at risk the kidney transplant (KT) population, particularly the elderly recipients. From March 12 until April 4, 2020, we diagnosed COVID-19 in 16 of our 324 KT patients aged ≥65 years old (4.9%). Many of them had had contact with healthcare facilities in the month prior to infection. Median time of symptom onset to admission was 7 days. All presented with fever and all but one with pneumonia. Up to 33% showed renal graft dysfunction. At infection diagnosis, mTOR inhibitors or mycophenolate were withdrawn. Tacrolimus was withdrawn in 70%. The main treatment combination was hydroxychloroquine and azithromycin. A subset of patients was treated with anti-retroviral and tocilizumab. Short-term fatality rate was 50% at a median time since admission of 3 days. Those who died were more frequently obese, frail, and had underlying heart disease. Although a higher respiratory rate was observed at admission in nonsurvivors, symptoms at presentation were similar between both groups. Patients who died were more anemic, lymphopenic, and showed higher D-dimer, C-reactive protein, and IL-6 at their first tests. COVID-19 is frequent among the elderly KT population and associates a very early and high mortality rate.","language":"en","number":"n/a","urldate":"2020-08-25","journal":"American Journal of Transplantation","author":[{"propositions":[],"lastnames":["Crespo"],"firstnames":["Marta"],"suffixes":[]},{"propositions":[],"lastnames":["Pérez‐Sáez"],"firstnames":["María","J."],"suffixes":[]},{"propositions":[],"lastnames":["Redondo‐Pachón"],"firstnames":["Dolores"],"suffixes":[]},{"propositions":[],"lastnames":["Llinàs‐Mallol"],"firstnames":["Laura"],"suffixes":[]},{"propositions":[],"lastnames":["Montero"],"firstnames":["María","M."],"suffixes":[]},{"propositions":[],"lastnames":["Villar‐García"],"firstnames":["Judith"],"suffixes":[]},{"propositions":[],"lastnames":["Arias‐Cabrales"],"firstnames":["Carlos"],"suffixes":[]},{"propositions":[],"lastnames":["Buxeda"],"firstnames":["Anna"],"suffixes":[]},{"propositions":[],"lastnames":["Burballa"],"firstnames":["Carla"],"suffixes":[]},{"propositions":[],"lastnames":["Vázquez"],"firstnames":["Susana"],"suffixes":[]},{"propositions":[],"lastnames":["López"],"firstnames":["Thais"],"suffixes":[]},{"propositions":[],"lastnames":["Moreno"],"firstnames":["Fátima"],"suffixes":[]},{"propositions":[],"lastnames":["Mir"],"firstnames":["Marisa"],"suffixes":[]},{"propositions":[],"lastnames":["Outón"],"firstnames":["Sara"],"suffixes":[]},{"propositions":[],"lastnames":["Sierra"],"firstnames":["Adriana"],"suffixes":[]},{"propositions":[],"lastnames":["Collado"],"firstnames":["Silvia"],"suffixes":[]},{"propositions":[],"lastnames":["Barrios"],"firstnames":["Clara"],"suffixes":[]},{"propositions":[],"lastnames":["Rodríguez"],"firstnames":["Eva"],"suffixes":[]},{"propositions":[],"lastnames":["Sans"],"firstnames":["Laia"],"suffixes":[]},{"propositions":[],"lastnames":["Barbosa"],"firstnames":["Francesc"],"suffixes":[]},{"propositions":[],"lastnames":["Cao"],"firstnames":["Higini"],"suffixes":[]},{"propositions":[],"lastnames":["Arenas"],"firstnames":["María","D."],"suffixes":[]},{"propositions":[],"lastnames":["Güerri‐Fernández"],"firstnames":["Roberto"],"suffixes":[]},{"propositions":[],"lastnames":["Horcajada"],"firstnames":["Juan","P."],"suffixes":[]},{"propositions":[],"lastnames":["Pascual"],"firstnames":["Julio"],"suffixes":[]}],"note":"_eprint: https://onlinelibrary.wiley.com/doi/pdf/10.1111/ajt.16096","keywords":"Article, Nefrologia, clinical research/practice, infection and infectious agents – viral, kidney transplantation/nephrology, patient survival","bibtex":"@article{crespo_covid-19_nodate,\n\ttitle = {{COVID}-19 in elderly kidney transplant recipients},\n\tvolume = {n/a},\n\tcopyright = {© 2020 The American Society of Transplantation and the American Society of Transplant Surgeons},\n\tissn = {1600-6143},\n\turl = {https://onlinelibrary.wiley.com/doi/abs/10.1111/ajt.16096},\n\tdoi = {10.1111/ajt.16096},\n\tabstract = {The SARS-Cov-2 infection disease (COVID-19) pandemic has posed at risk the kidney transplant (KT) population, particularly the elderly recipients. From March 12 until April 4, 2020, we diagnosed COVID-19 in 16 of our 324 KT patients aged ≥65 years old (4.9\\%). Many of them had had contact with healthcare facilities in the month prior to infection. Median time of symptom onset to admission was 7 days. All presented with fever and all but one with pneumonia. Up to 33\\% showed renal graft dysfunction. At infection diagnosis, mTOR inhibitors or mycophenolate were withdrawn. Tacrolimus was withdrawn in 70\\%. The main treatment combination was hydroxychloroquine and azithromycin. A subset of patients was treated with anti-retroviral and tocilizumab. Short-term fatality rate was 50\\% at a median time since admission of 3 days. Those who died were more frequently obese, frail, and had underlying heart disease. Although a higher respiratory rate was observed at admission in nonsurvivors, symptoms at presentation were similar between both groups. Patients who died were more anemic, lymphopenic, and showed higher D-dimer, C-reactive protein, and IL-6 at their first tests. COVID-19 is frequent among the elderly KT population and associates a very early and high mortality rate.},\n\tlanguage = {en},\n\tnumber = {n/a},\n\turldate = {2020-08-25},\n\tjournal = {American Journal of Transplantation},\n\tauthor = {Crespo, Marta and Pérez‐Sáez, María J. and Redondo‐Pachón, Dolores and Llinàs‐Mallol, Laura and Montero, María M. and Villar‐García, Judith and Arias‐Cabrales, Carlos and Buxeda, Anna and Burballa, Carla and Vázquez, Susana and López, Thais and Moreno, Fátima and Mir, Marisa and Outón, Sara and Sierra, Adriana and Collado, Silvia and Barrios, Clara and Rodríguez, Eva and Sans, Laia and Barbosa, Francesc and Cao, Higini and Arenas, María D. and Güerri‐Fernández, Roberto and Horcajada, Juan P. and Pascual, Julio},\n\tnote = {\\_eprint: https://onlinelibrary.wiley.com/doi/pdf/10.1111/ajt.16096},\n\tkeywords = {Article, Nefrologia, clinical research/practice, infection and infectious agents – viral, kidney transplantation/nephrology, patient survival},\n}\n\n","author_short":["Crespo, M.","Pérez‐Sáez, M. J.","Redondo‐Pachón, D.","Llinàs‐Mallol, L.","Montero, M. M.","Villar‐García, J.","Arias‐Cabrales, C.","Buxeda, A.","Burballa, C.","Vázquez, S.","López, T.","Moreno, F.","Mir, M.","Outón, S.","Sierra, A.","Collado, S.","Barrios, C.","Rodríguez, E.","Sans, L.","Barbosa, F.","Cao, H.","Arenas, M. D.","Güerri‐Fernández, R.","Horcajada, J. P.","Pascual, J."],"key":"crespo_covid-19_nodate","id":"crespo_covid-19_nodate","bibbaseid":"crespo-prezsez-redondopachn-llinsmallol-montero-villargarca-ariascabrales-buxeda-etal-covid19inelderlykidneytransplantrecipients","role":"author","urls":{"Paper":"https://onlinelibrary.wiley.com/doi/abs/10.1111/ajt.16096"},"keyword":["Article","Nefrologia","clinical research/practice","infection and infectious agents – viral","kidney transplantation/nephrology","patient survival"],"downloads":0,"html":"","metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://bibbase.org/zotero/Bibliotecacst","creationDate":"2021-01-20T09:38:08.718Z","downloads":0,"keywords":["article","nefrologia","clinical research/practice","infection and infectious agents – viral","kidney transplantation/nephrology","patient survival"],"search_terms":["covid","elderly","kidney","transplant","recipients","crespo","pérez‐sáez","redondo‐pachón","llinàs‐mallol","montero","villar‐garcía","arias‐cabrales","buxeda","burballa","vázquez","lópez","moreno","mir","outón","sierra","collado","barrios","rodríguez","sans","barbosa","cao","arenas","güerri‐fernández","horcajada","pascual"],"title":"COVID-19 in elderly kidney transplant recipients","year":null,"dataSources":["TR9pX4mH5rDPr29Zo"]}