FUSION PROTEIN CONSTRUCTSCOMPRISING ANTI-C3d ANTIBODY AND FACTOR H. Curtis, M. S., Storek, M., Violette, S. M., Kalled, S. L., Fahnoe, K. C., Huang, C. R., Stark, E. G., Taylor, F. R., Caravella, J. A., & Holers, V. M. January 2021.
FUSION PROTEIN CONSTRUCTSCOMPRISING ANTI-C3d ANTIBODY AND FACTOR H [link]Paper  abstract   bibtex   1 download  
Provided herein are fusion protein constructs that can bind a complement-associated antigen, comprising a targeting moiety and a complement modulator protein, or a fragment thereof or a variant thereof. The targeting moiety is an antibody or an antigen binding fragment thereof, in some examples. Further provided are methods of using the fusion protein constructs, for example, in treating complement mediation conditions.
@patent{curtis_fusion_2021,
	title = {{FUSION} {PROTEIN} {CONSTRUCTSCOMPRISING} {ANTI}-{C3d} {ANTIBODY} {AND} {FACTOR} {H}},
	url = {https://www.freepatentsonline.com/y2021/0009669.html},
	abstract = {Provided herein are fusion protein constructs that can bind a complement-associated antigen, comprising a targeting moiety and a complement modulator protein, or a fragment thereof or a variant thereof. The targeting moiety is an antibody or an antigen binding fragment thereof, in some examples. Further provided are methods of using the fusion protein constructs, for example, in treating complement mediation conditions.},
	nationality = {United States},
	assignee = {Q32 Bio Inc. (Cambridge, MA, US)},
	number = {20210009669},
	urldate = {2021-01-26},
	author = {Curtis, Michael Steven and Storek, Michael and Violette, Shelia Marie and Kalled, Susan L. and Fahnoe, Kelly C. and Huang, Cheng Ran and Stark, Ellen Garber and Taylor, Frederick Robbins and Caravella, Justin Andrew and Holers, Vernon Michael},
	collaborator = {Gambel, Phillip and MCCARTER \& ENGLISH, LLP BOSTON},
	month = jan,
	year = {2021},
	keywords = {Application - Antibody Validation / Epitope Mapping, Country - USA, Mouse, PEPperCHIP - Customized - Linear, PEPperMAP - Epitope Mapping - Linear, Sample Type - Monoclonal/polyclonal antibody},
}

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