@article{RN250,
   author = {Davalos, R. V. and Rubinsky, B. and Otten, D. M.},
   title = {A feasibility study for electrical impedance tomography as a means to monitor tissue electroporation for molecular medicine},
   journal = {IEEE Trans Biomed Eng},
   volume = {49},
   number = {4},
   pages = {400-3},
   note = {Davalos, Rafael V
Rubinsky, Boris
Otten, David M
1 R21 RR15252-01/RR/NCRR NIH HHS/United States
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
United States
2002/04/11
IEEE Trans Biomed Eng. 2002 Apr;49(4):400-3. doi: 10.1109/10.991168.},
   abstract = {Molecular medicine involves the introduction of macromolecules, such as drugs or gene constructs, into specific cells of the body. Electroporation, which uses electric pulses to permeate cell membranes, is a method for achieving this. However, as with other molecular medicine procedures, it lacks a real-time mechanism to detect and control which cells have been affected. We propose and demonstrate, via computer simulation, that electrical impedance tomography has the potential for detecting and imaging electroporation of cells in tissue in real-time, thereby providing feedback for controlling electroporation.},
   keywords = {Computer Simulation
Electric Impedance
Electroporation/*methods
Feasibility Studies
Macromolecular Substances
Molecular Biology
Tomography/*methods},
   ISSN = {0018-9294 (Print)
0018-9294},
   DOI = {10.1109/10.991168},
   year = {2002},
   type = {Journal Article}
}

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