Sialic acids in infection and their potential use in detection and protection against pathogens. Dedola, S., Ahmadipour, S., de Andrade, P., Baker, A. N., Boshra, A. N., Chessa, S., Gibson, M. I., Hernando, P. J., Ivanova, I. M., Lloyd, J. E., Marin, M. J., Munro-Clark, A. J., Pergolizzi, G., Richards, S., Ttofi, I., Wagstaff, B. A., & Field, R. A. RSC CHEMICAL BIOLOGY, 5(3):167–188, March, 2024. Norwich Res Pk
doi  abstract   bibtex   
In structural terms, the sialic acids are a large family of nine carbon sugars based around an alpha-keto acid core. They are widely spread in nature, where they are often found to be involved in molecular recognition processes, including in development, immunology, health and disease. The prominence of sialic acids in infection is a result of their exposure at the non-reducing terminus of glycans in diverse glycolipids and glycoproteins. Herein, we survey representative aspects of sialic acid structure, recognition and exploitation in relation to infectious diseases, their diagnosis and prevention or treatment. Examples covered span influenza virus and Covid-19, Leishmania and Trypanosoma, algal viruses, Campylobacter, Streptococci and Helicobacter, and commensal Ruminococci.An overview of sialic acid involvement in infection and exploitation in diagnostics and therapeutics.
@article{dedola_sialic_2024,
	title = {Sialic acids in infection and their potential use in detection and protection against pathogens},
	volume = {5},
	issn = {2633-0679},
	doi = {10.1039/d3cb00155e},
	abstract = {In structural terms, the sialic acids are a large family of nine carbon sugars based around an alpha-keto acid core. They are widely spread in nature, where they are often found to be involved in molecular recognition processes, including in development, immunology, health and disease. The prominence of sialic acids in infection is a result of their exposure at the non-reducing terminus of glycans in diverse glycolipids and glycoproteins. Herein, we survey representative aspects of sialic acid structure, recognition and exploitation in relation to infectious diseases, their diagnosis and prevention or treatment. Examples covered span influenza virus and Covid-19, Leishmania and Trypanosoma, algal viruses, Campylobacter, Streptococci and Helicobacter, and commensal Ruminococci.An overview of sialic acid involvement in infection and exploitation in diagnostics and therapeutics.},
	number = {3},
	urldate = {2024-01-23},
	journal = {RSC CHEMICAL BIOLOGY},
	author = {Dedola, Simone and Ahmadipour, Sanaz and de Andrade, Peterson and Baker, Alexander N. and Boshra, Andrew N. and Chessa, Simona and Gibson, Matthew I. and Hernando, Pedro J. and Ivanova, Irina M. and Lloyd, Jessica E. and Marin, Maria J. and Munro-Clark, Alexandra J. and Pergolizzi, Giulia and Richards, Sarah-Jane and Ttofi, Iakovia and Wagstaff, Ben A. and Field, Robert A.},
	month = mar,
	year = {2024},
	note = {Norwich Res Pk},
	pages = {167--188},
}

Downloads: 0