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@article{ deglopper_efficient_2014,
  title = {Efficient access to 3-substituted-γ-hydroxylactams: the uncatalyzed addition of diorganozinc reagents to cyclic imides with heterocyclic substitution},
  volume = {55},
  issn = {0040-4039},
  shorttitle = {Efficient access to 3-substituted-γ-hydroxylactams},
  url = {http://www.sciencedirect.com/science/article/pii/S0040403914001865},
  doi = {10.1016/j.tetlet.2014.01.130},
  abstract = {A range of 3-substituted-γ-hydroxylactams have been prepared via the uncatalyzed addition of organozinc nucleophiles to cyclic imides. This reactivity is primarily limited to imides containing heterocyclic N-substitution, but proceeds efficiently with a variety of diorganozinc reagents, including those prepared and utilized without purification, as well as organozinc halides. It is hypothesized that the presence of a Lewis basic directing group is required for optimum reactivity.},
  number = {10},
  urldate = {2014-08-05TZ},
  journal = {Tetrahedron Letters},
  author = {DeGlopper, Kimberly S. and Dennis, Joseph M. and Johnson, Jeffrey B.},
  month = {March},
  year = {2014},
  keywords = {Directing groups, Imides, Nucleophilic addition, Organozinc reagents},
  pages = {1843--1845}
}